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The map label for this gene is petH [H]

Identifier: 37521864

GI number: 37521864

Start: 2458009

End: 2458899

Strand: Reverse

Name: petH [H]

Synonym: gvip312

Alternate gene names: 37521864

Gene position: 2458899-2458009 (Counterclockwise)

Preceding gene: 37521868

Following gene: 37521863

Centisome position: 52.78

GC content: 60.72

Gene sequence:

>891_bases
ATGGCCCACGCCGCCACACGTACCTTCGAGGTCCCCGTCAACATTTACCGCCCGGCCAGTCCGTTCCGGGGCAAGGCGCT
TCAAAACATTAACCTGACACCCGACGACCCGGACAACGATGTGCGCCACGTTGTCCTCGACTTGAGCGGGGGCGATCTGC
GCTACTTCGAAGGCCAGAGCATCGGCATCGTTCCCCCGGGCACCGACGCCCAGGGCAAGCCCCACAAGTTGCGGCTCTAC
TCGATCGCCTCCAGCCGCATCGGCGACAACAAAGACGGCAAGACCGTTTCGCTGTGCGTCAAGCGCGTCGTCTACAAGCA
CCCCGAGACCGGTGAAATTGTGCGCGGCGTCGCGTCGAACTTTATTTGCGATCTGGCTCCCGGCGACGATGTGTCGATCA
CCGGCCCCACCGGTAAGACCTTTTTGCTGCCCGAAGATCCGAGCACCAATCTGGTTTTGATCGCCACCGGCACCGGCATT
GCGCCCTTCCGGGCCTTCCTGCGCCGCATCTACGACGAAATGGACACTCCCTGGCAGGGCAAGGTGTGGTTGTTCTTCGG
GATGCAAAATTCCAACAGCTACCTTTACCAGGATGAACTGGCCGGTTACACCGCCAAGGGCGACTTCGAGATCGTCGAAG
CGATCAGCCGCGAGCAAAAGAACGCCCAGGGCGGTCGCATGTACGTCCAGCACCGCATCGCCGAGCACGCTGCGGCGCTG
TGGGAACTGATTTCAGGCGGCAACACCTACACGTACATCTGCGGCCTCAAGGGCATGGAAGACGGCATCGACGACGCATT
TACCGCCGCCGCCGCCGCCAAGGACACCGTCTGGAAAGATTACCGCTACAATCTCAAGCAATCCGGTTTTTGGCACGTCG
AAACCTACTAA

Upstream 100 bases:

>100_bases
CGATGCAATGTGCCGAGCTTTGCCGGTGAGGTTTTACACTGGGCATAATCTGTCGATCGTTACCCGCTGCTGTTTCGCCG
TCTTCAGGAGATAGCCGATC

Downstream 100 bases:

>100_bases
TGTGACCATTCCTTTCCAGTCCTCCACCGCTCCGACCCTTGGGGTCGAGATGGAACTACAAATCATCGACCCCGCGACGG
GCAACCTCACCCCGCGCGGG

Product: ferredoxin--NADP+ reductase

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAHAATRTFEVPVNIYRPASPFRGKALQNINLTPDDPDNDVRHVVLDLSGGDLRYFEGQSIGIVPPGTDAQGKPHKLRLY
SIASSRIGDNKDGKTVSLCVKRVVYKHPETGEIVRGVASNFICDLAPGDDVSITGPTGKTFLLPEDPSTNLVLIATGTGI
APFRAFLRRIYDEMDTPWQGKVWLFFGMQNSNSYLYQDELAGYTAKGDFEIVEAISREQKNAQGGRMYVQHRIAEHAAAL
WELISGGNTYTYICGLKGMEDGIDDAFTAAAAAKDTVWKDYRYNLKQSGFWHVETY

Sequences:

>Translated_296_residues
MAHAATRTFEVPVNIYRPASPFRGKALQNINLTPDDPDNDVRHVVLDLSGGDLRYFEGQSIGIVPPGTDAQGKPHKLRLY
SIASSRIGDNKDGKTVSLCVKRVVYKHPETGEIVRGVASNFICDLAPGDDVSITGPTGKTFLLPEDPSTNLVLIATGTGI
APFRAFLRRIYDEMDTPWQGKVWLFFGMQNSNSYLYQDELAGYTAKGDFEIVEAISREQKNAQGGRMYVQHRIAEHAAAL
WELISGGNTYTYICGLKGMEDGIDDAFTAAAAAKDTVWKDYRYNLKQSGFWHVETY
>Mature_295_residues
AHAATRTFEVPVNIYRPASPFRGKALQNINLTPDDPDNDVRHVVLDLSGGDLRYFEGQSIGIVPPGTDAQGKPHKLRLYS
IASSRIGDNKDGKTVSLCVKRVVYKHPETGEIVRGVASNFICDLAPGDDVSITGPTGKTFLLPEDPSTNLVLIATGTGIA
PFRAFLRRIYDEMDTPWQGKVWLFFGMQNSNSYLYQDELAGYTAKGDFEIVEAISREQKNAQGGRMYVQHRIAEHAAALW
ELISGGNTYTYICGLKGMEDGIDDAFTAAAAAKDTVWKDYRYNLKQSGFWHVETY

Specific function: Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Compo

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI24041029, Length=231, Percent_Identity=29.004329004329, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI127139033, Length=200, Percent_Identity=31.5, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221316705, Length=238, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254422, Length=184, Percent_Identity=31.5217391304348, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI7657393, Length=233, Percent_Identity=26.1802575107296, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI221316709, Length=232, Percent_Identity=26.7241379310345, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI169790958, Length=152, Percent_Identity=30.9210526315789, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI169790956, Length=152, Percent_Identity=30.9210526315789, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789123, Length=188, Percent_Identity=36.7021276595745, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554134, Length=209, Percent_Identity=31.1004784688995, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321832, Length=150, Percent_Identity=34, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24582192, Length=185, Percent_Identity=33.5135135135135, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137192, Length=185, Percent_Identity=33.5135135135135, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583543, Length=213, Percent_Identity=32.3943661971831, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI78706876, Length=213, Percent_Identity=32.3943661971831, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI78706872, Length=213, Percent_Identity=32.3943661971831, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24660907, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24660903, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012146
- InterPro:   IPR015701
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 32763; Mature: 32632

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAATRTFEVPVNIYRPASPFRGKALQNINLTPDDPDNDVRHVVLDLSGGDLRYFEGQS
CCCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCE
IGIVPPGTDAQGKPHKLRLYSIASSRIGDNKDGKTVSLCVKRVVYKHPETGEIVRGVASN
EEEECCCCCCCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
FICDLAPGDDVSITGPTGKTFLLPEDPSTNLVLIATGTGIAPFRAFLRRIYDEMDTPWQG
CEEECCCCCCEEEECCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
KVWLFFGMQNSNSYLYQDELAGYTAKGDFEIVEAISREQKNAQGGRMYVQHRIAEHAAAL
EEEEEEEEECCCCEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
WELISGGNTYTYICGLKGMEDGIDDAFTAAAAAKDTVWKDYRYNLKQSGFWHVETY
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
AHAATRTFEVPVNIYRPASPFRGKALQNINLTPDDPDNDVRHVVLDLSGGDLRYFEGQS
CCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCE
IGIVPPGTDAQGKPHKLRLYSIASSRIGDNKDGKTVSLCVKRVVYKHPETGEIVRGVASN
EEEECCCCCCCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
FICDLAPGDDVSITGPTGKTFLLPEDPSTNLVLIATGTGIAPFRAFLRRIYDEMDTPWQG
CEEECCCCCCEEEECCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
KVWLFFGMQNSNSYLYQDELAGYTAKGDFEIVEAISREQKNAQGGRMYVQHRIAEHAAAL
EEEEEEEEECCCCEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
WELISGGNTYTYICGLKGMEDGIDDAFTAAAAAKDTVWKDYRYNLKQSGFWHVETY
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6430889; 6415047 [H]