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The map label for this gene is prk [H]

Identifier: 37521691

GI number: 37521691

Start: 2276460

End: 2277497

Strand: Reverse

Name: prk [H]

Synonym: gvip292

Alternate gene names: 37521691

Gene position: 2277497-2276460 (Counterclockwise)

Preceding gene: 37521692

Following gene: 37521690

Centisome position: 48.88

GC content: 58.09

Gene sequence:

>1038_bases
ATGGAAACCCTTACCGCAACAGAGACGCAGCCTATGACCAACTCTGTGCAATTTGTCTGCGCCACGGCGCGTCAACAACT
CAAACAGTTGCGATCTCCGATTATTGTTGGTGTTGCAGGCGACAGCGGCAGCGGCAAAACCACCTACAGCAACGGCATTC
GTCGCCTGCTGGGAAGCGATCTGGTTTCGACGCTCTGCACGGACGGCTACCACAAAGAGGACCGCGAACAGCGCCAGATC
AGCGGCCGTCTGCCCCTGGACCCGGCGGCCAACCACCTGGACCGGTTGGCCGAGCACCTCAAAGCCCTCAAACAGGGAAA
GGCCGTGCCCATCCCCGTCTATAACCACGGCTCGGGCAAGTTTGAGCAGCCCGAGAATTTTGTGCCGACGCCGATTGTCG
TCGTGGAAGGCTTGCATACGCTGTACCCGGAATTGATCCCGTACCTCGATTTCAGCCTCTACGTCGATCCGGATCATCCC
GTCAAGTGGCAGTGGAAATGGGAGCGCGACCTCAAGCGCCGCGGTCACAAAGCCGAACAGCTCGAGCAGGAGATGCTGCA
GCGCGAAGCCGCCTTCAAGCGTTGGATCGATTTTCAAAAGATTGACGCCAACGTGGTGATCAAAATTTTTCATAGCCAAC
TGCAGTGCCTTGCCCCCCACCAGTTCACCGGCATCCTGCCCAACCCGTGCTACAAAGTGGAACTGATCCTGCAGCCGGCT
CCTGTGCCGCTGCCGACGTTGCCCCTGCCATTTGATCTCGCGGCGATGCTCGCCGTCGACCAGCCCCCTTTTATGCTGGC
GGCGGTCCCCTACCGCTACTGGGGGCGCTCGGCGATTGCCATTCACCTCGACGGTGTGCTGTCGCAAAAGACCATCGCCG
GGCTCGAAGACTATATCGTTAACTACACAGGCATTCCCACGGATGAGGCCATTCCGGAGGAGCAGTACGAGCTGACATCG
GCTACCCGCTTCGCCCAACTGTTGATTACCTGGCGCTTTTTGGAGCAAATCAACTATTTGCTTCAAAAAAACCGATAG

Upstream 100 bases:

>100_bases
AACACCCATTCGTCTTTGTGTGCTATTTATCTTGGGGGGAACCCACGGCGATCGGTGATTTTTTATCAACGCAATCGAAG
CCAATCTGGACGCCGCCGGA

Downstream 100 bases:

>100_bases
TGCACTCTTAATCTTTTAAGACAAGGAGTTCTTGGCATGCTGATTACATCGATCGAAGCGCACGAAATTCTCGATTCACG
GGGCAATCCGACCGTCGAAG

Product: phosphoribulokinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
METLTATETQPMTNSVQFVCATARQQLKQLRSPIIVGVAGDSGSGKTTYSNGIRRLLGSDLVSTLCTDGYHKEDREQRQI
SGRLPLDPAANHLDRLAEHLKALKQGKAVPIPVYNHGSGKFEQPENFVPTPIVVVEGLHTLYPELIPYLDFSLYVDPDHP
VKWQWKWERDLKRRGHKAEQLEQEMLQREAAFKRWIDFQKIDANVVIKIFHSQLQCLAPHQFTGILPNPCYKVELILQPA
PVPLPTLPLPFDLAAMLAVDQPPFMLAAVPYRYWGRSAIAIHLDGVLSQKTIAGLEDYIVNYTGIPTDEAIPEEQYELTS
ATRFAQLLITWRFLEQINYLLQKNR

Sequences:

>Translated_345_residues
METLTATETQPMTNSVQFVCATARQQLKQLRSPIIVGVAGDSGSGKTTYSNGIRRLLGSDLVSTLCTDGYHKEDREQRQI
SGRLPLDPAANHLDRLAEHLKALKQGKAVPIPVYNHGSGKFEQPENFVPTPIVVVEGLHTLYPELIPYLDFSLYVDPDHP
VKWQWKWERDLKRRGHKAEQLEQEMLQREAAFKRWIDFQKIDANVVIKIFHSQLQCLAPHQFTGILPNPCYKVELILQPA
PVPLPTLPLPFDLAAMLAVDQPPFMLAAVPYRYWGRSAIAIHLDGVLSQKTIAGLEDYIVNYTGIPTDEAIPEEQYELTS
ATRFAQLLITWRFLEQINYLLQKNR
>Mature_345_residues
METLTATETQPMTNSVQFVCATARQQLKQLRSPIIVGVAGDSGSGKTTYSNGIRRLLGSDLVSTLCTDGYHKEDREQRQI
SGRLPLDPAANHLDRLAEHLKALKQGKAVPIPVYNHGSGKFEQPENFVPTPIVVVEGLHTLYPELIPYLDFSLYVDPDHP
VKWQWKWERDLKRRGHKAEQLEQEMLQREAAFKRWIDFQKIDANVVIKIFHSQLQCLAPHQFTGILPNPCYKVELILQPA
PVPLPTLPLPFDLAAMLAVDQPPFMLAAVPYRYWGRSAIAIHLDGVLSQKTIAGLEDYIVNYTGIPTDEAIPEEQYELTS
ATRFAQLLITWRFLEQINYLLQKNR

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Escherichia coli, GI87082034, Length=157, Percent_Identity=28.0254777070064, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17539892, Length=176, Percent_Identity=30.1136363636364, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539894, Length=180, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550449, Length=161, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573516, Length=161, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573514, Length=161, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573512, Length=161, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 39174; Mature: 39174

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLTATETQPMTNSVQFVCATARQQLKQLRSPIIVGVAGDSGSGKTTYSNGIRRLLGSD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
LVSTLCTDGYHKEDREQRQISGRLPLDPAANHLDRLAEHLKALKQGKAVPIPVYNHGSGK
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FEQPENFVPTPIVVVEGLHTLYPELIPYLDFSLYVDPDHPVKWQWKWERDLKRRGHKAEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEHHHHHHHCCCHHHH
LEQEMLQREAAFKRWIDFQKIDANVVIKIFHSQLQCLAPHQFTGILPNPCYKVELILQPA
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECC
PVPLPTLPLPFDLAAMLAVDQPPFMLAAVPYRYWGRSAIAIHLDGVLSQKTIAGLEDYIV
CCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
NYTGIPTDEAIPEEQYELTSATRFAQLLITWRFLEQINYLLQKNR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METLTATETQPMTNSVQFVCATARQQLKQLRSPIIVGVAGDSGSGKTTYSNGIRRLLGSD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
LVSTLCTDGYHKEDREQRQISGRLPLDPAANHLDRLAEHLKALKQGKAVPIPVYNHGSGK
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FEQPENFVPTPIVVVEGLHTLYPELIPYLDFSLYVDPDHPVKWQWKWERDLKRRGHKAEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEHHHHHHHCCCHHHH
LEQEMLQREAAFKRWIDFQKIDANVVIKIFHSQLQCLAPHQFTGILPNPCYKVELILQPA
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECC
PVPLPTLPLPFDLAAMLAVDQPPFMLAAVPYRYWGRSAIAIHLDGVLSQKTIAGLEDYIV
CCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHCCCEEEEEEECCHHHHHHHHHHHHHHH
NYTGIPTDEAIPEEQYELTSATRFAQLLITWRFLEQINYLLQKNR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]