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The map label for this gene is 37521188

Identifier: 37521188

GI number: 37521188

Start: 1735391

End: 1736302

Strand: Reverse

Name: 37521188

Synonym: gll1619

Alternate gene names: NA

Gene position: 1736302-1735391 (Counterclockwise)

Preceding gene: 37521189

Following gene: 37521187

Centisome position: 37.27

GC content: 66.34

Gene sequence:

>912_bases
GTGGAACTGCCCTTCGTTTACAGCCCCCGCTACGAGGCGAACCTGCCCCCCGCCCACCGCTTTCCAATGGGCAAATTCAG
CCGCCTCCACCACTATTTGCTCAACCAGGGCGTCGCCCGGCCGGAGCAATTTTGGGAGCCGGAGCGGGCCGGTTGGGAGT
GGCTGACACTGGTGCACGCGCCGCGCTATGTCGCGGATTTTTGCGCAGGGATCTTAAGCGCTCAGGAATTTCGGCGCATT
GGCCTACCTTGGAGTCCGGCTCTAGTCGAGCGCACCTGCACCGCCGTGGGCGGCACGATCTTGACCGCCCGGCTCGCCCT
CAGGCACGGTCTCGCCTGCAACACCTGCGGCGGCACCCACCACGCCTTTCCGGACTTCGGTTCCGGCTTTTGCATCTTCA
ACGACCTGGCGGTGAGCGCCCGGGTGCTGTTGGCCGAGGGACAGGTGCGCCGCGTGCTCATCGTCGATCTTGATGTGCAC
CAGGGCGACGGCACCGCCTGGATTTTCGCGGACGAACCCGGGGTGTTCACCTTCTCGATGCACTGCGAACAAAATTTTCC
CGGCCGCAAGCAGCGCAGCGACCTGGACGTTCCGCTGCCCATCGGGTTGGACGACGATACTTACCTGCGCGTCCTGAACG
AGCACCTGCCGGGGCTCATCGAGACCGTCCGCCCCGACCTGGTGCTCTACGACGCCGGGGTCGATCCCCACCGCAGCGAC
AAACTGGGCAAGCTCGCCCTCACCGACCGGGGATTGTTCGAGCGCGACCGCGCGGTGCTGGGCCTCTGTCTGAAGCGAGG
CATACCGGTGGCAGCCGTCATCGGCGGCGGCTACGACAACAATCTCGACGCGCTGGTGGCGCGGCACGCCCTGCTGCACC
GGGCCGCCGCCGAGGTTTATCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
AACGACGACGACGGCAACTTCAAACCGGTGCTGCGGGCCATCTTCGAGATGTCCGACGAAATGAACGAGCCTGAAATCAT
CGGCGATTGAGCCGTTCGGC

Downstream 100 bases:

>100_bases
GCGGCATTGCCGTAAAGAAAGCTGCTACATATTCCAAGGTCGATCGGCAAAACACCATCCGGAGATTTGCAGTCATACCG
ACTTTTTACCCACAAAAAGG

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MELPFVYSPRYEANLPPAHRFPMGKFSRLHHYLLNQGVARPEQFWEPERAGWEWLTLVHAPRYVADFCAGILSAQEFRRI
GLPWSPALVERTCTAVGGTILTARLALRHGLACNTCGGTHHAFPDFGSGFCIFNDLAVSARVLLAEGQVRRVLIVDLDVH
QGDGTAWIFADEPGVFTFSMHCEQNFPGRKQRSDLDVPLPIGLDDDTYLRVLNEHLPGLIETVRPDLVLYDAGVDPHRSD
KLGKLALTDRGLFERDRAVLGLCLKRGIPVAAVIGGGYDNNLDALVARHALLHRAAAEVYRRA

Sequences:

>Translated_303_residues
MELPFVYSPRYEANLPPAHRFPMGKFSRLHHYLLNQGVARPEQFWEPERAGWEWLTLVHAPRYVADFCAGILSAQEFRRI
GLPWSPALVERTCTAVGGTILTARLALRHGLACNTCGGTHHAFPDFGSGFCIFNDLAVSARVLLAEGQVRRVLIVDLDVH
QGDGTAWIFADEPGVFTFSMHCEQNFPGRKQRSDLDVPLPIGLDDDTYLRVLNEHLPGLIETVRPDLVLYDAGVDPHRSD
KLGKLALTDRGLFERDRAVLGLCLKRGIPVAAVIGGGYDNNLDALVARHALLHRAAAEVYRRA
>Mature_303_residues
MELPFVYSPRYEANLPPAHRFPMGKFSRLHHYLLNQGVARPEQFWEPERAGWEWLTLVHAPRYVADFCAGILSAQEFRRI
GLPWSPALVERTCTAVGGTILTARLALRHGLACNTCGGTHHAFPDFGSGFCIFNDLAVSARVLLAEGQVRRVLIVDLDVH
QGDGTAWIFADEPGVFTFSMHCEQNFPGRKQRSDLDVPLPIGLDDDTYLRVLNEHLPGLIETVRPDLVLYDAGVDPHRSD
KLGKLALTDRGLFERDRAVLGLCLKRGIPVAAVIGGGYDNNLDALVARHALLHRAAAEVYRRA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=301, Percent_Identity=30.8970099667774, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI209862883, Length=281, Percent_Identity=29.1814946619217, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI13128860, Length=272, Percent_Identity=28.6764705882353, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI293336691, Length=256, Percent_Identity=29.296875, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI8923769, Length=301, Percent_Identity=26.9102990033223, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI13128864, Length=295, Percent_Identity=31.1864406779661, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13128862, Length=274, Percent_Identity=28.4671532846715, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI20070354, Length=256, Percent_Identity=28.90625, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI262073092, Length=235, Percent_Identity=27.2340425531915, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI62750349, Length=193, Percent_Identity=31.6062176165803, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI62750347, Length=193, Percent_Identity=31.6062176165803, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI17158039, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795204, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795202, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI169234807, Length=150, Percent_Identity=32.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI148539870, Length=150, Percent_Identity=32.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI153085395, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI262073088, Length=176, Percent_Identity=29.5454545454545, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193207430, Length=305, Percent_Identity=31.8032786885246, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537347, Length=272, Percent_Identity=32.7205882352941, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17508561, Length=276, Percent_Identity=29.7101449275362, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561978, Length=271, Percent_Identity=29.8892988929889, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534739, Length=200, Percent_Identity=30.5, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193209491, Length=299, Percent_Identity=25.0836120401338, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=145, Percent_Identity=33.1034482758621, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17540332, Length=145, Percent_Identity=33.1034482758621, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=30.6818181818182, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=312, Percent_Identity=28.8461538461538, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323999, Length=272, Percent_Identity=28.3088235294118, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=216, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649807, Length=291, Percent_Identity=31.6151202749141, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24657891, Length=287, Percent_Identity=31.0104529616725, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644244, Length=278, Percent_Identity=26.6187050359712, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24642144, Length=209, Percent_Identity=31.1004784688995, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642146, Length=209, Percent_Identity=31.1004784688995, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642142, Length=209, Percent_Identity=31.1004784688995, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360899, Length=208, Percent_Identity=30.2884615384615, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360799, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281360801, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641720, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33678; Mature: 33678

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPFVYSPRYEANLPPAHRFPMGKFSRLHHYLLNQGVARPEQFWEPERAGWEWLTLVHA
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEHHC
PRYVADFCAGILSAQEFRRIGLPWSPALVERTCTAVGGTILTARLALRHGLACNTCGGTH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
HAFPDFGSGFCIFNDLAVSARVLLAEGQVRRVLIVDLDVHQGDGTAWIFADEPGVFTFSM
CCCCCCCCCEEEEEHHHHHHEEEEECCCEEEEEEEEEEEECCCCEEEEEECCCCEEEEEE
HCEQNFPGRKQRSDLDVPLPIGLDDDTYLRVLNEHLPGLIETVRPDLVLYDAGVDPHRSD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCC
KLGKLALTDRGLFERDRAVLGLCLKRGIPVAAVIGGGYDNNLDALVARHALLHRAAAEVY
CCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RRA
HCC
>Mature Secondary Structure
MELPFVYSPRYEANLPPAHRFPMGKFSRLHHYLLNQGVARPEQFWEPERAGWEWLTLVHA
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEHHC
PRYVADFCAGILSAQEFRRIGLPWSPALVERTCTAVGGTILTARLALRHGLACNTCGGTH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
HAFPDFGSGFCIFNDLAVSARVLLAEGQVRRVLIVDLDVHQGDGTAWIFADEPGVFTFSM
CCCCCCCCCEEEEEHHHHHHEEEEECCCEEEEEEEEEEEECCCCEEEEEECCCCEEEEEE
HCEQNFPGRKQRSDLDVPLPIGLDDDTYLRVLNEHLPGLIETVRPDLVLYDAGVDPHRSD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCC
KLGKLALTDRGLFERDRAVLGLCLKRGIPVAAVIGGGYDNNLDALVARHALLHRAAAEVY
CCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RRA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]