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The map label for this gene is tal

Identifier: 37521166

GI number: 37521166

Start: 1713857

End: 1715026

Strand: Reverse

Name: tal

Synonym: gll1597

Alternate gene names: 37521166

Gene position: 1715026-1713857 (Counterclockwise)

Preceding gene: 37521167

Following gene: 37521165

Centisome position: 36.81

GC content: 62.39

Gene sequence:

>1170_bases
ATGACCGGAAGCCTACTTGACCAACTGCGGCAGATGACCATCGTCGTCGCCGACACCGGCGACATCCAGGCCATTGAGCA
GTTCACACCGCGCGACGCCACCACCAATCCTTCGCTGATCACCGCCGCCGCCCAGATGCCGCAGTATCAGCAAATCGTAG
ACGACACCCTCAAGCAGGCGCGCGCGGAGCTGGGTCCCGAGGCGAAGGCCGCGGCGGTCGCCACCCTCGCCTTCGACCGG
CTGGCGGTGGCCTTTGGCCTCAAGATCCTGGCCATCGTCCCCGGGCGGGTCTCGACCGAAGTCGACGCGCGCCTGTCCTA
CGACACCGAGGCGACGATCGAAAAGGGGCGCTCACTGATCGCCCAGTACGAAGCGGCGGGCATTTCCCGCGAGCGGGTGC
TCATCAAGATCGCTTCGACCTGGGAGGGTATCCGCGCCGCCGAAATTCTTGAGGACGAAGGCATCCACTGCAACCTGACG
TTGCTGTTCGGTGTGCACCAGGCGATCGCCTGCGCCGAGGCGGGGGTGACCCTCATCTCACCTTTCGTCGGTCGCATCCT
CGACTGGTACAAAAAAGAAACCGGCCGCGATTACGAGCCCCACGAAGATCCGGGCGTGGTCTCGGTGACGACCATTTACA
ACTACTACAAAAAGTTCGGCTACCAAACCCAGGTGATGGGGGCGAGCTTCCGCAACATCGGCGAAATCGTCGAACTGGCC
GGCTGCGATTTGCTCACGATCTCTCCAAAGCTTCTCGAACAACTGCAGGCGACCGACGCAGAACTCGTCCGCAAGCTGGA
TCCGGACCAAGCCGCTGGCCTGGAGATCGAAAAGATCGACATGGACCAGGCGACCTTCGAGAAGAGGCACGCCGAAGACC
GCATGGCTTCTGAGAAGCTCGACGAGGGCATCAAGGGCTTCACCAACGCCCTGGTGGCCCTGGAGAAGCTGCTCGCCGAC
CGTCTGGCGCGGCTGGAGGGTGAAGTGGCCCTCAACCAGGCCTTCGAAAGCATCTTCCGCACTTTTGATCTCGACGGCGA
CGGGTTTATCACCCGCGAGGAGTGGATGGGCACCGACGCGGTTTTTGATGCCATCGACCTCAACCATGACGGCAAGATCA
CAGCGGAGGAATTGGGGGCCGGGATCGGGGCCGTCTCGAAACTGGCGTAG

Upstream 100 bases:

>100_bases
GGAGGGGGGCTGGTATTTTGTTAGGGCTGTCCTCCGGCAAGAGTCTTGGTCCAGGGAAAGCTTGAGTTCAGAGCAAACCC
TTAAATTGAAGGAGACGGGC

Downstream 100 bases:

>100_bases
GTGATGTCTCCAAAGCAGTCCGACTGTGATAGCCACCACGGAGCGAGGGTCTTTCCATGGCTCACCTCATCCTTATCCGG
CACGGCCAGAGTCTTTGGAA

Product: transaldolase/EF-hand domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTGSLLDQLRQMTIVVADTGDIQAIEQFTPRDATTNPSLITAAAQMPQYQQIVDDTLKQARAELGPEAKAAAVATLAFDR
LAVAFGLKILAIVPGRVSTEVDARLSYDTEATIEKGRSLIAQYEAAGISRERVLIKIASTWEGIRAAEILEDEGIHCNLT
LLFGVHQAIACAEAGVTLISPFVGRILDWYKKETGRDYEPHEDPGVVSVTTIYNYYKKFGYQTQVMGASFRNIGEIVELA
GCDLLTISPKLLEQLQATDAELVRKLDPDQAAGLEIEKIDMDQATFEKRHAEDRMASEKLDEGIKGFTNALVALEKLLAD
RLARLEGEVALNQAFESIFRTFDLDGDGFITREEWMGTDAVFDAIDLNHDGKITAEELGAGIGAVSKLA

Sequences:

>Translated_389_residues
MTGSLLDQLRQMTIVVADTGDIQAIEQFTPRDATTNPSLITAAAQMPQYQQIVDDTLKQARAELGPEAKAAAVATLAFDR
LAVAFGLKILAIVPGRVSTEVDARLSYDTEATIEKGRSLIAQYEAAGISRERVLIKIASTWEGIRAAEILEDEGIHCNLT
LLFGVHQAIACAEAGVTLISPFVGRILDWYKKETGRDYEPHEDPGVVSVTTIYNYYKKFGYQTQVMGASFRNIGEIVELA
GCDLLTISPKLLEQLQATDAELVRKLDPDQAAGLEIEKIDMDQATFEKRHAEDRMASEKLDEGIKGFTNALVALEKLLAD
RLARLEGEVALNQAFESIFRTFDLDGDGFITREEWMGTDAVFDAIDLNHDGKITAEELGAGIGAVSKLA
>Mature_388_residues
TGSLLDQLRQMTIVVADTGDIQAIEQFTPRDATTNPSLITAAAQMPQYQQIVDDTLKQARAELGPEAKAAAVATLAFDRL
AVAFGLKILAIVPGRVSTEVDARLSYDTEATIEKGRSLIAQYEAAGISRERVLIKIASTWEGIRAAEILEDEGIHCNLTL
LFGVHQAIACAEAGVTLISPFVGRILDWYKKETGRDYEPHEDPGVVSVTTIYNYYKKFGYQTQVMGASFRNIGEIVELAG
CDLLTISPKLLEQLQATDAELVRKLDPDQAAGLEIEKIDMDQATFEKRHAEDRMASEKLDEGIKGFTNALVALEKLLADR
LARLEGEVALNQAFESIFRTFDLDGDGFITREEWMGTDAVFDAIDLNHDGKITAEELGAGIGAVSKLA

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 EF-hand domains

Homologues:

Organism=Homo sapiens, GI5803187, Length=326, Percent_Identity=57.0552147239264, Blast_Score=365, Evalue=1e-101,
Organism=Escherichia coli, GI1786189, Length=318, Percent_Identity=57.2327044025157, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1788807, Length=318, Percent_Identity=54.0880503144654, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI25153750, Length=321, Percent_Identity=55.1401869158878, Blast_Score=346, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=53.9393939393939, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17570473, Length=93, Percent_Identity=46.2365591397849, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323386, Length=324, Percent_Identity=56.4814814814815, Blast_Score=308, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6321480, Length=323, Percent_Identity=49.5356037151703, Blast_Score=308, Evalue=1e-84,
Organism=Drosophila melanogaster, GI45549185, Length=321, Percent_Identity=56.0747663551402, Blast_Score=358, Evalue=3e-99,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TAL_GLOVI (Q7NK81)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924543.1
- ProteinModelPortal:   Q7NK81
- SMR:   Q7NK81
- GeneID:   2598563
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1597
- NMPDR:   fig|251221.1.peg.1597
- HOGENOM:   HBG286747
- OMA:   EKERINC
- ProtClustDB:   PRK12309
- BioCyc:   GVIO251221:GLL1597-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR011992
- InterPro:   IPR018247
- InterPro:   IPR018249
- InterPro:   IPR002048
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:1.10.238.10
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- SMART:   SM00054
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 42514; Mature: 42383

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00018 EF_HAND_1; PS50222 EF_HAND_2; PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSLLDQLRQMTIVVADTGDIQAIEQFTPRDATTNPSLITAAAQMPQYQQIVDDTLKQA
CCCHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
RAELGPEAKAAAVATLAFDRLAVAFGLKILAIVPGRVSTEVDARLSYDTEATIEKGRSLI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHCEECCCCHHHHHHHHHHH
AQYEAAGISRERVLIKIASTWEGIRAAEILEDEGIHCNLTLLFGVHQAIACAEAGVTLIS
HHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHH
PFVGRILDWYKKETGRDYEPHEDPGVVSVTTIYNYYKKFGYQTQVMGASFRNIGEIVELA
HHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GCDLLTISPKLLEQLQATDAELVRKLDPDQAAGLEIEKIDMDQATFEKRHAEDRMASEKL
CCCEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DEGIKGFTNALVALEKLLADRLARLEGEVALNQAFESIFRTFDLDGDGFITREEWMGTDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHH
VFDAIDLNHDGKITAEELGAGIGAVSKLA
HHHHHCCCCCCCEEHHHHCCCCCHHHHCC
>Mature Secondary Structure 
TGSLLDQLRQMTIVVADTGDIQAIEQFTPRDATTNPSLITAAAQMPQYQQIVDDTLKQA
CCHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
RAELGPEAKAAAVATLAFDRLAVAFGLKILAIVPGRVSTEVDARLSYDTEATIEKGRSLI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHCEECCCCHHHHHHHHHHH
AQYEAAGISRERVLIKIASTWEGIRAAEILEDEGIHCNLTLLFGVHQAIACAEAGVTLIS
HHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHH
PFVGRILDWYKKETGRDYEPHEDPGVVSVTTIYNYYKKFGYQTQVMGASFRNIGEIVELA
HHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GCDLLTISPKLLEQLQATDAELVRKLDPDQAAGLEIEKIDMDQATFEKRHAEDRMASEKL
CCCEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DEGIKGFTNALVALEKLLADRLARLEGEVALNQAFESIFRTFDLDGDGFITREEWMGTDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHH
VFDAIDLNHDGKITAEELGAGIGAVSKLA
HHHHHCCCCCCCEEHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292