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The map label for this gene is gpmA1

Identifier: 37521165

GI number: 37521165

Start: 1713102

End: 1713800

Strand: Reverse

Name: gpmA1

Synonym: gll1596

Alternate gene names: 37521165

Gene position: 1713800-1713102 (Counterclockwise)

Preceding gene: 37521166

Following gene: 37521164

Centisome position: 36.78

GC content: 61.23

Gene sequence:

>699_bases
ATGGCTCACCTCATCCTTATCCGGCACGGCCAGAGTCTTTGGAACGCCGCCAACAAATTTACCGGTTGGGTGGACGTTCC
CTTGAGTGAGCGCGGCCGGGCGGAGGCGACGATCGCTTCTTGCAAACTTCGGGATTATCGGGTGAACGTCTGCTTCACCA
GCATGCTGATGCGCGCCATCGAAACAGCGGTGATTACCCTGACCGAGTGCGACGATATCTGCGGCGGCAAAATCCCAATC
ATCAAACACGAAGCCGACGACGAGAACTGGCACGGCTGGGACAACTACGACGGCGACCCGGCGGCGGAGTTGCCCATCTA
TCCCACCGCGACCCTGGACGAGCGCTACTACGGCGATCTGCAAGGCCTCGACAAAGCCGAGACGACCGCGAAGTACGGCA
AGGAGCAAGTCCAGATCTGGCGGCGCTCCTACTCGGTGCGCCCCCCCGGCGGCGAGAGCCTGGAGGACACGCGCAAGCGC
GTCTACCCCTATTTCACCAACCGTATCCTGGGCCATATCAAGCAGGGGGACAACGTGCTGGTGGCTGCCCACGGCAACTC
CCTGCGCTCGATCATCATGATTCTTGAAACCCTCAGCGAGGAAGAAGTGCCCAAGGTGGAGCTGGCCACCGGGGTGCCGA
TCGTCTACGAACTCGACAAAGCGGCCCACATGCTCAGCAAGGCCGTGCTCACCAACTGA

Upstream 100 bases:

>100_bases
AGGAATTGGGGGCCGGGATCGGGGCCGTCTCGAAACTGGCGTAGGTGATGTCTCCAAAGCAGTCCGACTGTGATAGCCAC
CACGGAGCGAGGGTCTTTCC

Downstream 100 bases:

>100_bases
CCCCCCACCACCCACCATGGCAATCACCATCGAAGAGAAAGCTCCCCGCAAGCTCAGCGAAGCGGATCTGCGGCCGCGCG
GCCAAGTGCATCCGAGCCCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAHLILIRHGQSLWNAANKFTGWVDVPLSERGRAEATIASCKLRDYRVNVCFTSMLMRAIETAVITLTECDDICGGKIPI
IKHEADDENWHGWDNYDGDPAAELPIYPTATLDERYYGDLQGLDKAETTAKYGKEQVQIWRRSYSVRPPGGESLEDTRKR
VYPYFTNRILGHIKQGDNVLVAAHGNSLRSIIMILETLSEEEVPKVELATGVPIVYELDKAAHMLSKAVLTN

Sequences:

>Translated_232_residues
MAHLILIRHGQSLWNAANKFTGWVDVPLSERGRAEATIASCKLRDYRVNVCFTSMLMRAIETAVITLTECDDICGGKIPI
IKHEADDENWHGWDNYDGDPAAELPIYPTATLDERYYGDLQGLDKAETTAKYGKEQVQIWRRSYSVRPPGGESLEDTRKR
VYPYFTNRILGHIKQGDNVLVAAHGNSLRSIIMILETLSEEEVPKVELATGVPIVYELDKAAHMLSKAVLTN
>Mature_231_residues
AHLILIRHGQSLWNAANKFTGWVDVPLSERGRAEATIASCKLRDYRVNVCFTSMLMRAIETAVITLTECDDICGGKIPII
KHEADDENWHGWDNYDGDPAAELPIYPTATLDERYYGDLQGLDKAETTAKYGKEQVQIWRRSYSVRPPGGESLEDTRKRV
YPYFTNRILGHIKQGDNVLVAAHGNSLRSIIMILETLSEEEVPKVELATGVPIVYELDKAAHMLSKAVLTN

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI4505753, Length=246, Percent_Identity=41.4634146341463, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI50593010, Length=246, Percent_Identity=37.8048780487805, Blast_Score=164, Evalue=5e-41,
Organism=Homo sapiens, GI71274132, Length=246, Percent_Identity=39.0243902439024, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI4502445, Length=248, Percent_Identity=31.8548387096774, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI40353764, Length=248, Percent_Identity=31.8548387096774, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI310129614, Length=145, Percent_Identity=42.7586206896552, Blast_Score=105, Evalue=3e-23,
Organism=Escherichia coli, GI1786970, Length=259, Percent_Identity=38.2239382239382, Blast_Score=167, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322697, Length=247, Percent_Identity=36.8421052631579, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=275, Percent_Identity=29.0909090909091, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324516, Length=273, Percent_Identity=25.6410256410256, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI85725270, Length=247, Percent_Identity=37.246963562753, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI85725272, Length=247, Percent_Identity=37.246963562753, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24650981, Length=247, Percent_Identity=37.246963562753, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24646216, Length=253, Percent_Identity=34.7826086956522, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28571817, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648979, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571815, Length=246, Percent_Identity=30.0813008130081, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA1_GLOVI (Q7NK82)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924542.1
- ProteinModelPortal:   Q7NK82
- SMR:   Q7NK82
- GeneID:   2598562
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1596
- NMPDR:   fig|251221.1.peg.1596
- HOGENOM:   HBG658938
- OMA:   IRTLWFV
- ProtClustDB:   PRK01112
- BioCyc:   GVIO251221:GLL1596-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 26061; Mature: 25930

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLILIRHGQSLWNAANKFTGWVDVPLSERGRAEATIASCKLRDYRVNVCFTSMLMRAI
CCEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCHHHHEEEEEEEEEEHHHHHHHHHHHH
ETAVITLTECDDICGGKIPIIKHEADDENWHGWDNYDGDPAAELPIYPTATLDERYYGDL
HHHEEEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCC
QGLDKAETTAKYGKEQVQIWRRSYSVRPPGGESLEDTRKRVYPYFTNRILGHIKQGDNVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VAAHGNSLRSIIMILETLSEEEVPKVELATGVPIVYELDKAAHMLSKAVLTN
EEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHLILIRHGQSLWNAANKFTGWVDVPLSERGRAEATIASCKLRDYRVNVCFTSMLMRAI
CEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCHHHHEEEEEEEEEEHHHHHHHHHHHH
ETAVITLTECDDICGGKIPIIKHEADDENWHGWDNYDGDPAAELPIYPTATLDERYYGDL
HHHEEEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCC
QGLDKAETTAKYGKEQVQIWRRSYSVRPPGGESLEDTRKRVYPYFTNRILGHIKQGDNVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VAAHGNSLRSIIMILETLSEEEVPKVELATGVPIVYELDKAAHMLSKAVLTN
EEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292