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The map label for this gene is glyQ

Identifier: 37521015

GI number: 37521015

Start: 1548691

End: 1549563

Strand: Direct

Name: glyQ

Synonym: gvip203

Alternate gene names: 37521015

Gene position: 1548691-1549563 (Clockwise)

Preceding gene: 37521013

Following gene: 37521016

Centisome position: 33.24

GC content: 55.56

Gene sequence:

>873_bases
ATGAACTTTCAGGACATGACCTTGTCGCTTCATCGGTTTTGGGAGGAGCAGGGATGTCTGATTGTTCAACCGTACGACGT
AGAAAAAGGCGCAGGCACGATGAATCCGCATACTTTTTTGCGGGCTATCGGACCTGAGCCCTGGAATGTTGCTTATATCG
AGCCGTGTCGGCGGCCCACCGATGGTCGCTACGCACAAAATCCCAATCGTCTTCAGCATTACTACCAGTATCAGGTGCTG
ATGAAGCCCTCCCCCGGCGACATTCAGGAGCGTTACCTGCGCTCGCTGGAGGTGCTGGGGATTCACCCCGAAAAACACGA
CGTCCGGTTTGTCGAAGACAACTGGGAATCGCCGACCCTCGGGGCCTGGGGGGTGGGCTGGGAAGTCTGGCTCGACGGCA
TGGAGGTGACGCAATTTACGTATTTCCAGCAGTGTGGAGGCATCGACTGCCGCCCGGTTTCCATCGAAATCACCTACGGC
ATTGAGCGACTGGCCATGTATCTGCAGGGTGTAGATTCGATTTTCGACATCGAATGGGGAGCTGGCCTCACCTACGGCCA
GGTCCACCGCGAAGGGGAAATCGAAAATTGCATCTATAATTTTGAACAGGCGAATCCGGAATTGCTGTTTACCCTTTTCA
AGCTCTACGAGCAGGAGGCTACGGCGCTTAGCGAGCGCCGACTGGTGCTTCCGGCGCTCGATTATGTCCTCAAGTGTTCC
CACACATTCAACTTGTTGGATGCGCGCGGTGTGATCGCCGTCACCGAGCGGACCGGCTATATCGGCCGGATACGCCACCT
GGCCAGGCGAATTGCGCAAGCCTACGCAAAGCAAAGAGAATCTCTGGGGTTTCCTCTGCTAAGCAAAACCTGA

Upstream 100 bases:

>100_bases
CGGCTTGTTAATTTTCTAGAAGCGATCCCGGCGATGGTGTAATGCGATACATCCATGCGCTAACCTTGTACAAAGAACGT
TTCGGGCTACGCCTTGCGAT

Downstream 100 bases:

>100_bases
CTTATACCTGCTTTTAGGAGTTTCCATGGTCGCTCAATACCGGCAAGATCGCGTGTCGATTTTCATCGACGGCAACAACA
TGTTTTACGCCCAGCGGTCG

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MNFQDMTLSLHRFWEEQGCLIVQPYDVEKGAGTMNPHTFLRAIGPEPWNVAYIEPCRRPTDGRYAQNPNRLQHYYQYQVL
MKPSPGDIQERYLRSLEVLGIHPEKHDVRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYG
IERLAMYLQGVDSIFDIEWGAGLTYGQVHREGEIENCIYNFEQANPELLFTLFKLYEQEATALSERRLVLPALDYVLKCS
HTFNLLDARGVIAVTERTGYIGRIRHLARRIAQAYAKQRESLGFPLLSKT

Sequences:

>Translated_290_residues
MNFQDMTLSLHRFWEEQGCLIVQPYDVEKGAGTMNPHTFLRAIGPEPWNVAYIEPCRRPTDGRYAQNPNRLQHYYQYQVL
MKPSPGDIQERYLRSLEVLGIHPEKHDVRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYG
IERLAMYLQGVDSIFDIEWGAGLTYGQVHREGEIENCIYNFEQANPELLFTLFKLYEQEATALSERRLVLPALDYVLKCS
HTFNLLDARGVIAVTERTGYIGRIRHLARRIAQAYAKQRESLGFPLLSKT
>Mature_290_residues
MNFQDMTLSLHRFWEEQGCLIVQPYDVEKGAGTMNPHTFLRAIGPEPWNVAYIEPCRRPTDGRYAQNPNRLQHYYQYQVL
MKPSPGDIQERYLRSLEVLGIHPEKHDVRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYG
IERLAMYLQGVDSIFDIEWGAGLTYGQVHREGEIENCIYNFEQANPELLFTLFKLYEQEATALSERRLVLPALDYVLKCS
HTFNLLDARGVIAVTERTGYIGRIRHLARRIAQAYAKQRESLGFPLLSKT

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=60.5442176870748, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_GLOVI (Q7NKN1)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924392.1
- HSSP:   Q9WY59
- ProteinModelPortal:   Q7NKN1
- SMR:   Q7NKN1
- GeneID:   2598715
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1446
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   GVIO251221:GLR1446-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33563; Mature: 33563

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQDMTLSLHRFWEEQGCLIVQPYDVEKGAGTMNPHTFLRAIGPEPWNVAYIEPCRRPT
CCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCC
DGRYAQNPNRLQHYYQYQVLMKPSPGDIQERYLRSLEVLGIHPEKHDVRFVEDNWESPTL
CCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYGIERLAMYLQGVDSIFDIEWG
CCCCCCHHHEECCCHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCHHEEECCC
AGLTYGQVHREGEIENCIYNFEQANPELLFTLFKLYEQEATALSERRLVLPALDYVLKCS
CCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
HTFNLLDARGVIAVTERTGYIGRIRHLARRIAQAYAKQRESLGFPLLSKT
CHHEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNFQDMTLSLHRFWEEQGCLIVQPYDVEKGAGTMNPHTFLRAIGPEPWNVAYIEPCRRPT
CCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCC
DGRYAQNPNRLQHYYQYQVLMKPSPGDIQERYLRSLEVLGIHPEKHDVRFVEDNWESPTL
CCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYGIERLAMYLQGVDSIFDIEWG
CCCCCCHHHEECCCHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCHHEEECCC
AGLTYGQVHREGEIENCIYNFEQANPELLFTLFKLYEQEATALSERRLVLPALDYVLKCS
CCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
HTFNLLDARGVIAVTERTGYIGRIRHLARRIAQAYAKQRESLGFPLLSKT
CHHEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292