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The map label for this gene is prpC [H]

Identifier: 37520974

GI number: 37520974

Start: 1505437

End: 1506804

Strand: Reverse

Name: prpC [H]

Synonym: gll1405

Alternate gene names: 37520974

Gene position: 1506804-1505437 (Counterclockwise)

Preceding gene: 37520975

Following gene: 37520973

Centisome position: 32.34

GC content: 68.42

Gene sequence:

>1368_bases
ATGCACTATCTGGTCACCGGCAATCGCCAGGCCCTCGACCGGCGCTACCGGGTGGTCGGCCAGTCCCCGGCAATCGCCCG
GGATCTGCTGCCGGACCAGCCCACCGCCGCCCCCGCGGGCCTGCCTGCCGGTTGCCGCCCTTACCAGAGGCTGCACCACT
TTCGCTGGGCGATCCCCGAGATTCACACCTGCATGGCGGCCCCAAATGGCGGCGAACCGTGCGTGCTGTTGGCGCGCGGG
CCGCTCGCAGCCGACGGCACCCCCTGGCCGACATTGCGCCAGGGCTGGCCCGCCGCCCCACCGTTGCAGCAGATTGGCTG
GCTGGTTCAACTGGCCCGCCTCTGGGAACCCTGTGTGCAGGAGGGGGTAGCCTCTTCGCTGCTTGCCCCCGACAACATCG
GCGTACTCGGCTGGCAGGCTTGCCTGTTTTATTTGAGCGGCGACCCGGCGCCGCCGCCGCTCGCGGCCTTGGGGCAAAGC
TGGCAGAGCCTGATCCCCCTCAGCCCGCCGCTCGCCGCAATCGTCGGGGCACTCTGCCTGGGCCGAATCGCCCGCGTCGA
GGAGCTGTCCGCCGCCCTCGAAAATCTCGCCGCCGCCAACCCTGGCCGCGGTCCGGCGGGCGTGCTGGGTGCGACCCACC
CGGGCAGCCGCAAGGCCAACGAGGACTGCTTCATCCACGATCCGCCCGGCACCTACGGCATCGTCTGCGACGGCATGGGC
GGGCACGAAGGCGGCGCGGTGGCAAGCCGCCTGGCTCTGGATCTGCTCGATCGCGAACTGCAGCAACTCAGCCGTCAGAC
CCAGCCCCTGCCGCCTTTGCAGGTGCGCCGGGGCATGGCGTTGGCCCTCTACCGCGCCAACCAGTTGCTCTTGGAGACCA
ACCGCCGCCAGGGACGCCAGCGCCGGCACCAGATGGGTACGACCGTCGTCGCCTACTGCCTGACGGGCAGCCTGCTGCAC
ATTGCCCACGTCGGCGACAGCCGCATCTACCTCATCGACCGGCACCACTGCCAGCAGCTCACCGTCGATGACGACGTGGC
CAACCAGGAGGTGAGTCTGGCGCGCACCACCAGCAGTGCTGTGCTGCGCATGGACGGCAGCGGCCATCTCACCCAGGCGC
TCGGGGTGATCGCCATGGAGGCTTTGCAGCCCACAGTCCAGACCTTTGTGCTGCCTGAAGACTGTCTGGTGCTGCTGTGC
AGCGATGGGCTGTGCGACGGGTCGCTTGTCGAGCGCTGCTGGCAGACGGTGCTCCTACCCATGCTCACCGGCGATCTCGC
CGCCGGGGCGCGGCAGTTGATCGATTTGGCTCTCCAGGAACTGGGGCACGACAATATAACGTTTATTCTTTTGAAGTACG
CCGCCTAA

Upstream 100 bases:

>100_bases
GGAACGCGCTTTCGCCGTAAGCTCAAAGCGGGCGACACCATCGCCCTCGGCAAAGCCAACAAGATGAGCTTCCGCTTCGA
AATCGAAGAGTAAACCGCCC

Downstream 100 bases:

>100_bases
TTTTGCTGCCGCCGTTGAACGTCGTCGAGTTGGACCAGGTCGTCAAGTGCTTCAGTGAGCCCGGCGGCAAGCCACTGCGC
GCCGTGGACGCGGTGAGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MHYLVTGNRQALDRRYRVVGQSPAIARDLLPDQPTAAPAGLPAGCRPYQRLHHFRWAIPEIHTCMAAPNGGEPCVLLARG
PLAADGTPWPTLRQGWPAAPPLQQIGWLVQLARLWEPCVQEGVASSLLAPDNIGVLGWQACLFYLSGDPAPPPLAALGQS
WQSLIPLSPPLAAIVGALCLGRIARVEELSAALENLAAANPGRGPAGVLGATHPGSRKANEDCFIHDPPGTYGIVCDGMG
GHEGGAVASRLALDLLDRELQQLSRQTQPLPPLQVRRGMALALYRANQLLLETNRRQGRQRRHQMGTTVVAYCLTGSLLH
IAHVGDSRIYLIDRHHCQQLTVDDDVANQEVSLARTTSSAVLRMDGSGHLTQALGVIAMEALQPTVQTFVLPEDCLVLLC
SDGLCDGSLVERCWQTVLLPMLTGDLAAGARQLIDLALQELGHDNITFILLKYAA

Sequences:

>Translated_455_residues
MHYLVTGNRQALDRRYRVVGQSPAIARDLLPDQPTAAPAGLPAGCRPYQRLHHFRWAIPEIHTCMAAPNGGEPCVLLARG
PLAADGTPWPTLRQGWPAAPPLQQIGWLVQLARLWEPCVQEGVASSLLAPDNIGVLGWQACLFYLSGDPAPPPLAALGQS
WQSLIPLSPPLAAIVGALCLGRIARVEELSAALENLAAANPGRGPAGVLGATHPGSRKANEDCFIHDPPGTYGIVCDGMG
GHEGGAVASRLALDLLDRELQQLSRQTQPLPPLQVRRGMALALYRANQLLLETNRRQGRQRRHQMGTTVVAYCLTGSLLH
IAHVGDSRIYLIDRHHCQQLTVDDDVANQEVSLARTTSSAVLRMDGSGHLTQALGVIAMEALQPTVQTFVLPEDCLVLLC
SDGLCDGSLVERCWQTVLLPMLTGDLAAGARQLIDLALQELGHDNITFILLKYAA
>Mature_455_residues
MHYLVTGNRQALDRRYRVVGQSPAIARDLLPDQPTAAPAGLPAGCRPYQRLHHFRWAIPEIHTCMAAPNGGEPCVLLARG
PLAADGTPWPTLRQGWPAAPPLQQIGWLVQLARLWEPCVQEGVASSLLAPDNIGVLGWQACLFYLSGDPAPPPLAALGQS
WQSLIPLSPPLAAIVGALCLGRIARVEELSAALENLAAANPGRGPAGVLGATHPGSRKANEDCFIHDPPGTYGIVCDGMG
GHEGGAVASRLALDLLDRELQQLSRQTQPLPPLQVRRGMALALYRANQLLLETNRRQGRQRRHQMGTTVVAYCLTGSLLH
IAHVGDSRIYLIDRHHCQQLTVDDDVANQEVSLARTTSSAVLRMDGSGHLTQALGVIAMEALQPTVQTFVLPEDCLVLLC
SDGLCDGSLVERCWQTVLLPMLTGDLAAGARQLIDLALQELGHDNITFILLKYAA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 48898; Mature: 48898

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYLVTGNRQALDRRYRVVGQSPAIARDLLPDQPTAAPAGLPAGCRPYQRLHHFRWAIPE
CCEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
IHTCMAAPNGGEPCVLLARGPLAADGTPWPTLRQGWPAAPPLQQIGWLVQLARLWEPCVQ
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGVASSLLAPDNIGVLGWQACLFYLSGDPAPPPLAALGQSWQSLIPLSPPLAAIVGALCL
HHHHHHCCCCCCCCHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
GRIARVEELSAALENLAAANPGRGPAGVLGATHPGSRKANEDCFIHDPPGTYGIVCDGMG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCC
GHEGGAVASRLALDLLDRELQQLSRQTQPLPPLQVRRGMALALYRANQLLLETNRRQGRQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHH
RRHQMGTTVVAYCLTGSLLHIAHVGDSRIYLIDRHHCQQLTVDDDVANQEVSLARTTSSA
HHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHEEECCCE
VLRMDGSGHLTQALGVIAMEALQPTVQTFVLPEDCLVLLCSDGLCDGSLVERCWQTVLLP
EEEECCCCHHHHHHHHHHHHHHHHHHHHEECCHHHEEEEECCCCCCCHHHHHHHHHHHHH
MLTGDLAAGARQLIDLALQELGHDNITFILLKYAA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MHYLVTGNRQALDRRYRVVGQSPAIARDLLPDQPTAAPAGLPAGCRPYQRLHHFRWAIPE
CCEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
IHTCMAAPNGGEPCVLLARGPLAADGTPWPTLRQGWPAAPPLQQIGWLVQLARLWEPCVQ
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGVASSLLAPDNIGVLGWQACLFYLSGDPAPPPLAALGQSWQSLIPLSPPLAAIVGALCL
HHHHHHCCCCCCCCHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
GRIARVEELSAALENLAAANPGRGPAGVLGATHPGSRKANEDCFIHDPPGTYGIVCDGMG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCC
GHEGGAVASRLALDLLDRELQQLSRQTQPLPPLQVRRGMALALYRANQLLLETNRRQGRQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHH
RRHQMGTTVVAYCLTGSLLHIAHVGDSRIYLIDRHHCQQLTVDDDVANQEVSLARTTSSA
HHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHEEECCCE
VLRMDGSGHLTQALGVIAMEALQPTVQTFVLPEDCLVLLCSDGLCDGSLVERCWQTVLLP
EEEECCCCHHHHHHHHHHHHHHHHHHHHEECCHHHEEEEECCCCCCCHHHHHHHHHHHHH
MLTGDLAAGARQLIDLALQELGHDNITFILLKYAA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]