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The map label for this gene is 37520959

Identifier: 37520959

GI number: 37520959

Start: 1493005

End: 1494189

Strand: Direct

Name: 37520959

Synonym: glr1390

Alternate gene names: NA

Gene position: 1493005-1494189 (Clockwise)

Preceding gene: 37520958

Following gene: 37520964

Centisome position: 32.05

GC content: 62.62

Gene sequence:

>1185_bases
ATGCGCATTATCTTGATGACCGGCAAAGGTGGGGTAGGCAAGACCAGCATGGCCGCCGCCACCGGGCTGCGTTGCGCCGA
GTTGGGCTATCGGACGCTGGTGCTCTCTACCGATCCTGCCCACTCCCTCGCCGACTCCCTCGATCAGCCTCTGGGGCACG
AGCCGCGGCGGGTGAGCGAGAACCTCTGGGCCGCCGAACTGGACGCCCTCGTGGAACTGGAAGAGAACTGGGGCTCGGTC
AAAAAATACATCACCACCGTCCTGCAGGCGCGCGGCCTCGATGGCATCCAGGCAGAAGAGTTGGCAGTGCTGCCGGGCAT
GGACGAGATCTTCTCCCTGGTGCGGGTCAAGCGACACTACGACGAGGCCGACTACGATGTGCTGATTATCGATTCGGCCC
CCACCGGCACGGCTTTGCGCCTATTGAGTCTGCCGGAGGTCTCAGGCTGGTACGTGCGCAAGTTCTTCAAGCCGATGCAG
GGAATCGCCAAGGCCCTCACGCCCATCTTCGACCCGGTGGCCCGGCGGGTGGTGGGCATCCCGCTGCCGAACGCCGAGGT
GATCGACGCGCCCTACGAGTTCTACGAAAAAATCGAGGCGTTGGAGCGCATTCTCACCGACAACACCCTCACCACCGTCC
GCCTAGTCACCAACCCCGAGAAGATGGTGATCAAAGAGTCGCTGCGCGCCCACGCCTATCTGAGCCTTTACAACGTGGCC
ACCGACCTGGTGATCGCCAACCGGATCATCCCCGACGGGGTCCAAGACCCGTACTTTCAGCGCTGGAAACAGGCCCAGCA
GGTTTACCGCCGGCAAATCCATGAAAACTTTGCCCCCCTGCCGGTGCGGGAGATCCCGCTCTACCAGGAGGAAATGGTGG
GTATCGCCGCTCTCGAACGCCTCAAAGACGATCTCTACGGTGAGGAGGATCCGGCGGCCGTGCTGTACGCCGAAACTACC
CTTAAGGTCGTTCAAGAGGCGGGTGCCTACCGCCTCGACCTCTATTTGCCCGGCGTGCCGAAGTCGGAGGTGCAACTGGC
CAAGACCGGCGATGAGTTGAACATTCGCATCGGCAACCACCGCCGCAACCTGGTGCTGCCGCAGTCGCTTGCTGCTCTGC
AGCCGAGTGGAGCCCGGATGCACGAGGACTTCCTACAGATTCGCTTCGTCGCTGCCGGTCCGTAG

Upstream 100 bases:

>100_bases
CGCCGATGGACCCGGAGGCTATTACCATTGAGATTAAGGAATCTTAAAAGTGAGCAACCCGATGGCGACGCAGAGCGCAG
CAGCAAGACGCCGGGACAAA

Downstream 100 bases:

>100_bases
ATAACGGCAGAATGCAAAAACCCGGCGAGAGCAGTACGTCGCCGGGCTTGATATGGCTTATCGCTTAGTAGCGGCGGTCG
CGGCCACCGCCGCCACCCGC

Product: anion transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRIILMTGKGGVGKTSMAAATGLRCAELGYRTLVLSTDPAHSLADSLDQPLGHEPRRVSENLWAAELDALVELEENWGSV
KKYITTVLQARGLDGIQAEELAVLPGMDEIFSLVRVKRHYDEADYDVLIIDSAPTGTALRLLSLPEVSGWYVRKFFKPMQ
GIAKALTPIFDPVARRVVGIPLPNAEVIDAPYEFYEKIEALERILTDNTLTTVRLVTNPEKMVIKESLRAHAYLSLYNVA
TDLVIANRIIPDGVQDPYFQRWKQAQQVYRRQIHENFAPLPVREIPLYQEEMVGIAALERLKDDLYGEEDPAAVLYAETT
LKVVQEAGAYRLDLYLPGVPKSEVQLAKTGDELNIRIGNHRRNLVLPQSLAALQPSGARMHEDFLQIRFVAAGP

Sequences:

>Translated_394_residues
MRIILMTGKGGVGKTSMAAATGLRCAELGYRTLVLSTDPAHSLADSLDQPLGHEPRRVSENLWAAELDALVELEENWGSV
KKYITTVLQARGLDGIQAEELAVLPGMDEIFSLVRVKRHYDEADYDVLIIDSAPTGTALRLLSLPEVSGWYVRKFFKPMQ
GIAKALTPIFDPVARRVVGIPLPNAEVIDAPYEFYEKIEALERILTDNTLTTVRLVTNPEKMVIKESLRAHAYLSLYNVA
TDLVIANRIIPDGVQDPYFQRWKQAQQVYRRQIHENFAPLPVREIPLYQEEMVGIAALERLKDDLYGEEDPAAVLYAETT
LKVVQEAGAYRLDLYLPGVPKSEVQLAKTGDELNIRIGNHRRNLVLPQSLAALQPSGARMHEDFLQIRFVAAGP
>Mature_394_residues
MRIILMTGKGGVGKTSMAAATGLRCAELGYRTLVLSTDPAHSLADSLDQPLGHEPRRVSENLWAAELDALVELEENWGSV
KKYITTVLQARGLDGIQAEELAVLPGMDEIFSLVRVKRHYDEADYDVLIIDSAPTGTALRLLSLPEVSGWYVRKFFKPMQ
GIAKALTPIFDPVARRVVGIPLPNAEVIDAPYEFYEKIEALERILTDNTLTTVRLVTNPEKMVIKESLRAHAYLSLYNVA
TDLVIANRIIPDGVQDPYFQRWKQAQQVYRRQIHENFAPLPVREIPLYQEEMVGIAALERLKDDLYGEEDPAAVLYAETT
LKVVQEAGAYRLDLYLPGVPKSEVQLAKTGDELNIRIGNHRRNLVLPQSLAALQPSGARMHEDFLQIRFVAAGP

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=270, Percent_Identity=24.8148148148148, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17557003, Length=293, Percent_Identity=26.2798634812287, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320103, Length=318, Percent_Identity=26.1006289308176, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586297, Length=312, Percent_Identity=23.7179487179487, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44009; Mature: 44009

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILMTGKGGVGKTSMAAATGLRCAELGYRTLVLSTDPAHSLADSLDQPLGHEPRRVSE
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHH
NLWAAELDALVELEENWGSVKKYITTVLQARGLDGIQAEELAVLPGMDEIFSLVRVKRHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHHHHHHHC
DEADYDVLIIDSAPTGTALRLLSLPEVSGWYVRKFFKPMQGIAKALTPIFDPVARRVVGI
CCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPNAEVIDAPYEFYEKIEALERILTDNTLTTVRLVTNPEKMVIKESLRAHAYLSLYNVA
CCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
TDLVIANRIIPDGVQDPYFQRWKQAQQVYRRQIHENFAPLPVREIPLYQEEMVGIAALER
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHH
LKDDLYGEEDPAAVLYAETTLKVVQEAGAYRLDLYLPGVPKSEVQLAKTGDELNIRIGNH
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHEEHEECCCEEEEEECCC
RRNLVLPQSLAALQPSGARMHEDFLQIRFVAAGP
CCCEECCHHHHHCCCCCCHHHHHHHEEEEEECCC
>Mature Secondary Structure
MRIILMTGKGGVGKTSMAAATGLRCAELGYRTLVLSTDPAHSLADSLDQPLGHEPRRVSE
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHH
NLWAAELDALVELEENWGSVKKYITTVLQARGLDGIQAEELAVLPGMDEIFSLVRVKRHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHHHHHHHC
DEADYDVLIIDSAPTGTALRLLSLPEVSGWYVRKFFKPMQGIAKALTPIFDPVARRVVGI
CCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPNAEVIDAPYEFYEKIEALERILTDNTLTTVRLVTNPEKMVIKESLRAHAYLSLYNVA
CCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
TDLVIANRIIPDGVQDPYFQRWKQAQQVYRRQIHENFAPLPVREIPLYQEEMVGIAALER
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHH
LKDDLYGEEDPAAVLYAETTLKVVQEAGAYRLDLYLPGVPKSEVQLAKTGDELNIRIGNH
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHEEHEECCCEEEEEECCC
RRNLVLPQSLAALQPSGARMHEDFLQIRFVAAGP
CCCEECCHHHHHCCCCCCHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]