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The map label for this gene is kefG [H]

Identifier: 37520911

GI number: 37520911

Start: 1434064

End: 1434699

Strand: Direct

Name: kefG [H]

Synonym: glr1342

Alternate gene names: 37520911

Gene position: 1434064-1434699 (Clockwise)

Preceding gene: 37520909

Following gene: 37520912

Centisome position: 30.78

GC content: 58.33

Gene sequence:

>636_bases
ATGGCCCGTACCCGTCGAGTGTTGATTCTATTTGCCCACCCGGCACTGGAAAAATCGCGGATGAATCGACAGCTCGTTCA
AGCCGTTCAAGGCATGGACTTCGTCACCATTCACGATCTGTACGAGGCGTATCCCAATTTCTACATCGACGTCAAACACG
AGCAGGAGTTGCTGCTCGCCCATGACATCATCGTCTTCCAGCATCCTTTTTACTGGTACAGCAGCCCGGCCATCCTCAAA
GAATGGCAGGACCTGGTGCTGGAGTACGGCTTTGCCTACGGGTATGAGGGCACGGCTTTGCGGGGCAAGAAGTTTTTAAG
TGCGATCACCACCGGCGGCGGCGAACAGGCCTATAGCCGTGAGGGGCACAACTACTTCACCATCCGCGAGTTGCTGGCTC
CTTTTGAGCAGACGGCCCGCCTGTGCGGCATGGAGTATCTGCCCCCATTCGTCATCCAGGGCACGCACCAGTTGCGCGAG
AAGCAGCAAATCGCCAATCACGTCGAGGACTACCGCAAGGCGATTGCAGCATTGCGCGACGATGCCGTCGACTGGGAGCG
CCTCCGGCAAAGCCGCCACTTCAACCACGACCTCGCCCAGCTGCTCCCGGCCCAGGAGATCGTCCACCGTGTCTAA

Upstream 100 bases:

>100_bases
TGTCGCGCTACGCTTGGGGGGCGTCCGGAGGCGGAATCGATCCCCATCGCAACCGCACGGCCGTACCCCAAAACCGGCCC
AAGCGTGGGAGGCAGTTCCA

Downstream 100 bases:

>100_bases
CGAAAACTTATTCTTTCAGGCGTTTATTTATCTGGCCGCCGCGGTGGTCTCGGTGCCGATCGCCAAGCGCCTCGGGCTCG
GCTCGGTGTTGGGCTATCTG

Product: NADP(H) oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MARTRRVLILFAHPALEKSRMNRQLVQAVQGMDFVTIHDLYEAYPNFYIDVKHEQELLLAHDIIVFQHPFYWYSSPAILK
EWQDLVLEYGFAYGYEGTALRGKKFLSAITTGGGEQAYSREGHNYFTIRELLAPFEQTARLCGMEYLPPFVIQGTHQLRE
KQQIANHVEDYRKAIAALRDDAVDWERLRQSRHFNHDLAQLLPAQEIVHRV

Sequences:

>Translated_211_residues
MARTRRVLILFAHPALEKSRMNRQLVQAVQGMDFVTIHDLYEAYPNFYIDVKHEQELLLAHDIIVFQHPFYWYSSPAILK
EWQDLVLEYGFAYGYEGTALRGKKFLSAITTGGGEQAYSREGHNYFTIRELLAPFEQTARLCGMEYLPPFVIQGTHQLRE
KQQIANHVEDYRKAIAALRDDAVDWERLRQSRHFNHDLAQLLPAQEIVHRV
>Mature_210_residues
ARTRRVLILFAHPALEKSRMNRQLVQAVQGMDFVTIHDLYEAYPNFYIDVKHEQELLLAHDIIVFQHPFYWYSSPAILKE
WQDLVLEYGFAYGYEGTALRGKKFLSAITTGGGEQAYSREGHNYFTIRELLAPFEQTARLCGMEYLPPFVIQGTHQLREK
QQIANHVEDYRKAIAALRDDAVDWERLRQSRHFNHDLAQLLPAQEIVHRV

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=146, Percent_Identity=35.6164383561644, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1789750, Length=176, Percent_Identity=43.75, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786231, Length=149, Percent_Identity=44.2953020134228, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 24703; Mature: 24572

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTRRVLILFAHPALEKSRMNRQLVQAVQGMDFVTIHDLYEAYPNFYIDVKHEQELLLA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHH
HDIIVFQHPFYWYSSPAILKEWQDLVLEYGFAYGYEGTALRGKKFLSAITTGGGEQAYSR
HHHHHEECCCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHC
EGHNYFTIRELLAPFEQTARLCGMEYLPPFVIQGTHQLREKQQIANHVEDYRKAIAALRD
CCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVDWERLRQSRHFNHDLAQLLPAQEIVHRV
CCCCHHHHHHHHCCCHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
ARTRRVLILFAHPALEKSRMNRQLVQAVQGMDFVTIHDLYEAYPNFYIDVKHEQELLLA
CCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHH
HDIIVFQHPFYWYSSPAILKEWQDLVLEYGFAYGYEGTALRGKKFLSAITTGGGEQAYSR
HHHHHEECCCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHC
EGHNYFTIRELLAPFEQTARLCGMEYLPPFVIQGTHQLREKQQIANHVEDYRKAIAALRD
CCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVDWERLRQSRHFNHDLAQLLPAQEIVHRV
CCCCHHHHHHHHCCCHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA