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The map label for this gene is rlmH

Identifier: 37520906

GI number: 37520906

Start: 1430009

End: 1430464

Strand: Reverse

Name: rlmH

Synonym: gll1337

Alternate gene names: 37520906

Gene position: 1430464-1430009 (Counterclockwise)

Preceding gene: 37520907

Following gene: 37520905

Centisome position: 30.7

GC content: 65.35

Gene sequence:

>456_bases
GTGAGGATCAAGCTGGTCGCGGTCGGACGGCTGCGCGAGGAGGCTTACGAGCGGGCCTGTGCAGAGTACGCCCGGCGGCT
GGCAGCCTATGCCCGCCTGGAATTGGTGGAAGTGCGCGACGCCCGCATCGCCGACAGCCGGGCGGGCCTGCTCAAAGAGG
GCCAGGCTCTGCTGGACCAGCTGCATCCCGGCGAGCACGCAGTCTTGCTCGACAGCGGCGGCAAGCAATTTACCAGCGTC
GAATTGGCCGATTGGCTCGAAAACCATACCGTGCAGGAGCCGGTCTTCATCGTCGGCTCAAGCCACGGCGTCGCTCCAAT
GGTTCGGGAGCGGGCACAGATGGTCTGGTCGCTCTCGAAGCTGACCTTTCCCCACGAACTGGCGCGGGTGATTGTGCTGG
AGCAGCTCTACCGCGCCGTCACCATCCTGGCCGGGCACCCTTACCACCATGGCTAA

Upstream 100 bases:

>100_bases
GGATCATCGGCATCGACGAGCGTGGGGCGTTGCGGGTATTGTTTTTAGACGGCGGTGAGGCGCTGGTCATGCCCAGCGAA
TTGCGGCTGGGCTACGCGCT

Downstream 100 bases:

>100_bases
GATAGATAGGCCGTTACCCCTGTCGCCATGCAAGCCCGCCGCATCGCCCGCGAACTCGCCTTGATGAGCATCGGTCAGAT
GCCCGCCGACCGTTCGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRIKLVAVGRLREEAYERACAEYARRLAAYARLELVEVRDARIADSRAGLLKEGQALLDQLHPGEHAVLLDSGGKQFTSV
ELADWLENHTVQEPVFIVGSSHGVAPMVRERAQMVWSLSKLTFPHELARVIVLEQLYRAVTILAGHPYHHG

Sequences:

>Translated_151_residues
MRIKLVAVGRLREEAYERACAEYARRLAAYARLELVEVRDARIADSRAGLLKEGQALLDQLHPGEHAVLLDSGGKQFTSV
ELADWLENHTVQEPVFIVGSSHGVAPMVRERAQMVWSLSKLTFPHELARVIVLEQLYRAVTILAGHPYHHG
>Mature_151_residues
MRIKLVAVGRLREEAYERACAEYARRLAAYARLELVEVRDARIADSRAGLLKEGQALLDQLHPGEHAVLLDSGGKQFTSV
ELADWLENHTVQEPVFIVGSSHGVAPMVRERAQMVWSLSKLTFPHELARVIVLEQLYRAVTILAGHPYHHG

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=154, Percent_Identity=35.7142857142857, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_GLOVI (Q7NKY9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924283.1
- ProteinModelPortal:   Q7NKY9
- SMR:   Q7NKY9
- GeneID:   2598799
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1337
- NMPDR:   fig|251221.1.peg.1337
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- BioCyc:   GVIO251221:GLL1337-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 16944; Mature: 16944

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKLVAVGRLREEAYERACAEYARRLAAYARLELVEVRDARIADSRAGLLKEGQALLDQ
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LHPGEHAVLLDSGGKQFTSVELADWLENHTVQEPVFIVGSSHGVAPMVRERAQMVWSLSK
CCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
LTFPHELARVIVLEQLYRAVTILAGHPYHHG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRIKLVAVGRLREEAYERACAEYARRLAAYARLELVEVRDARIADSRAGLLKEGQALLDQ
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LHPGEHAVLLDSGGKQFTSVELADWLENHTVQEPVFIVGSSHGVAPMVRERAQMVWSLSK
CCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
LTFPHELARVIVLEQLYRAVTILAGHPYHHG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292