Click here to switch to the map view.

The map label for this gene is aat

Identifier: 37520603

GI number: 37520603

Start: 1110711

End: 1111292

Strand: Direct

Name: aat

Synonym: glr1034

Alternate gene names: 37520603

Gene position: 1110711-1111292 (Clockwise)

Preceding gene: 37520588

Following gene: 37520608

Centisome position: 23.84

GC content: 59.97

Gene sequence:

>582_bases
ATGCTGGTAACTCTCACACCCGAACTGTTGCTGCAAGCGTATACCCAGGGCTTTTTCCCGATGGCCGAAGGCCAGGGTCA
ACGCATCTACTGGTACGAACCCGACCCGCGGGCCGTTTTTGAACTCGATAAAGTGCACTTCTCCAAGCGCCTGCTGCGGG
TGATCCGCCAGGAGCGCTTTGAGATTCGCTACAGCACCGCCTTTGAGCGGGTGATCCGCGCCTGTGCCGACCGACCTTCC
ACCTGGATCTCCGAGGAGATCATCCGCACCTACATTCGGCTTTACCGCACGGGCTACGGCCAGTCCGTCGAAAGCTGGCT
GGACGGCGAACTGGTAGGCGGGCTTTACGGCGTCAGCCTGGGCGGCGCCTTTTTCGGCGAGTCGATGTTTTGCCGGGTAA
GCGACGCTTCGAAAGTGGCGTTTTTTCATCTGGTCGAACGGCTTAGGGGGCGGGGTTTCGCACTGCTTGACACCCAGTTC
GCCAACGAGCATCTTGTGCAGTTCCACGTCGTCGAAATTCCGCGCCGGGAATACCGGCAGCGGCTCAAAGGAGCGCTCGC
CCTGCCGTGCAAATTTCGCTAA

Upstream 100 bases:

>100_bases
AAGCGCAACGAATTTAACTTACAGGCTGCAACCGTGGCGATAATAGATCCGCCGCCACACGCCCCCGTGCAGCCACAGAC
CTGGGCCGGGCGGATCTGTA

Downstream 100 bases:

>100_bases
CCGGCTACCACTCGACGATGTCGGTGAGGATAACGGTGTCGGGTTGATCGCCAAGCAGTGCCGACTCCTGGTTGCCGCGC
GGCACGCTCTGCAGCGGCGA

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MLVTLTPELLLQAYTQGFFPMAEGQGQRIYWYEPDPRAVFELDKVHFSKRLLRVIRQERFEIRYSTAFERVIRACADRPS
TWISEEIIRTYIRLYRTGYGQSVESWLDGELVGGLYGVSLGGAFFGESMFCRVSDASKVAFFHLVERLRGRGFALLDTQF
ANEHLVQFHVVEIPRREYRQRLKGALALPCKFR

Sequences:

>Translated_193_residues
MLVTLTPELLLQAYTQGFFPMAEGQGQRIYWYEPDPRAVFELDKVHFSKRLLRVIRQERFEIRYSTAFERVIRACADRPS
TWISEEIIRTYIRLYRTGYGQSVESWLDGELVGGLYGVSLGGAFFGESMFCRVSDASKVAFFHLVERLRGRGFALLDTQF
ANEHLVQFHVVEIPRREYRQRLKGALALPCKFR
>Mature_193_residues
MLVTLTPELLLQAYTQGFFPMAEGQGQRIYWYEPDPRAVFELDKVHFSKRLLRVIRQERFEIRYSTAFERVIRACADRPS
TWISEEIIRTYIRLYRTGYGQSVESWLDGELVGGLYGVSLGGAFFGESMFCRVSDASKVAFFHLVERLRGRGFALLDTQF
ANEHLVQFHVVEIPRREYRQRLKGALALPCKFR

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=181, Percent_Identity=40.8839779005525, Blast_Score=141, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_GLOVI (Q7NLT7)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923980.1
- ProteinModelPortal:   Q7NLT7
- SMR:   Q7NLT7
- GeneID:   2599152
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr1034
- NMPDR:   fig|251221.1.peg.1034
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- ProtClustDB:   PRK00301
- BioCyc:   GVIO251221:GLR1034-MONOMER
- BRENDA:   2.3.2.6
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 22527; Mature: 22527

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTLTPELLLQAYTQGFFPMAEGQGQRIYWYEPDPRAVFELDKVHFSKRLLRVIRQERF
CEEEECHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
EIRYSTAFERVIRACADRPSTWISEEIIRTYIRLYRTGYGQSVESWLDGELVGGLYGVSL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHH
GGAFFGESMFCRVSDASKVAFFHLVERLRGRGFALLDTQFANEHLVQFHVVEIPRREYRQ
CHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHEEEEEEECCHHHHHH
RLKGALALPCKFR
HHCCCCCCCCCCC
>Mature Secondary Structure
MLVTLTPELLLQAYTQGFFPMAEGQGQRIYWYEPDPRAVFELDKVHFSKRLLRVIRQERF
CEEEECHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
EIRYSTAFERVIRACADRPSTWISEEIIRTYIRLYRTGYGQSVESWLDGELVGGLYGVSL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHH
GGAFFGESMFCRVSDASKVAFFHLVERLRGRGFALLDTQFANEHLVQFHVVEIPRREYRQ
CHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHEEEEEEECCHHHHHH
RLKGALALPCKFR
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292