Click here to switch to the map view.

The map label for this gene is gidA

Identifier: 37520450

GI number: 37520450

Start: 931910

End: 933880

Strand: Reverse

Name: gidA

Synonym: gvip116

Alternate gene names: 37520450

Gene position: 933880-931910 (Counterclockwise)

Preceding gene: 37520455

Following gene: 37520449

Centisome position: 20.04

GC content: 64.89

Gene sequence:

>1971_bases
ATGTCTTGCTTGCCGGATTGGCTTGCGGCCGGCTGCCGCGACGGCGACGCAGCTTCGCATCCTACAATTAGATTACGATT
TCGAACTGCGACTGTGCATTATCTTGCTGAATTTGACGTCGTCGTCGTCGGCGCCGGCCACAGCGGCTGCGAAGCGGCCC
TCGCCGCCGCCCGCCTCGGCTGTCGAACACTCCTGGTCACCATGAACCTCGACACGATCGCTTGGCAACCGTGCAATCCG
GCGGTGGGCGGCCCGGCCAAGTCGCAGCTGGTCCACGAGGTCGATGCCCTAGGCGGCGAGATGGCCAAAATCACCGACCG
CACCTATCTGCAAAAGCGCGTCCTCAATAGTTCCCGCGGCCCGGCGGTCTGGGCGCTTCGGGCGCAGACCGACAAGCGCG
AGTATGCCCGCGAGCTGAAGCAGGTGCTCGAAGCCACCCCCAACCTCACCCTGCGCCAGGGACAGATTACCGACATCCAC
CTGGGTCCTCACGACGAAATTTGCGGGGTCGGCACGTTTTTTGACGTGCACTTTGCCTGCCGGGCGGTGATCTTGACCAC
CGGCACATTTTTGGGCGGGCGCATCTGGATTGGCCGCAAGTCGATGAGCGCCGGGCGGGCGGGCGAATTTGCCGCGGAGG
GTTTGACTGCGACCCTGGAGCGGTTGGGTTTTGAGACCGGGCGGCTCAAGACGGGCACCCCCGCCCGCGTCGACCGGCGC
ACGGTCGATTTTGGCGTCATGGAGGTGCAGCCGCCCGATCCCGAGTTGCGCTGGTTCTCGTTCGACCCGCGCGCCTGGGT
AGAGCGCGAGCAGCTCAACTGCTATCTCACGCGCACCACCGCCGCGACCCACCAAGTGATCCGCGACCATCTGCACCTCT
CGCCGATGTACAGTGGCGACATCGAGGCGCGCGGGCCGCGCTACTGCCCCAGCATCGAGGATAAGATCGTCCGCTTCGCC
GATAAAGAGAGCCACCAGATTTTTATCGAGCCGGAGGGCCGCGACACCCCCGAACTCTACGTCCAGGGCTTTTCGACCTC
GCTGCCGGAGACTGTCCAAATCGCGATGCTGCGCACCCTGCCGGGTCTGGAAGCGTGTGCCGTACTGCGGCCCGCCTACG
CGGTCGAGTACGACTACCTGCCTGCCACCCAGTGCTATGCGACCCTGATGACCAAGCGGGTGGAAGGACTGTTCTGCGCC
GGGCAGATCAACGGCACCACCGGTTACGAGGAGGCCGCCGCCCAGGGGATCGTGGCGGGGATCAACGCCGCGCGCCTGGT
GCGCGGCGAAGCGCTCGTGATCTTGCCCCGCGAAGGCTCCTACATCGGCACGCTTATCGACGATCTGGTCACCAAGGAGA
TCCGCGAGCCGTACCGGATGCTCACCAGCCGCTCGGAGTATCGCCTGGTGCTGCGCTCCGACAACGCCGATCGCCGCCTT
ACCCCGCTGGGCCGCGAGATCGGCCTGGTGGACGACGAGCGCTGGGGGTTGTACCAGAAAAAAATTGCCGCGATCACCTG
CGAGCGCCAACGCCTCGAGACCACACGCCTCAATGCCCGCGATCTGCCCGTCCACCTCGCCGCCAAACCGGGGTCGATCA
CCCTGGCGGACTTGCTGCGTCGGCCGGGGTTGCACTACGGCGATCTGGAGAGTCTGAATCAGGGGGTTCTCCTCGATGCG
CAGGTGCGCGAGGGCGTCGAAATCGAAGTGAAGTACAGCGGCTACATCGAGCGCCAGAACGAGCAAATTGAGCGGGTAAG
CGCCCAACACGCCCGGGTGATTCCCGCCGATCTCGACTACGAGCGGCTGAGCACCCTCTCCAAAGAATCCCGCGAGAAAT
TAAACCGCATACGCCCCCGGACCATCGGCCAGGCCGGCCGCATCGGTGGGGTGAACCCGGCGGATGTCAGTGCGCTCTTG
GTGTATCTAGAACTAGCCCAGGCTGGGCGTTTGACCCCTGCTGCCCCCTGA

Upstream 100 bases:

>100_bases
GAAGCTAAATCCGGTCCGGAGTGCCGATGTAGCGATGAGTTTGATCCATATACTTGGGTGTAAAGTCTGAAGGTGAATTC
GATGGCTATAAGGCATTCGT

Downstream 100 bases:

>100_bases
AAATGTGGAGAAAGACTACCGTGGGGTTTACAGACTATGCCGCTCGTCGTATACTTCAGGACTAGTGAGGGGTGAATGGA
AGAAGGGCTCAGGACGAAAC

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MSCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLGCRTLLVTMNLDTIAWQPCNP
AVGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRGPAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIH
LGPHDEICGVGTFFDVHFACRAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRR
TVDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGDIEARGPRYCPSIEDKIVRFA
DKESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTLPGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCA
GQINGTTGYEEAAAQGIVAGINAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRL
TPLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLRRPGLHYGDLESLNQGVLLDA
QVREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDYERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALL
VYLELAQAGRLTPAAP

Sequences:

>Translated_656_residues
MSCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLGCRTLLVTMNLDTIAWQPCNP
AVGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRGPAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIH
LGPHDEICGVGTFFDVHFACRAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRR
TVDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGDIEARGPRYCPSIEDKIVRFA
DKESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTLPGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCA
GQINGTTGYEEAAAQGIVAGINAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRL
TPLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLRRPGLHYGDLESLNQGVLLDA
QVREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDYERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALL
VYLELAQAGRLTPAAP
>Mature_655_residues
SCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLGCRTLLVTMNLDTIAWQPCNPA
VGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRGPAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIHL
GPHDEICGVGTFFDVHFACRAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRRT
VDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGDIEARGPRYCPSIEDKIVRFAD
KESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTLPGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCAG
QINGTTGYEEAAAQGIVAGINAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRLT
PLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLRRPGLHYGDLESLNQGVLLDAQ
VREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDYERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALLV
YLELAQAGRLTPAAP

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=644, Percent_Identity=41.7701863354037, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI19882217, Length=669, Percent_Identity=40.2092675635277, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI183227703, Length=684, Percent_Identity=39.327485380117, Blast_Score=404, Evalue=1e-112,
Organism=Escherichia coli, GI2367273, Length=621, Percent_Identity=49.4363929146538, Blast_Score=570, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17534255, Length=621, Percent_Identity=39.6135265700483, Blast_Score=431, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321202, Length=658, Percent_Identity=42.8571428571429, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI24658174, Length=641, Percent_Identity=42.7457098283931, Blast_Score=428, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_GLOVI (Q7NM86)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923827.1
- HSSP:   Q5SH33
- ProteinModelPortal:   Q7NM86
- SMR:   Q7NM86
- GeneID:   2599307
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.881
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   GVIO251221:GLL0881-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 72593; Mature: 72462

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLG
CCCCCCHHHCCCCCCCCCCCCEEEEEEEEEEEEEEEECCEEEEECCCCCHHHHHHHHHHC
CRTLLVTMNLDTIAWQPCNPAVGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRG
CEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIHLGPHDEICGVGTFFDVHFAC
CEEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHH
RAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRR
HHHHEECCCEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
TVDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGD
EEEEEEEEECCCCCCCEEEECCCHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
IEARGPRYCPSIEDKIVRFADKESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTL
CCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHEEECCCCCCCHHHHHHHHHHC
PGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCAGQINGTTGYEEAAAQGIVAG
CCHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHC
INAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRL
CCHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TPLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLR
CCCCCCCCCCCCCCCCHHHHHHHHEEHHHHHHHHHCCCCCCCCEEEECCCCCEEHHHHHH
RPGLHYGDLESLNQGVLLDAQVREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDY
CCCCCCCCHHHCCCCEEEEHHHCCCCEEEEEECCEEECCHHHHHHHHHHHCEECCCCCCH
ERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALLVYLELAQAGRLTPAAP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLG
CCCCCHHHCCCCCCCCCCCCEEEEEEEEEEEEEEEECCEEEEECCCCCHHHHHHHHHHC
CRTLLVTMNLDTIAWQPCNPAVGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRG
CEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIHLGPHDEICGVGTFFDVHFAC
CEEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHH
RAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRR
HHHHEECCCEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
TVDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGD
EEEEEEEEECCCCCCCEEEECCCHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
IEARGPRYCPSIEDKIVRFADKESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTL
CCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHEEECCCCCCCHHHHHHHHHHC
PGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCAGQINGTTGYEEAAAQGIVAG
CCHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHC
INAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRL
CCHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TPLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLR
CCCCCCCCCCCCCCCCHHHHHHHHEEHHHHHHHHHCCCCCCCCEEEECCCCCEEHHHHHH
RPGLHYGDLESLNQGVLLDAQVREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDY
CCCCCCCCHHHCCCCEEEEHHHCCCCEEEEEECCEEECCHHHHHHHHHHHCEECCCCCCH
ERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALLVYLELAQAGRLTPAAP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292