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The map label for this gene is ctaD [H]

Identifier: 37520309

GI number: 37520309

Start: 791625

End: 793289

Strand: Direct

Name: ctaD [H]

Synonym: gvip078

Alternate gene names: 37520309

Gene position: 791625-793289 (Clockwise)

Preceding gene: 37520308

Following gene: 37520311

Centisome position: 16.99

GC content: 60.18

Gene sequence:

>1665_bases
ATGGTCGATGTTTCTGCTTCCCAGACCGCTTCCAACCGGGCGACCGGCGATTGGCGGCGCTATTTCACCTTCAACACCGA
CCACAAGGTGATCGGCATCCAGTATCTGGTCACCGCCTTTACCTTCTACCTGATAGGCGGGTTGCAGGCGATGATTATCC
GGGCGGAACTGGCTACACCTGAGTCGAACGTCGTCAGCCAGGACGCCTACAACGGCCTGTTCACCCTGCACGCCACGATC
ATGATTTTTTTGTGGATCATCCCGATGTCGGCCGGGCTCGGCAACTACTTGGTGCCACTGATGATCGGCGCACGGGATAT
GGCTTTTCCGCGGTTGAATGCTGCGAGCTTCTGGCTCATTCCCCCGGCGGGACTGGTGCTGCTCTCGTGCTATCTGGTCC
CGAGCGGCCCGCCCCAGGCAGGTTGGTGGTCCTATCCGCCCCTGAGCCTGCAGGCGATTCAGGTGGGTGAGCAGACGTTC
TTCAACTACGGCCAGTCGCTGTGGTGTATCGGCGTCGGCATCCTTGGGATCTCCTCGATTTTGGCGGCGGTCAACTTTAT
CGCCACGATCCTGGCGATGCGCACCGAGGGAATGACCCTCTTCCGCATGCCGATCTTTATCTGGAATACCCTGGTCACTT
CGGTGATCACGCTGTTGGGAGTACCGGTGCTCACCGCCGCCGTGGTGCTGCTGTGGTCGGATTTGGCTTTGGGGACCGCC
TTTTTTGACCCGGCCAGAGGCGGCGACCCGGTGGTCTACCAGCACATGTTCTGGTTCTACTCGCACCCGGCCGTCTACAT
CATGATCCTGCCCGCGATGGGCGCGGTCTCGGAGATCCTGCCCACCTTCGCACGCAAGCCGCTGTTCGGTTACCGGGTGG
TGGCCATCTCGACGGTGGCCATCGGGGTGATCGGCTTTACGGTCTGGGCGCACCACATGTTCACCTCCGGCACCCCCGAC
TGGTTGCGGCTGTTTTTTATGATCACCTCGATGACGATCGCCGTACCGACCGGGATCAAAGTCTTTAACTGGGTAGCCAC
CATCTGGGGAGGCAAACTCTGGCTCACCACGCCGATGCTCTTTGCCATGGGTTTCGTGGGTATGTTCGTGGCGGGGGGGG
TGACCGGGGTGATGCTCGCCTCCGTGCCGGTGGATATCCACGTAAGCAACACCTACTTCGTGGTCGCCCATCTGCACTAC
GTGCTGTTCGGAGGCAGCGTGCTCGGTCTGTACGCCGCGGTATACTACTGGTTTCCGAAGATGACCGGACGGTTTCTCAA
CGAAACCCTGGGCAAAGTCCACTTCTGGACCACGATCATCGGCCTGAACCTTGCCTTTCTGCCGATGCACCAGGTGGGAC
TGTTGGGCATGCCGCGTCGGGTGGCGGAATATCTGCCGCAGTTCACTCTCCTCAATCAAATCGTTTCGCTCGGGGCGGCG
GTGCTGGGTATCTCGACACTGCCGTTTCTGCTCAATGTGCTCATCAGTTGGCTTGCCGGCACTAAGGCAGAGAATGACCC
CTGGCGCTCCCACGGTCTAGAGTGGACCATCTCCTCGCCGCCGCCGCTCGAAAATTTTGGTCAGCTGCCCGTGATCACCG
CCGGGCCTTACGAATACGGCATCATCGGCAAAGGTGCTGGCCCGGAGGATCCTTCAGAGACCTAG

Upstream 100 bases:

>100_bases
CCGTCGTTGACCCTGTGCCTTTGCTGACGCCTGTGCGCTCGCCCCAGACGGCCCGGCTTCTCGAACACCTCCAGCAACCC
AACAGAGGATCGTAATAGTC

Downstream 100 bases:

>100_bases
CTGTTAGCCGGGCATGGAAGAAGCGCATCGTTTTACTTGGCACTAAACGGCTGCTTAAGCACTTTCAAGCCGCTCGCTCA
ACACAGGTTCGTGCATGGCC

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MVDVSASQTASNRATGDWRRYFTFNTDHKVIGIQYLVTAFTFYLIGGLQAMIIRAELATPESNVVSQDAYNGLFTLHATI
MIFLWIIPMSAGLGNYLVPLMIGARDMAFPRLNAASFWLIPPAGLVLLSCYLVPSGPPQAGWWSYPPLSLQAIQVGEQTF
FNYGQSLWCIGVGILGISSILAAVNFIATILAMRTEGMTLFRMPIFIWNTLVTSVITLLGVPVLTAAVVLLWSDLALGTA
FFDPARGGDPVVYQHMFWFYSHPAVYIMILPAMGAVSEILPTFARKPLFGYRVVAISTVAIGVIGFTVWAHHMFTSGTPD
WLRLFFMITSMTIAVPTGIKVFNWVATIWGGKLWLTTPMLFAMGFVGMFVAGGVTGVMLASVPVDIHVSNTYFVVAHLHY
VLFGGSVLGLYAAVYYWFPKMTGRFLNETLGKVHFWTTIIGLNLAFLPMHQVGLLGMPRRVAEYLPQFTLLNQIVSLGAA
VLGISTLPFLLNVLISWLAGTKAENDPWRSHGLEWTISSPPPLENFGQLPVITAGPYEYGIIGKGAGPEDPSET

Sequences:

>Translated_554_residues
MVDVSASQTASNRATGDWRRYFTFNTDHKVIGIQYLVTAFTFYLIGGLQAMIIRAELATPESNVVSQDAYNGLFTLHATI
MIFLWIIPMSAGLGNYLVPLMIGARDMAFPRLNAASFWLIPPAGLVLLSCYLVPSGPPQAGWWSYPPLSLQAIQVGEQTF
FNYGQSLWCIGVGILGISSILAAVNFIATILAMRTEGMTLFRMPIFIWNTLVTSVITLLGVPVLTAAVVLLWSDLALGTA
FFDPARGGDPVVYQHMFWFYSHPAVYIMILPAMGAVSEILPTFARKPLFGYRVVAISTVAIGVIGFTVWAHHMFTSGTPD
WLRLFFMITSMTIAVPTGIKVFNWVATIWGGKLWLTTPMLFAMGFVGMFVAGGVTGVMLASVPVDIHVSNTYFVVAHLHY
VLFGGSVLGLYAAVYYWFPKMTGRFLNETLGKVHFWTTIIGLNLAFLPMHQVGLLGMPRRVAEYLPQFTLLNQIVSLGAA
VLGISTLPFLLNVLISWLAGTKAENDPWRSHGLEWTISSPPPLENFGQLPVITAGPYEYGIIGKGAGPEDPSET
>Mature_554_residues
MVDVSASQTASNRATGDWRRYFTFNTDHKVIGIQYLVTAFTFYLIGGLQAMIIRAELATPESNVVSQDAYNGLFTLHATI
MIFLWIIPMSAGLGNYLVPLMIGARDMAFPRLNAASFWLIPPAGLVLLSCYLVPSGPPQAGWWSYPPLSLQAIQVGEQTF
FNYGQSLWCIGVGILGISSILAAVNFIATILAMRTEGMTLFRMPIFIWNTLVTSVITLLGVPVLTAAVVLLWSDLALGTA
FFDPARGGDPVVYQHMFWFYSHPAVYIMILPAMGAVSEILPTFARKPLFGYRVVAISTVAIGVIGFTVWAHHMFTSGTPD
WLRLFFMITSMTIAVPTGIKVFNWVATIWGGKLWLTTPMLFAMGFVGMFVAGGVTGVMLASVPVDIHVSNTYFVVAHLHY
VLFGGSVLGLYAAVYYWFPKMTGRFLNETLGKVHFWTTIIGLNLAFLPMHQVGLLGMPRRVAEYLPQFTLLNQIVSLGAA
VLGISTLPFLLNVLISWLAGTKAENDPWRSHGLEWTISSPPPLENFGQLPVITAGPYEYGIIGKGAGPEDPSET

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=512, Percent_Identity=42.3828125, Blast_Score=361, Evalue=1e-100,
Organism=Escherichia coli, GI1786634, Length=543, Percent_Identity=39.4106813996317, Blast_Score=377, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=38.8679245283019, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.6153846153846, Blast_Score=245, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=37.7510040160643, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60704; Mature: 60704

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVSASQTASNRATGDWRRYFTFNTDHKVIGIQYLVTAFTFYLIGGLQAMIIRAELATP
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESNVVSQDAYNGLFTLHATIMIFLWIIPMSAGLGNYLVPLMIGARDMAFPRLNAASFWLI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHCCCCCCCCCEEEE
PPAGLVLLSCYLVPSGPPQAGWWSYPPLSLQAIQVGEQTFFNYGQSLWCIGVGILGISSI
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LAAVNFIATILAMRTEGMTLFRMPIFIWNTLVTSVITLLGVPVLTAAVVLLWSDLALGTA
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFDPARGGDPVVYQHMFWFYSHPAVYIMILPAMGAVSEILPTFARKPLFGYRVVAISTVA
HCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IGVIGFTVWAHHMFTSGTPDWLRLFFMITSMTIAVPTGIKVFNWVATIWGGKLWLTTPML
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHH
FAMGFVGMFVAGGVTGVMLASVPVDIHVSNTYFVVAHLHYVLFGGSVLGLYAAVYYWFPK
HHHHHHHHHHHCCHHHHHHEECCEEEEECCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGRFLNETLGKVHFWTTIIGLNLAFLPMHQVGLLGMPRRVAEYLPQFTLLNQIVSLGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHH
VLGISTLPFLLNVLISWLAGTKAENDPWRSHGLEWTISSPPPLENFGQLPVITAGPYEYG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCHHHCCCCCEEEECCCCCC
IIGKGAGPEDPSET
EEECCCCCCCCCCC
>Mature Secondary Structure
MVDVSASQTASNRATGDWRRYFTFNTDHKVIGIQYLVTAFTFYLIGGLQAMIIRAELATP
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESNVVSQDAYNGLFTLHATIMIFLWIIPMSAGLGNYLVPLMIGARDMAFPRLNAASFWLI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHCCCCCCCCCEEEE
PPAGLVLLSCYLVPSGPPQAGWWSYPPLSLQAIQVGEQTFFNYGQSLWCIGVGILGISSI
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LAAVNFIATILAMRTEGMTLFRMPIFIWNTLVTSVITLLGVPVLTAAVVLLWSDLALGTA
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFDPARGGDPVVYQHMFWFYSHPAVYIMILPAMGAVSEILPTFARKPLFGYRVVAISTVA
HCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IGVIGFTVWAHHMFTSGTPDWLRLFFMITSMTIAVPTGIKVFNWVATIWGGKLWLTTPML
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHH
FAMGFVGMFVAGGVTGVMLASVPVDIHVSNTYFVVAHLHYVLFGGSVLGLYAAVYYWFPK
HHHHHHHHHHHCCHHHHHHEECCEEEEECCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGRFLNETLGKVHFWTTIIGLNLAFLPMHQVGLLGMPRRVAEYLPQFTLLNQIVSLGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHH
VLGISTLPFLLNVLISWLAGTKAENDPWRSHGLEWTISSPPPLENFGQLPVITAGPYEYG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCHHHCCCCCEEEECCCCCC
IIGKGAGPEDPSET
EEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]