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The map label for this gene is argD [H]

Identifier: 37520116

GI number: 37520116

Start: 581851

End: 583065

Strand: Direct

Name: argD [H]

Synonym: gvip059

Alternate gene names: 37520116

Gene position: 581851-583065 (Clockwise)

Preceding gene: 37520112

Following gene: 37520117

Centisome position: 12.49

GC content: 65.27

Gene sequence:

>1215_bases
GTGGTAGCCGTGATGACAGTCCAGCAAGCTTTTGAACAGCATGTGATGCACACTTACGCGCGCTTCTCTGTGGTCTTCGA
ACGCGGCGAAGGGTGCTACCTCGAGGACAGCGAAGGCCGACGCTACCTGGATTTTGTAGCCGGCATCGCCACCTGCGTCC
TCGGACACGCCCATCCGGTCCTGAGCGCGGCCGTCGCCGAGCAGGCCCGCACGCTCATCCACGTCTCCAACCTGTATTAC
ACGCCCCAGCAGGCCTGTCTGGCCGAATGGCTCACCGCCCATTCGGCAGCCGACCAAGTGTTCTTCTGCAACTCGGGGGC
CGAAGCCAACGAGGGTGCCATCAAGCTTGCGCGCAAGTACGGCCGCACGGTGCTGGGCATCGCCGAGCCACAAATCATCT
GCGCCCACCAGAGCTTCCACGGCCGCACGATGGCCACCGTCACCGCCACCGGTCAACCCAAATACCAAAAGCATTTCCAT
CCGCTGGTGCCGGGTTTCGTGCACGTCCCCTACAACGACTTTGAGGCGCTGCGCGCCCAGGTCACCGATGCGACGGCCGC
TGTGCTCATCGAACCGATTCAGGGCGAGGGCGGCGTGGTGCCGGGGGATGTCGAATTTTTCCAGAAGCTGCGGCGCTTCT
GCTCCGAGCGGCGCATTCTGTTGATGCTCGACGAAGTGCAGACCGGCATGGGCCGCACCGGTCGCCTGTTCGGCTACGAG
CACCTGGGCATTGAACCCGACGTGTTTACCCTGGCCAAGGCCCTGGGCGGCGGCGTGCCCATCGGTGCGCTGTGCGCCAA
AGAAGCCTTTGCGATTTTCGAGCCGGGGGATCACGCGAGCACTTTCGGGGGCAATCCCCTCGCCTGCGCCGCGGCCCTTG
CCGTCTGCCAGACACTCGAAGCGGAGCAACTGGTGGACAACGCCCGCGAGCGCGGAGCCCAGCTTGCCGCCGGTCTTGGT
CGGCTGGTAGAGCGCTTCAAGCCGCTGGTGCGCACGGCGCGCGGCCGTGGCCTGATGCAGGGGCTGGTGCTCTCTGAGCC
GCGCGCCGCCGAAATCGTGCGTCTGGCCATGGAGCAAGGGCTGTTATTGGTCTCCGCCGGGCCTGAGGTGATCCGCTTCG
TGCCGCCGCTGATCGTGAGCGCCATCGAAGTAGACGAAGCTCTCGCCATCTTGGAGGGCGTCTTTGCCCGCCTGCCGGTG
ACGGTCACCGCTTAG

Upstream 100 bases:

>100_bases
GGGCTGCTGTATACCTCATCCGACAGGAACTGACGGCGAAGATGCCGTTCAGCAACGAGGCGCGTTCGGGAAGGATGGAG
TAGAGTGGTTTTGGTTTGAA

Downstream 100 bases:

>100_bases
ACGCCGGGCTCCAAGTACACTATGCGCTGAGGTGCCGTCATGCAATCTCTGGTGCTCTCTCCCCATCCGGCGCTTGCTCC
CTTTGTGACCGGCTACTGGT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MVAVMTVQQAFEQHVMHTYARFSVVFERGEGCYLEDSEGRRYLDFVAGIATCVLGHAHPVLSAAVAEQARTLIHVSNLYY
TPQQACLAEWLTAHSAADQVFFCNSGAEANEGAIKLARKYGRTVLGIAEPQIICAHQSFHGRTMATVTATGQPKYQKHFH
PLVPGFVHVPYNDFEALRAQVTDATAAVLIEPIQGEGGVVPGDVEFFQKLRRFCSERRILLMLDEVQTGMGRTGRLFGYE
HLGIEPDVFTLAKALGGGVPIGALCAKEAFAIFEPGDHASTFGGNPLACAAALAVCQTLEAEQLVDNARERGAQLAAGLG
RLVERFKPLVRTARGRGLMQGLVLSEPRAAEIVRLAMEQGLLLVSAGPEVIRFVPPLIVSAIEVDEALAILEGVFARLPV
TVTA

Sequences:

>Translated_404_residues
MVAVMTVQQAFEQHVMHTYARFSVVFERGEGCYLEDSEGRRYLDFVAGIATCVLGHAHPVLSAAVAEQARTLIHVSNLYY
TPQQACLAEWLTAHSAADQVFFCNSGAEANEGAIKLARKYGRTVLGIAEPQIICAHQSFHGRTMATVTATGQPKYQKHFH
PLVPGFVHVPYNDFEALRAQVTDATAAVLIEPIQGEGGVVPGDVEFFQKLRRFCSERRILLMLDEVQTGMGRTGRLFGYE
HLGIEPDVFTLAKALGGGVPIGALCAKEAFAIFEPGDHASTFGGNPLACAAALAVCQTLEAEQLVDNARERGAQLAAGLG
RLVERFKPLVRTARGRGLMQGLVLSEPRAAEIVRLAMEQGLLLVSAGPEVIRFVPPLIVSAIEVDEALAILEGVFARLPV
TVTA
>Mature_404_residues
MVAVMTVQQAFEQHVMHTYARFSVVFERGEGCYLEDSEGRRYLDFVAGIATCVLGHAHPVLSAAVAEQARTLIHVSNLYY
TPQQACLAEWLTAHSAADQVFFCNSGAEANEGAIKLARKYGRTVLGIAEPQIICAHQSFHGRTMATVTATGQPKYQKHFH
PLVPGFVHVPYNDFEALRAQVTDATAAVLIEPIQGEGGVVPGDVEFFQKLRRFCSERRILLMLDEVQTGMGRTGRLFGYE
HLGIEPDVFTLAKALGGGVPIGALCAKEAFAIFEPGDHASTFGGNPLACAAALAVCQTLEAEQLVDNARERGAQLAAGLG
RLVERFKPLVRTARGRGLMQGLVLSEPRAAEIVRLAMEQGLLLVSAGPEVIRFVPPLIVSAIEVDEALAILEGVFARLPV
TVTA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=36.71875, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=38.047138047138, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI13994255, Length=449, Percent_Identity=27.1714922048998, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=27.4698795180723, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI188536080, Length=436, Percent_Identity=25.4587155963303, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38679950, Length=436, Percent_Identity=25.4587155963303, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38679946, Length=436, Percent_Identity=25.4587155963303, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI37574042, Length=432, Percent_Identity=27.3148148148148, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=26.9141531322506, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI226442709, Length=406, Percent_Identity=27.0935960591133, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1788044, Length=386, Percent_Identity=43.2642487046632, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=40.8376963350785, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI145693181, Length=396, Percent_Identity=36.6161616161616, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=35.3233830845771, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=34.8258706467662, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=416, Percent_Identity=30.0480769230769, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=31.8471337579618, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=396, Percent_Identity=37.6262626262626, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI25144274, Length=394, Percent_Identity=31.7258883248731, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=32.1917808219178, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=26.3888888888889, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71981843, Length=179, Percent_Identity=36.3128491620112, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=451, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=36.4089775561097, Blast_Score=260, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.7394540942928, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6321456, Length=372, Percent_Identity=27.4193548387097, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=345, Percent_Identity=23.4782608695652, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=36.2204724409449, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=32.3185011709602, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=31.4420803782506, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356575, Length=406, Percent_Identity=29.5566502463054, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281366494, Length=439, Percent_Identity=25.9681093394077, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667139, Length=439, Percent_Identity=25.9681093394077, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667143, Length=439, Percent_Identity=25.9681093394077, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43590; Mature: 43590

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVMTVQQAFEQHVMHTYARFSVVFERGEGCYLEDSEGRRYLDFVAGIATCVLGHAHPV
CEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHH
LSAAVAEQARTLIHVSNLYYTPQQACLAEWLTAHSAADQVFFCNSGAEANEGAIKLARKY
HHHHHHHHHHHHEEHHHCEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
GRTVLGIAEPQIICAHQSFHGRTMATVTATGQPKYQKHFHPLVPGFVHVPYNDFEALRAQ
CCEEEEECCCCEEEECCCCCCCEEEEEEECCCCCHHHCCCCCCCCEEECCCCHHHHHHHH
VTDATAAVLIEPIQGEGGVVPGDVEFFQKLRRFCSERRILLMLDEVQTGMGRTGRLFGYE
HHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEECCH
HLGIEPDVFTLAKALGGGVPIGALCAKEAFAIFEPGDHASTFGGNPLACAAALAVCQTLE
HCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
AEQLVDNARERGAQLAAGLGRLVERFKPLVRTARGRGLMQGLVLSEPRAAEIVRLAMEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCC
LLLVSAGPEVIRFVPPLIVSAIEVDEALAILEGVFARLPVTVTA
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure
MVAVMTVQQAFEQHVMHTYARFSVVFERGEGCYLEDSEGRRYLDFVAGIATCVLGHAHPV
CEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHH
LSAAVAEQARTLIHVSNLYYTPQQACLAEWLTAHSAADQVFFCNSGAEANEGAIKLARKY
HHHHHHHHHHHHEEHHHCEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
GRTVLGIAEPQIICAHQSFHGRTMATVTATGQPKYQKHFHPLVPGFVHVPYNDFEALRAQ
CCEEEEECCCCEEEECCCCCCCEEEEEEECCCCCHHHCCCCCCCCEEECCCCHHHHHHHH
VTDATAAVLIEPIQGEGGVVPGDVEFFQKLRRFCSERRILLMLDEVQTGMGRTGRLFGYE
HHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEECCH
HLGIEPDVFTLAKALGGGVPIGALCAKEAFAIFEPGDHASTFGGNPLACAAALAVCQTLE
HCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
AEQLVDNARERGAQLAAGLGRLVERFKPLVRTARGRGLMQGLVLSEPRAAEIVRLAMEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCC
LLLVSAGPEVIRFVPPLIVSAIEVDEALAILEGVFARLPVTVTA
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]