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The map label for this gene is yggV [C]

Identifier: 37520101

GI number: 37520101

Start: 569381

End: 569968

Strand: Direct

Name: yggV [C]

Synonym: glr0532

Alternate gene names: 37520101

Gene position: 569381-569968 (Clockwise)

Preceding gene: 37520099

Following gene: 37520102

Centisome position: 12.22

GC content: 65.14

Gene sequence:

>588_bases
ATGATGCGTTTCCTAATATTGGCAACAAACAATCAAGGAAAGCTACAGGAACTGCGCCGTTTACTCGCTGGCACGGGCTG
GGTGGTGCAGGCGGCCCCGCCGGATTTTGCGGTGGAGGAAACCGGGACGACCTTTGCTGAGAACGCTCGCCTCAAGGCCC
TCGCGGCGGCGGAGCGCACGGGGGAGTGGAGTGTGGGGGACGATTCGGGTTTGGCGGTCGACGCCCTCGGCGGAGCGCCG
GGAGTGTATTCGGCGCGCTACGGCCGCAACGACGGTGAGCGCATCTCCCGCCTGCTCGCTGCGCTGGCGGGGCAAGCCGA
CCGGGGTGCGCGCTTCATCTGCGCCATCGCCCTGGCCGAACCCGGCCGGGTACTGAAAGAGGTCGAAGCCGAATGCCGGG
GCGTCATCCTGCACGCCCCGCGCGGCAACGGCGGCTTTGGCTACGACCCGATTTTTCTGGTGCCCGAACTGGACAAAACC
TTTGCCGAACTCGACATCGTCGAGAAAGAGCGCCACAGCCACCGGGGCCGGGCAGTGCGCAAGTTGCTCTCGGGGTGCAG
CCGAGGTACGTTCATTGTTGACCATTAG

Upstream 100 bases:

>100_bases
CCACATCTTGATATCGCTCATTGTTTCATTGAGCTTCGTTGCAATCCCCTTGAGACAATAATACAAAGATGTCAGTGTTT
ACTTTTTGTTCGTTGAACTA

Downstream 100 bases:

>100_bases
CGGGCGGATCGTCGATGGGCACAGCGCCCTCGACCAGGCCCCGATCACCGGTGAATCGATGCCGGTGGAAAAGGCGGTGG
GGGAGGAAGTGTACGCCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MMRFLILATNNQGKLQELRRLLAGTGWVVQAAPPDFAVEETGTTFAENARLKALAAAERTGEWSVGDDSGLAVDALGGAP
GVYSARYGRNDGERISRLLAALAGQADRGARFICAIALAEPGRVLKEVEAECRGVILHAPRGNGGFGYDPIFLVPELDKT
FAELDIVEKERHSHRGRAVRKLLSGCSRGTFIVDH

Sequences:

>Translated_195_residues
MMRFLILATNNQGKLQELRRLLAGTGWVVQAAPPDFAVEETGTTFAENARLKALAAAERTGEWSVGDDSGLAVDALGGAP
GVYSARYGRNDGERISRLLAALAGQADRGARFICAIALAEPGRVLKEVEAECRGVILHAPRGNGGFGYDPIFLVPELDKT
FAELDIVEKERHSHRGRAVRKLLSGCSRGTFIVDH
>Mature_195_residues
MMRFLILATNNQGKLQELRRLLAGTGWVVQAAPPDFAVEETGTTFAENARLKALAAAERTGEWSVGDDSGLAVDALGGAP
GVYSARYGRNDGERISRLLAALAGQADRGARFICAIALAEPGRVLKEVEAECRGVILHAPRGNGGFGYDPIFLVPELDKT
FAELDIVEKERHSHRGRAVRKLLSGCSRGTFIVDH

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=200, Percent_Identity=45, Blast_Score=134, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17556833, Length=182, Percent_Identity=29.6703296703297, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_GLOVI (Q7NN81)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923478.1
- ProteinModelPortal:   Q7NN81
- SMR:   Q7NN81
- GeneID:   2599639
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr0532
- NMPDR:   fig|251221.1.peg.532
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- BioCyc:   GVIO251221:GLR0532-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20985; Mature: 20985

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRFLILATNNQGKLQELRRLLAGTGWVVQAAPPDFAVEETGTTFAENARLKALAAAERT
CEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHCCHHHHHHHHHCC
GEWSVGDDSGLAVDALGGAPGVYSARYGRNDGERISRLLAALAGQADRGARFICAIALAE
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
PGRVLKEVEAECRGVILHAPRGNGGFGYDPIFLVPELDKTFAELDIVEKERHSHRGRAVR
CHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
KLLSGCSRGTFIVDH
HHHHCCCCCCEEECC
>Mature Secondary Structure
MMRFLILATNNQGKLQELRRLLAGTGWVVQAAPPDFAVEETGTTFAENARLKALAAAERT
CEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHCCHHHHHHHHHCC
GEWSVGDDSGLAVDALGGAPGVYSARYGRNDGERISRLLAALAGQADRGARFICAIALAE
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
PGRVLKEVEAECRGVILHAPRGNGGFGYDPIFLVPELDKTFAELDIVEKERHSHRGRAVR
CHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
KLLSGCSRGTFIVDH
HHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292