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The map label for this gene is gap1 [H]

Identifier: 37520099

GI number: 37520099

Start: 567754

End: 568770

Strand: Direct

Name: gap1 [H]

Synonym: gvip056

Alternate gene names: 37520099

Gene position: 567754-568770 (Clockwise)

Preceding gene: 37520092

Following gene: 37520101

Centisome position: 12.19

GC content: 59.59

Gene sequence:

>1017_bases
ATGACGATTAAAGTAGCAATCAACGGCTTCGGGAGGATCGGGCGCAACTTCTTGCGCTGCTGGTTGGGTCGCAAACAGTC
GGATTTTGAAGTCGTTGCCATCAACGACACCTCCGACCCCAACACCAATGCACACCTGCTTAAGTACGATTCGATGCTGG
GCCAGTTCAGCGGCGAGGTGAGCGCCGACGAAAATTCGCTCACCGCCAACGGTCACACCATCAAGTGCTTTTCCGACCGC
AATCCGCTCAATCTACCCTGGAAGGATTGGGGTGTCGATCTGGTGATCGAATCGACGGGTGTATTCACCAGCCGCGACGG
TGCCTCCAAGCACCTTGCCGCCGGCGCCAAAAAAGTGCTCATCACCGCGCCGGGCAAGAATGACGACGGCACCTTCGTCA
TGGGTGTCAACGATCACAACTACGACCCTGAGAAGCACACGATTATCTCCAATGCTTCTTGCACCACCAACTGCCTGGCC
CCGGTGGCCAAGGTGCTCCACGAGAACTTCAAGATCGTCAAGGGCACGATGACCACCATCCACAGCTACACCGGCGACCA
GCGCCTGCTCGATGCGAGCCACCGCGACTGGCGCCGCGCCCGCGCTGCTGCCCTCAGCATCGTGCCCACCAGCACCGGGG
CGGCCAAGGCCATCGGCCTGGTGCTGCCCGAACTGAAGGGCAAGCTGGATGGTCTGGCCTTCCGGGTGCCCACCCCCAAC
GTCTCGGTGGTGGACCTGGTGGTCGAAGTCGAAAAACCCACCCTTGTCGAGCAGGTCAACCACGTCCTCAAAGAGGCCTC
CGAGAACGAACTCAAAGGCATCCTCGCCTTTAGCGAAATTCCGCTAGTGTCGATCGACTACCGGATTACCGACGTCTCGT
CGATCGTGGACGCCCAGCTCACCATGGTGCTCAAGGACAACCTGGTAAAGGTGATCTCCTGGTACGACAACGAGTGGGGC
TACTCCCAGCGCGTCGTCGATTTGGCCGAACTGGTCGCCCGCAAGTGGGCAGCTTAA

Upstream 100 bases:

>100_bases
TCAGAGAACCGGCAAGCCCCCTGGTAGAATTTTCAATGTAAACTTCAGATGGCTGGGGCTTACCCCACACCATGGGTGTT
CATTCAGCAGGGACGCAATA

Downstream 100 bases:

>100_bases
GTAACGCCTCAGCCCACACAAAAAAAGCGGGTGCTCCAGCACCCGCTTTTTGCTTCAGGAGACTTGGGCTTCTTGTTGCG
GCTCGAACTCCGGACACAGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTIKVAINGFGRIGRNFLRCWLGRKQSDFEVVAINDTSDPNTNAHLLKYDSMLGQFSGEVSADENSLTANGHTIKCFSDR
NPLNLPWKDWGVDLVIESTGVFTSRDGASKHLAAGAKKVLITAPGKNDDGTFVMGVNDHNYDPEKHTIISNASCTTNCLA
PVAKVLHENFKIVKGTMTTIHSYTGDQRLLDASHRDWRRARAAALSIVPTSTGAAKAIGLVLPELKGKLDGLAFRVPTPN
VSVVDLVVEVEKPTLVEQVNHVLKEASENELKGILAFSEIPLVSIDYRITDVSSIVDAQLTMVLKDNLVKVISWYDNEWG
YSQRVVDLAELVARKWAA

Sequences:

>Translated_338_residues
MTIKVAINGFGRIGRNFLRCWLGRKQSDFEVVAINDTSDPNTNAHLLKYDSMLGQFSGEVSADENSLTANGHTIKCFSDR
NPLNLPWKDWGVDLVIESTGVFTSRDGASKHLAAGAKKVLITAPGKNDDGTFVMGVNDHNYDPEKHTIISNASCTTNCLA
PVAKVLHENFKIVKGTMTTIHSYTGDQRLLDASHRDWRRARAAALSIVPTSTGAAKAIGLVLPELKGKLDGLAFRVPTPN
VSVVDLVVEVEKPTLVEQVNHVLKEASENELKGILAFSEIPLVSIDYRITDVSSIVDAQLTMVLKDNLVKVISWYDNEWG
YSQRVVDLAELVARKWAA
>Mature_337_residues
TIKVAINGFGRIGRNFLRCWLGRKQSDFEVVAINDTSDPNTNAHLLKYDSMLGQFSGEVSADENSLTANGHTIKCFSDRN
PLNLPWKDWGVDLVIESTGVFTSRDGASKHLAAGAKKVLITAPGKNDDGTFVMGVNDHNYDPEKHTIISNASCTTNCLAP
VAKVLHENFKIVKGTMTTIHSYTGDQRLLDASHRDWRRARAAALSIVPTSTGAAKAIGLVLPELKGKLDGLAFRVPTPNV
SVVDLVVEVEKPTLVEQVNHVLKEASENELKGILAFSEIPLVSIDYRITDVSSIVDAQLTMVLKDNLVKVISWYDNEWGY
SQRVVDLAELVARKWAA

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=51.3432835820895, Blast_Score=325, Evalue=3e-89,
Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=49.390243902439, Blast_Score=322, Evalue=3e-88,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=51.3432835820895, Blast_Score=350, Evalue=9e-98,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=45.2887537993921, Blast_Score=296, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=48.8165680473373, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=48.8165680473373, Blast_Score=314, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=48.5207100591716, Blast_Score=308, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=48.5207100591716, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=52.6946107784431, Blast_Score=340, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=52.0958083832335, Blast_Score=334, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=52.0958083832335, Blast_Score=332, Evalue=4e-92,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=50.2994011976048, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=50.2994011976048, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=49.8498498498498, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=49.7005988023952, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=49.7005988023952, Blast_Score=317, Evalue=9e-87,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37055; Mature: 36923

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVAINGFGRIGRNFLRCWLGRKQSDFEVVAINDTSDPNTNAHLLKYDSMLGQFSGEV
CEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHCCCCC
SADENSLTANGHTIKCFSDRNPLNLPWKDWGVDLVIESTGVFTSRDGASKHLAAGAKKVL
CCCCCCEECCCCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCHHHHCCCCEEE
ITAPGKNDDGTFVMGVNDHNYDPEKHTIISNASCTTNCLAPVAKVLHENFKIVKGTMTTI
EECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHH
HSYTGDQRLLDASHRDWRRARAAALSIVPTSTGAAKAIGLVLPELKGKLDGLAFRVPTPN
HHCCCCCHHHCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
VSVVDLVVEVEKPTLVEQVNHVLKEASENELKGILAFSEIPLVSIDYRITDVSSIVDAQL
CEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHEEEEECCCCEEEEEEEEECHHHHHHHHH
TMVLKDNLVKVISWYDNEWGYSQRVVDLAELVARKWAA
HHHHHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVAINGFGRIGRNFLRCWLGRKQSDFEVVAINDTSDPNTNAHLLKYDSMLGQFSGEV
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHCCCCC
SADENSLTANGHTIKCFSDRNPLNLPWKDWGVDLVIESTGVFTSRDGASKHLAAGAKKVL
CCCCCCEECCCCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCHHHHCCCCEEE
ITAPGKNDDGTFVMGVNDHNYDPEKHTIISNASCTTNCLAPVAKVLHENFKIVKGTMTTI
EECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHH
HSYTGDQRLLDASHRDWRRARAAALSIVPTSTGAAKAIGLVLPELKGKLDGLAFRVPTPN
HHCCCCCHHHCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
VSVVDLVVEVEKPTLVEQVNHVLKEASENELKGILAFSEIPLVSIDYRITDVSSIVDAQL
CEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHEEEEECCCCEEEEEEEEECHHHHHHHHH
TMVLKDNLVKVISWYDNEWGYSQRVVDLAELVARKWAA
HHHHHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]