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The map label for this gene is sbcD [H]

Identifier: 37520082

GI number: 37520082

Start: 550839

End: 552197

Strand: Direct

Name: sbcD [H]

Synonym: glr0513

Alternate gene names: 37520082

Gene position: 550839-552197 (Clockwise)

Preceding gene: 37520076

Following gene: 37520083

Centisome position: 11.82

GC content: 65.12

Gene sequence:

>1359_bases
ATGGTTCGTCTGCTGCACATTTCGGACATCCACCTGGGTAGCGGCCTATCCCACGGGCGCATCAACCCCGCCACCGGGTT
GCATACCCGTTTTGAAGATTTTTTGTATTGTCTGTCGCAGGCAATCGACCGCGGCCTCGCCGAGGGGGTTGACCTGGCGC
TGTTCGGGGGAGACGCATTTCCGAACGCCACCCCGGAGCCGACCCACCAGGAGGAGTTTGCCCGCCAGTTCAAGCGCCTC
ACCGACGCCGGCATTCCGACGGTGCTGCTGGTGGGCAACCACGACCTGCACGGGCGGGGGGTTGGGGGGGCGAGCCTCAA
TATTTATGCGGCGCTGCAGGTGCCGGGCTTTGTGGTGGGCTCCCGGCTGCAGATTCATCCGATCGCCACGCGCTCGGGGC
CGGTGCAGGTGTTGAGCTTGCCCTGGGTGAACCGCTCGACGCTGCTGACGCGCGAGGAGATGCGCGGCAAGAGCCTCGAG
CAGGTTGATCTCGCCCTGGTCGAGCGGATGAAATTGGCCCTCGAAGCGCAGGTGCGCCGCCTCGACCCGGCGGTACCGAC
GGTCTTGCTCGGCCATCTGATGGTCGAAAACGCCGTCTTTGGGGCCGAGCGCCACCTGGCGGTGGGCCGCAGCTTCAGCA
TTCCGCTTGCGATGCTCGCCCGTTCCGAGTTCGACTACGTGGCCCTTGGCCACGTCCATCGCCATCAGGTGCTCTGCGAA
GATCCGCCCATCATCTACCCGGGATCGATCGAGCGGGTCGATTTTGGCGAAGAAAAAGAATCCAAAGGCTTTATCCTCGC
TGAGGTCGAGCGCGGCCGCTGCCGCTACGAATTTGTGAGCGTGCCCGCCCGCAGCTTCAAGACGATCCAGGCCAACCTCG
CCGACAGCGGCGATCCGCAGGGCGACCTGGCGGCGATCTTACGCAAGCACAAAATCGAAGGGGCGATCGTGCGGGTGCTC
TACCGTTTGCATCCCCACCAGATCGAGCGCATCGACACCGCCAGCTTGCGCCAGATGCTGGAGGGGGCGTTTTCTTACCA
GTTGCAGCCGGAGCTGATTAGCCAGCTCAGCCAGCCGCGGGTGCCGGGGCTGGGCGAAAGTTGCGCCCTCGATCCGATCG
ACGCCCTCAGACAGTACCTCGAGAGCCGCCCCGAACTGGCCGATTTGCGCCTGGCCCTCGTCGAAGCGGCCGAGGCGCTG
ATCAAGGGCGACAGCCCCGGTCTGGCCGACACCGACGAGTGCGAGAGCGACGCCGAGGTGCTGGAGGTGACCACTACCGC
CGCCCTCGATCTTCTCGCGCGCGAGGAGGGTCTACCCGCCGGCGGCACCAACGGCCAACTCGGTCTATTTCACGCTTGA

Upstream 100 bases:

>100_bases
TAACGAAATGGTATCTGATTGTGCAGTTTTTTTAAGGGCTTTCTGTCGTCTGGCGGCCACAGGCTGTACAATGCGTTGAG
GACATGCGTCTATAGGGCTT

Downstream 100 bases:

>100_bases
TAGATATCGGTATGGACCGGTTGATCCGGGTGCGTGTAGCTGTACTCACCGCGGCCACACAGTCAGCCGGTGTATCTTAA
GGAGGATCAATTCTCCCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MVRLLHISDIHLGSGLSHGRINPATGLHTRFEDFLYCLSQAIDRGLAEGVDLALFGGDAFPNATPEPTHQEEFARQFKRL
TDAGIPTVLLVGNHDLHGRGVGGASLNIYAALQVPGFVVGSRLQIHPIATRSGPVQVLSLPWVNRSTLLTREEMRGKSLE
QVDLALVERMKLALEAQVRRLDPAVPTVLLGHLMVENAVFGAERHLAVGRSFSIPLAMLARSEFDYVALGHVHRHQVLCE
DPPIIYPGSIERVDFGEEKESKGFILAEVERGRCRYEFVSVPARSFKTIQANLADSGDPQGDLAAILRKHKIEGAIVRVL
YRLHPHQIERIDTASLRQMLEGAFSYQLQPELISQLSQPRVPGLGESCALDPIDALRQYLESRPELADLRLALVEAAEAL
IKGDSPGLADTDECESDAEVLEVTTTAALDLLAREEGLPAGGTNGQLGLFHA

Sequences:

>Translated_452_residues
MVRLLHISDIHLGSGLSHGRINPATGLHTRFEDFLYCLSQAIDRGLAEGVDLALFGGDAFPNATPEPTHQEEFARQFKRL
TDAGIPTVLLVGNHDLHGRGVGGASLNIYAALQVPGFVVGSRLQIHPIATRSGPVQVLSLPWVNRSTLLTREEMRGKSLE
QVDLALVERMKLALEAQVRRLDPAVPTVLLGHLMVENAVFGAERHLAVGRSFSIPLAMLARSEFDYVALGHVHRHQVLCE
DPPIIYPGSIERVDFGEEKESKGFILAEVERGRCRYEFVSVPARSFKTIQANLADSGDPQGDLAAILRKHKIEGAIVRVL
YRLHPHQIERIDTASLRQMLEGAFSYQLQPELISQLSQPRVPGLGESCALDPIDALRQYLESRPELADLRLALVEAAEAL
IKGDSPGLADTDECESDAEVLEVTTTAALDLLAREEGLPAGGTNGQLGLFHA
>Mature_452_residues
MVRLLHISDIHLGSGLSHGRINPATGLHTRFEDFLYCLSQAIDRGLAEGVDLALFGGDAFPNATPEPTHQEEFARQFKRL
TDAGIPTVLLVGNHDLHGRGVGGASLNIYAALQVPGFVVGSRLQIHPIATRSGPVQVLSLPWVNRSTLLTREEMRGKSLE
QVDLALVERMKLALEAQVRRLDPAVPTVLLGHLMVENAVFGAERHLAVGRSFSIPLAMLARSEFDYVALGHVHRHQVLCE
DPPIIYPGSIERVDFGEEKESKGFILAEVERGRCRYEFVSVPARSFKTIQANLADSGDPQGDLAAILRKHKIEGAIVRVL
YRLHPHQIERIDTASLRQMLEGAFSYQLQPELISQLSQPRVPGLGESCALDPIDALRQYLESRPELADLRLALVEAAEAL
IKGDSPGLADTDECESDAEVLEVTTTAALDLLAREEGLPAGGTNGQLGLFHA

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 49346; Mature: 49346

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRLLHISDIHLGSGLSHGRINPATGLHTRFEDFLYCLSQAIDRGLAEGVDLALFGGDAF
CEEEEEECCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PNATPEPTHQEEFARQFKRLTDAGIPTVLLVGNHDLHGRGVGGASLNIYAALQVPGFVVG
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCEEEC
SRLQIHPIATRSGPVQVLSLPWVNRSTLLTREEMRGKSLEQVDLALVERMKLALEAQVRR
CEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LDPAVPTVLLGHLMVENAVFGAERHLAVGRSFSIPLAMLARSEFDYVALGHVHRHQVLCE
CCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCCCCEEEECCHHHCCEEEC
DPPIIYPGSIERVDFGEEKESKGFILAEVERGRCRYEFVSVPARSFKTIQANLADSGDPQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHEEECCCCCCCC
GDLAAILRKHKIEGAIVRVLYRLHPHQIERIDTASLRQMLEGAFSYQLQPELISQLSQPR
HHHHHHHHHHCCHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHCCCC
VPGLGESCALDPIDALRQYLESRPELADLRLALVEAAEALIKGDSPGLADTDECESDAEV
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LEVTTTAALDLLAREEGLPAGGTNGQLGLFHA
EEHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MVRLLHISDIHLGSGLSHGRINPATGLHTRFEDFLYCLSQAIDRGLAEGVDLALFGGDAF
CEEEEEECCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PNATPEPTHQEEFARQFKRLTDAGIPTVLLVGNHDLHGRGVGGASLNIYAALQVPGFVVG
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCEEEC
SRLQIHPIATRSGPVQVLSLPWVNRSTLLTREEMRGKSLEQVDLALVERMKLALEAQVRR
CEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LDPAVPTVLLGHLMVENAVFGAERHLAVGRSFSIPLAMLARSEFDYVALGHVHRHQVLCE
CCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCCCCEEEECCHHHCCEEEC
DPPIIYPGSIERVDFGEEKESKGFILAEVERGRCRYEFVSVPARSFKTIQANLADSGDPQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHEEECCCCCCCC
GDLAAILRKHKIEGAIVRVLYRLHPHQIERIDTASLRQMLEGAFSYQLQPELISQLSQPR
HHHHHHHHHHCCHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHCCCC
VPGLGESCALDPIDALRQYLESRPELADLRLALVEAAEALIKGDSPGLADTDECESDAEV
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LEVTTTAALDLLAREEGLPAGGTNGQLGLFHA
EEHHHHHHHHHHHHHCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA