Click here to switch to the map view.

The map label for this gene is ytfL [C]

Identifier: 37519950

GI number: 37519950

Start: 398341

End: 399660

Strand: Direct

Name: ytfL [C]

Synonym: glr0381

Alternate gene names: 37519950

Gene position: 398341-399660 (Clockwise)

Preceding gene: 37519945

Following gene: 37519951

Centisome position: 8.55

GC content: 64.62

Gene sequence:

>1320_bases
ATGCCCTCGGTAATCTTTGAGATTTTGATTGTCCTGGTGCTGGTCGTCGCCAACGGTGTGTTTGCGATGTCCGAGATGGC
GGTGGTCTCCTCGCGCAAGGCGCGTCTGCAGCAGATGGCCGGCGAGGGCAACACCGGTGCGCGGGTGGCTGTGGAGTTGG
CCGACGCGCCCAACCGTTTTCTCTCGACGGTGCAGATCGGGATCACGTTGATTGGTATTTTTGCCGGCGCCTACGGCGGG
GCGACGATTGCAGGCACCCTGGCGCCACAGCTTGCGCGGGTAAGCTGGCTCGCTGCCTACAGCGAGGCGCTGGCCTTCGT
CCTGGTGGTCGGCACCATCACCTATCTGTCGCTGGTTCTGGGGGAATTGTTGCCCAAGCGCCTGGCCCTGAGTAACCCCG
AGCGCATTGCCGCGCGCATCGCCGTTCCGATGAGTGTGCTCTCGCGCGTCGCCGCTCCACTGGTCAAACTGTTGAGCCTC
TCGACCGATCTGGCCCTCAAGGCGCTCGGAGTCAAACCCTCTGCGGCGCTTGCCGTCACCGAGGAGGAAATCCGCCTGCT
CATCGAGCAAGGCACCGAGACCGGCGCCATCGCCCACAGCGAACAGGATCTGCTCGAGCGCGTCTTCAGCTTCGGCGACC
GGCAGGTGGCGGCGCTGATGACGCCGCGCCCGGACATCGTCTGGCTCGATCTCAAAGATTCCGAAGCGGAAAACCGGCGC
AAACTCGCGGCGTTTCACCACTCGCAGTTCCCGGTGTGCCTGGGAGAACTCGACAAATTCCTGGGGGTGGTCCGGGTAAA
GGATCTGTTCGAGCGCTTGCTCGCCGCTCGGCCGCTCACTCTGGAGGAAGCTTTGCTCCAGCCGCTGGTGGTACCGGAGA
CGGCACCCGCCCTGGTGGTGCTGGAGCAGTTCAAAAAGTCGGGGATCCACATGGCGCTGGTGGTCGATGAATTCGGGGGT
GTCCAGGGTCTGGTCACCCTCACGGACATCCTCGAAGCTCTGGTGGGAGATTTGCCTGTGGACGGCACGACCGATGAGGC
GCAGGCGGTGCGGCGCGAGGACGGCTCGTGGCTGGTGGACGGGTCGTTGAGCCTCGACGAACTGGAGCACCTGGTCGAAC
CGTTGCCCGAGCTGCCGCGCGTCGGCTATCGGACCGTCGGGGGCCTGGTCATGGCCCAACTGGGCCGTATCCCGAAAGCA
ACCGACCACTTCAATCTGGGGCCGTGCCGCTTCGAAGTCGTCGACATGGACGGCAACCGCGTCGACCGGGTGCTCATCAC
CACCTTGGGGGCCGGGGCCGAACGAGATTCGCCGCCTTGA

Upstream 100 bases:

>100_bases
AAACTGGTCGATGGGAGTATGCCTGTGACGAAGATAGCAGCGTATCGTATATTTTGCTCCGGAAGCCATTTCGGGGCATG
CTCTATTCAAAATTACAACT

Downstream 100 bases:

>100_bases
GGGAACGCGCTTCAAGGCAGCTGAAGCAGGACCAATAGGGGGAAGCATGACGTCGGTATTGAAGCCTGAAGAGGAACAAG
CTCAGAAGAAGCCTGGGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPSVIFEILIVLVLVVANGVFAMSEMAVVSSRKARLQQMAGEGNTGARVAVELADAPNRFLSTVQIGITLIGIFAGAYGG
ATIAGTLAPQLARVSWLAAYSEALAFVLVVGTITYLSLVLGELLPKRLALSNPERIAARIAVPMSVLSRVAAPLVKLLSL
STDLALKALGVKPSAALAVTEEEIRLLIEQGTETGAIAHSEQDLLERVFSFGDRQVAALMTPRPDIVWLDLKDSEAENRR
KLAAFHHSQFPVCLGELDKFLGVVRVKDLFERLLAARPLTLEEALLQPLVVPETAPALVVLEQFKKSGIHMALVVDEFGG
VQGLVTLTDILEALVGDLPVDGTTDEAQAVRREDGSWLVDGSLSLDELEHLVEPLPELPRVGYRTVGGLVMAQLGRIPKA
TDHFNLGPCRFEVVDMDGNRVDRVLITTLGAGAERDSPP

Sequences:

>Translated_439_residues
MPSVIFEILIVLVLVVANGVFAMSEMAVVSSRKARLQQMAGEGNTGARVAVELADAPNRFLSTVQIGITLIGIFAGAYGG
ATIAGTLAPQLARVSWLAAYSEALAFVLVVGTITYLSLVLGELLPKRLALSNPERIAARIAVPMSVLSRVAAPLVKLLSL
STDLALKALGVKPSAALAVTEEEIRLLIEQGTETGAIAHSEQDLLERVFSFGDRQVAALMTPRPDIVWLDLKDSEAENRR
KLAAFHHSQFPVCLGELDKFLGVVRVKDLFERLLAARPLTLEEALLQPLVVPETAPALVVLEQFKKSGIHMALVVDEFGG
VQGLVTLTDILEALVGDLPVDGTTDEAQAVRREDGSWLVDGSLSLDELEHLVEPLPELPRVGYRTVGGLVMAQLGRIPKA
TDHFNLGPCRFEVVDMDGNRVDRVLITTLGAGAERDSPP
>Mature_438_residues
PSVIFEILIVLVLVVANGVFAMSEMAVVSSRKARLQQMAGEGNTGARVAVELADAPNRFLSTVQIGITLIGIFAGAYGGA
TIAGTLAPQLARVSWLAAYSEALAFVLVVGTITYLSLVLGELLPKRLALSNPERIAARIAVPMSVLSRVAAPLVKLLSLS
TDLALKALGVKPSAALAVTEEEIRLLIEQGTETGAIAHSEQDLLERVFSFGDRQVAALMTPRPDIVWLDLKDSEAENRRK
LAAFHHSQFPVCLGELDKFLGVVRVKDLFERLLAARPLTLEEALLQPLVVPETAPALVVLEQFKKSGIHMALVVDEFGGV
QGLVTLTDILEALVGDLPVDGTTDEAQAVRREDGSWLVDGSLSLDELEHLVEPLPELPRVGYRTVGGLVMAQLGRIPKAT
DHFNLGPCRFEVVDMDGNRVDRVLITTLGAGAERDSPP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=352, Percent_Identity=28.9772727272727, Blast_Score=183, Evalue=3e-46,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=33.6405529953917, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI145693175, Length=411, Percent_Identity=28.9537712895377, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI87082033, Length=312, Percent_Identity=33.974358974359, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=34.1880341880342, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786879, Length=244, Percent_Identity=29.0983606557377, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47074; Mature: 46943

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVIFEILIVLVLVVANGVFAMSEMAVVSSRKARLQQMAGEGNTGARVAVELADAPNRF
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
LSTVQIGITLIGIFAGAYGGATIAGTLAPQLARVSWLAAYSEALAFVLVVGTITYLSLVL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELLPKRLALSNPERIAARIAVPMSVLSRVAAPLVKLLSLSTDLALKALGVKPSAALAVT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEE
EEEIRLLIEQGTETGAIAHSEQDLLERVFSFGDRQVAALMTPRPDIVWLDLKDSEAENRR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCHHHH
KLAAFHHSQFPVCLGELDKFLGVVRVKDLFERLLAARPLTLEEALLQPLVVPETAPALVV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
LEQFKKSGIHMALVVDEFGGVQGLVTLTDILEALVGDLPVDGTTDEAQAVRREDGSWLVD
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEE
GSLSLDELEHLVEPLPELPRVGYRTVGGLVMAQLGRIPKATDHFNLGPCRFEVVDMDGNR
CCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCC
VDRVLITTLGAGAERDSPP
CHHHEEEECCCCCCCCCCC
>Mature Secondary Structure 
PSVIFEILIVLVLVVANGVFAMSEMAVVSSRKARLQQMAGEGNTGARVAVELADAPNRF
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
LSTVQIGITLIGIFAGAYGGATIAGTLAPQLARVSWLAAYSEALAFVLVVGTITYLSLVL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELLPKRLALSNPERIAARIAVPMSVLSRVAAPLVKLLSLSTDLALKALGVKPSAALAVT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEE
EEEIRLLIEQGTETGAIAHSEQDLLERVFSFGDRQVAALMTPRPDIVWLDLKDSEAENRR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCHHHH
KLAAFHHSQFPVCLGELDKFLGVVRVKDLFERLLAARPLTLEEALLQPLVVPETAPALVV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
LEQFKKSGIHMALVVDEFGGVQGLVTLTDILEALVGDLPVDGTTDEAQAVRREDGSWLVD
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEE
GSLSLDELEHLVEPLPELPRVGYRTVGGLVMAQLGRIPKATDHFNLGPCRFEVVDMDGNR
CCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCC
VDRVLITTLGAGAERDSPP
CHHHEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]