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The map label for this gene is pdxJ

Identifier: 37519672

GI number: 37519672

Start: 102938

End: 103657

Strand: Reverse

Name: pdxJ

Synonym: gvip010

Alternate gene names: 37519672

Gene position: 103657-102938 (Counterclockwise)

Preceding gene: 37519675

Following gene: 37519671

Centisome position: 2.22

GC content: 64.44

Gene sequence:

>720_bases
GTGCCTACCCTCGGGGTCAACATCGATCACGTCGCTACGATCCGTCAGGCGCGCCGCACCGTCGAGCCTGATCCGGCGGC
GGCGGCGGTACTGGTGGAACTGGCGGGTGCTGACGGAATTACCGTCCATCTGCGCGAAGATCGCCGCCATATTCAAGATC
GCGATGTCGAGATTCTGCGGCGCACGGTACGCACACACCTCAACCTGGAGATGGCCGCCACCCGGGCGATGGTGGACTTT
GCTCTGGACGTGCGGCCGGACTACGTGACGCTGGTACCCGAACGGCGCGAGGAGGTGACCACCGAGGGCGGCCTCGATGT
GGGCGGTCAGATTGCATCGGTGGGTCTGGCGGTCGAGCAGTTGCAATGCGCAGGCATTCCGGTGAGTTTGTTCGTCGATC
CGGATGCCGCTCAACTGCAAGCTTCGGCCCGCACCGGAGCCAAGTTTGTCGAACTGCACACCGGACGCTACGCCGAGGCC
AGGGGCGAGCAGGCCCAGCGCAGCGAACTGGCGCAGCTTGCCGCCGCCTGCGATGAAGCCCAGGCTCTGGGTCTGCGGGT
CAATGCCGGTCATGGCCTGACGTACTGGAATGTCGCACCGGTGGCGCGCTTGTCGGGTATGGAAGAACTCAATATCGGAC
ACTCGATTATTGCCCGGGCGGTGCTGGTGGGTCTCGAGCGGGCGGTGCGCGAAATGAAGCAGGCGATGATAGCTGGATGA

Upstream 100 bases:

>100_bases
GGTACACCGCGCCGATGAGAATAACTACTTAGGCACAAATGCCTGGTGCGGGTTTGCCCAGGTCGAGCGATAAACTGGAG
CAGTTGTCCAGGAGAACAGC

Downstream 100 bases:

>100_bases
AGACTGTTCGCCTGCGGGCCGCCGCCAAGATCAATCTCTACCTCGAGATACTCGGGGTACGCCCCGACAACTTCCACGAA
TTGGTGATGGTGCTGCAGAG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPTLGVNIDHVATIRQARRTVEPDPAAAAVLVELAGADGITVHLREDRRHIQDRDVEILRRTVRTHLNLEMAATRAMVDF
ALDVRPDYVTLVPERREEVTTEGGLDVGGQIASVGLAVEQLQCAGIPVSLFVDPDAAQLQASARTGAKFVELHTGRYAEA
RGEQAQRSELAQLAAACDEAQALGLRVNAGHGLTYWNVAPVARLSGMEELNIGHSIIARAVLVGLERAVREMKQAMIAG

Sequences:

>Translated_239_residues
MPTLGVNIDHVATIRQARRTVEPDPAAAAVLVELAGADGITVHLREDRRHIQDRDVEILRRTVRTHLNLEMAATRAMVDF
ALDVRPDYVTLVPERREEVTTEGGLDVGGQIASVGLAVEQLQCAGIPVSLFVDPDAAQLQASARTGAKFVELHTGRYAEA
RGEQAQRSELAQLAAACDEAQALGLRVNAGHGLTYWNVAPVARLSGMEELNIGHSIIARAVLVGLERAVREMKQAMIAG
>Mature_238_residues
PTLGVNIDHVATIRQARRTVEPDPAAAAVLVELAGADGITVHLREDRRHIQDRDVEILRRTVRTHLNLEMAATRAMVDFA
LDVRPDYVTLVPERREEVTTEGGLDVGGQIASVGLAVEQLQCAGIPVSLFVDPDAAQLQASARTGAKFVELHTGRYAEAR
GEQAQRSELAQLAAACDEAQALGLRVNAGHGLTYWNVAPVARLSGMEELNIGHSIIARAVLVGLERAVREMKQAMIAG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=234, Percent_Identity=58.5470085470086, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_GLOVI (Q7NPF2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923049.1
- ProteinModelPortal:   Q7NPF2
- SMR:   Q7NPF2
- GeneID:   2600080
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.103
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   GVIO251221:GLL0103-MONOMER
- BRENDA:   2.6.99.2
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 25762; Mature: 25631

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 191-191 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLGVNIDHVATIRQARRTVEPDPAAAAVLVELAGADGITVHLREDRRHIQDRDVEILR
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCHHHHH
RTVRTHLNLEMAATRAMVDFALDVRPDYVTLVPERREEVTTEGGLDVGGQIASVGLAVEQ
HHHHHHCCHHHHHHHHHHHHHEECCCCEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHH
LQCAGIPVSLFVDPDAAQLQASARTGAKFVELHTGRYAEARGEQAQRSELAQLAAACDEA
HHHCCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHH
QALGLRVNAGHGLTYWNVAPVARLSGMEELNIGHSIIARAVLVGLERAVREMKQAMIAG
HHCEEEEECCCCEEEECCCHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTLGVNIDHVATIRQARRTVEPDPAAAAVLVELAGADGITVHLREDRRHIQDRDVEILR
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCHHHHH
RTVRTHLNLEMAATRAMVDFALDVRPDYVTLVPERREEVTTEGGLDVGGQIASVGLAVEQ
HHHHHHCCHHHHHHHHHHHHHEECCCCEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHH
LQCAGIPVSLFVDPDAAQLQASARTGAKFVELHTGRYAEARGEQAQRSELAQLAAACDEA
HHHCCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHH
QALGLRVNAGHGLTYWNVAPVARLSGMEELNIGHSIIARAVLVGLERAVREMKQAMIAG
HHCEEEEECCCCEEEECCCHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292