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The map label for this gene is mrdB [H]

Identifier: 34499816

GI number: 34499816

Start: 4702323

End: 4703354

Strand: Direct

Name: mrdB [H]

Synonym: CV_4361

Alternate gene names: 34499816

Gene position: 4702323-4703354 (Clockwise)

Preceding gene: 34499815

Following gene: 34499817

Centisome position: 98.97

GC content: 64.44

Gene sequence:

>1032_bases
ATGCTGTTCCTCGGCCTGATCTTCGCGGTCAGCATGGTGCTGCTGTACTCCGCCAACAACCAGTCCTTCGACAAGATAGA
CAACAAGCTGATCTACACCGCGATGGCGCTGACCGTGATGTGGGTGATCGCGCGGATGCGGCCGCAGAGCGTGATGAACT
TCGCGCCGCCCATCTACGTCATCGGCGTGCTGCTGCTGATCGCGGTGCATTTCAAGGGCATCACCGTCAACGGCTCCACC
CGCTGGCTGAGCCTGGGCGTCACCCGCATCCAGCCGTCGGAGATCCTGAAGATCGCGCTGCCGATGATGCTGGCCTGGTT
CTTCCAGAAGTACGAGCTGTCGCTGCGCTGGTGGCACTACCTGATCGCCGCCGCCATCATGCTGGTGCCGGTGGGCCTGG
TGCTGAAACAGCCCGACCTCGGCACCGCGCTGTTGATCGCCGCCGCCGGCTTCTTCGTGCTGTTCTTCGCCGGCCTACCG
TGGAAAGTCATTCTGGCCGGCGCGGTGATGGCCGCCGCCAGCCTGCCCATCGTCTGGAACCACCTGCACGACTACCAGCG
CAAGCGGGTGCTGACCCTGATCGACCCCACCACCGACCCGCTGGGCACCGGCTACCACATCATCCAGTCGATGATCGCCA
TCGGCTCCGGCGGCCCCTGGGGCAAGGGCTGGCTCAACGGCACCCAGACCCACCTGGACTACATCCCGGAGCGCACCACC
GACTTCATCTTCGCCGTCTATTCCGAAGAGTTCGGCCTGGCCGGCAACGCGGTGCTGCTGACGCTCTACCTGCTGATCCT
GAGCCGGGCGATGATGATCACCGCCAGCGCGCAGACGCTGTACGGCCGGCTGATGGCCGGATCGATCACCATGTCCTTCT
TCGTCTACGCCTTCGTCAACATGGGCATGGTGTCCGGCATCCTGCCGGTGGTCGGCGTGCCGCTGCCCTTCATGTCCTAC
GGCGGCACCGCCTCGGTCACGCTGTTCATCGGCATGGGCATGCTGATGGGCATCAGCAATCTGCGGCGCTGA

Upstream 100 bases:

>100_bases
ATGCTCAAGACCGTGCCGATGGAAAACGGAGACGTACGTGAAGACGCCGCTGATTAAGCACATCTGGCAGCAGATAAAAG
AGCCGCTGGACGGCTGGCTG

Downstream 100 bases:

>100_bases
GCGCCCCGCTCCGGAACCCTTGCCGAGCCGGCCTGCCCAAGCAGGCCGGTTTGTCCATCCGCCGCGCGCGGCTTGACGCC
GCCAACGCCGCTGCGGCATC

Product: rod shape-determining

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLFLGLIFAVSMVLLYSANNQSFDKIDNKLIYTAMALTVMWVIARMRPQSVMNFAPPIYVIGVLLLIAVHFKGITVNGST
RWLSLGVTRIQPSEILKIALPMMLAWFFQKYELSLRWWHYLIAAAIMLVPVGLVLKQPDLGTALLIAAAGFFVLFFAGLP
WKVILAGAVMAAASLPIVWNHLHDYQRKRVLTLIDPTTDPLGTGYHIIQSMIAIGSGGPWGKGWLNGTQTHLDYIPERTT
DFIFAVYSEEFGLAGNAVLLTLYLLILSRAMMITASAQTLYGRLMAGSITMSFFVYAFVNMGMVSGILPVVGVPLPFMSY
GGTASVTLFIGMGMLMGISNLRR

Sequences:

>Translated_343_residues
MLFLGLIFAVSMVLLYSANNQSFDKIDNKLIYTAMALTVMWVIARMRPQSVMNFAPPIYVIGVLLLIAVHFKGITVNGST
RWLSLGVTRIQPSEILKIALPMMLAWFFQKYELSLRWWHYLIAAAIMLVPVGLVLKQPDLGTALLIAAAGFFVLFFAGLP
WKVILAGAVMAAASLPIVWNHLHDYQRKRVLTLIDPTTDPLGTGYHIIQSMIAIGSGGPWGKGWLNGTQTHLDYIPERTT
DFIFAVYSEEFGLAGNAVLLTLYLLILSRAMMITASAQTLYGRLMAGSITMSFFVYAFVNMGMVSGILPVVGVPLPFMSY
GGTASVTLFIGMGMLMGISNLRR
>Mature_343_residues
MLFLGLIFAVSMVLLYSANNQSFDKIDNKLIYTAMALTVMWVIARMRPQSVMNFAPPIYVIGVLLLIAVHFKGITVNGST
RWLSLGVTRIQPSEILKIALPMMLAWFFQKYELSLRWWHYLIAAAIMLVPVGLVLKQPDLGTALLIAAAGFFVLFFAGLP
WKVILAGAVMAAASLPIVWNHLHDYQRKRVLTLIDPTTDPLGTGYHIIQSMIAIGSGGPWGKGWLNGTQTHLDYIPERTT
DFIFAVYSEEFGLAGNAVLLTLYLLILSRAMMITASAQTLYGRLMAGSITMSFFVYAFVNMGMVSGILPVVGVPLPFMSY
GGTASVTLFIGMGMLMGISNLRR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=50.5988023952096, Blast_Score=310, Evalue=7e-86,
Organism=Escherichia coli, GI1786277, Length=345, Percent_Identity=31.5942028985507, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 37772; Mature: 37772

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLGLIFAVSMVLLYSANNQSFDKIDNKLIYTAMALTVMWVIARMRPQSVMNFAPPIYV
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
IGVLLLIAVHFKGITVNGSTRWLSLGVTRIQPSEILKIALPMMLAWFFQKYELSLRWWHY
HHHHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAAAIMLVPVGLVLKQPDLGTALLIAAAGFFVLFFAGLPWKVILAGAVMAAASLPIVWN
HHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
HLHDYQRKRVLTLIDPTTDPLGTGYHIIQSMIAIGSGGPWGKGWLNGTQTHLDYIPERTT
HHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCH
DFIFAVYSEEFGLAGNAVLLTLYLLILSRAMMITASAQTLYGRLMAGSITMSFFVYAFVN
HHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMVSGILPVVGVPLPFMSYGGTASVTLFIGMGMLMGISNLRR
HHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFLGLIFAVSMVLLYSANNQSFDKIDNKLIYTAMALTVMWVIARMRPQSVMNFAPPIYV
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
IGVLLLIAVHFKGITVNGSTRWLSLGVTRIQPSEILKIALPMMLAWFFQKYELSLRWWHY
HHHHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAAAIMLVPVGLVLKQPDLGTALLIAAAGFFVLFFAGLPWKVILAGAVMAAASLPIVWN
HHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
HLHDYQRKRVLTLIDPTTDPLGTGYHIIQSMIAIGSGGPWGKGWLNGTQTHLDYIPERTT
HHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCH
DFIFAVYSEEFGLAGNAVLLTLYLLILSRAMMITASAQTLYGRLMAGSITMSFFVYAFVN
HHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMVSGILPVVGVPLPFMSYGGTASVTLFIGMGMLMGISNLRR
HHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]