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The map label for this gene is yafC [H]

Identifier: 34499745

GI number: 34499745

Start: 4629769

End: 4630689

Strand: Direct

Name: yafC [H]

Synonym: CV_4290

Alternate gene names: 34499745

Gene position: 4629769-4630689 (Clockwise)

Preceding gene: 34499744

Following gene: 34499749

Centisome position: 97.45

GC content: 61.24

Gene sequence:

>921_bases
ATGAATGCCGCCAGGTACGCCGAGCACCTTGCCATCTTTGTCGAAGTCGCGCGCGGGGGGTCGTTTTCAGCGGTCGCCCG
CCGCCACGGCGCGACGCCATCAACCATTACCCGAAAAATCGACATGCTGGAGGAGTTCGTCGGCACCAATCTGCTGGTTC
GCTCCACCAGAGCGCTGCTGCTGACCGAAGCGGGAGAAACACTGTTTGCCCGCGGAGTCAGCGTACTGGAAGCCTTGACC
GACATCCATAACGAGGTCATCGCCCTGAGCGACAGCATGTACGGCACGCTGCGCATCAGTTGTCTGCCGACTTTCGGCAA
ACTGCATGTCCTGCCTTGGCTGGCCGACTTGCAACAACGCCATCCCAGCATGCGCATTGATCTCGACCTCACCGAACGTC
TAACCAATCCATCGGTGGAGCGGCTGGATGCCGCCATTCGCATCGGCAAGCTCAAGGACAGTTCGCTGTTCGCCAAGCAG
ATCGGCACGCAACGCTGGGTGATCTGCGCCAGCCCCGACTACCTGCGCCAACGCGGCCATCCTTCCGATCTCGAAGACCT
GCGCCGGCTCCGGCTCATCGACAAGTTGCACGATCCTCATTCCATGTGCTGGAGACGACTGGTGGAAAAAGGCCATATAG
ACCAGATTGAGGCCGCTTTCCGTTGCGACGACTTCGAAGCCATGCGCCAAGCCGCGCTGTGCGGACTCGGCGCGGCTTTC
CTGCCGGACTGGGTGATAGCCCAAGACCTGGCCGCAGGCGCGCTGATTCGATTGTTCGATGATCCGGAAGGAAGGGAAGA
TGGCATTCACCTGGTGCGGGCCCTGCCCAAGATGTCGGCCAAGCTGGAGGTTTTCCACCAGGCCCTGAGCAACCATCTCG
GGCAAGTCCGCATCGGCGGATGCCTGCCCGCCTCCCGTTAA

Upstream 100 bases:

>100_bases
CGCTCATGATCCAATTGGCAAATGACTTTTGCGCAGGAATTCCAATAACATCAAAATGGATTAAACTCACCGATTCTTTC
TTGATGAGTACCGTTTCTGC

Downstream 100 bases:

>100_bases
ATCCGCTCAATCACCATAGCGATGCCCTGGCCTACGCCCACGCACATGGAACACAGCGCGTAGCGTCCCCCCGTCCGCGC
CAGGTGGTACACCGCGGTGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNAARYAEHLAIFVEVARGGSFSAVARRHGATPSTITRKIDMLEEFVGTNLLVRSTRALLLTEAGETLFARGVSVLEALT
DIHNEVIALSDSMYGTLRISCLPTFGKLHVLPWLADLQQRHPSMRIDLDLTERLTNPSVERLDAAIRIGKLKDSSLFAKQ
IGTQRWVICASPDYLRQRGHPSDLEDLRRLRLIDKLHDPHSMCWRRLVEKGHIDQIEAAFRCDDFEAMRQAALCGLGAAF
LPDWVIAQDLAAGALIRLFDDPEGREDGIHLVRALPKMSAKLEVFHQALSNHLGQVRIGGCLPASR

Sequences:

>Translated_306_residues
MNAARYAEHLAIFVEVARGGSFSAVARRHGATPSTITRKIDMLEEFVGTNLLVRSTRALLLTEAGETLFARGVSVLEALT
DIHNEVIALSDSMYGTLRISCLPTFGKLHVLPWLADLQQRHPSMRIDLDLTERLTNPSVERLDAAIRIGKLKDSSLFAKQ
IGTQRWVICASPDYLRQRGHPSDLEDLRRLRLIDKLHDPHSMCWRRLVEKGHIDQIEAAFRCDDFEAMRQAALCGLGAAF
LPDWVIAQDLAAGALIRLFDDPEGREDGIHLVRALPKMSAKLEVFHQALSNHLGQVRIGGCLPASR
>Mature_306_residues
MNAARYAEHLAIFVEVARGGSFSAVARRHGATPSTITRKIDMLEEFVGTNLLVRSTRALLLTEAGETLFARGVSVLEALT
DIHNEVIALSDSMYGTLRISCLPTFGKLHVLPWLADLQQRHPSMRIDLDLTERLTNPSVERLDAAIRIGKLKDSSLFAKQ
IGTQRWVICASPDYLRQRGHPSDLEDLRRLRLIDKLHDPHSMCWRRLVEKGHIDQIEAAFRCDDFEAMRQAALCGLGAAF
LPDWVIAQDLAAGALIRLFDDPEGREDGIHLVRALPKMSAKLEVFHQALSNHLGQVRIGGCLPASR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=32.421875, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789440, Length=264, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87081978, Length=263, Percent_Identity=29.6577946768061, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=26.4214046822742, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=272, Percent_Identity=31.9852941176471, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787128, Length=263, Percent_Identity=23.574144486692, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789173, Length=266, Percent_Identity=25.5639097744361, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786508, Length=278, Percent_Identity=26.2589928057554, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=32.2314049586777, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788706, Length=286, Percent_Identity=23.4265734265734, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=119, Percent_Identity=34.453781512605, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34111; Mature: 34111

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAARYAEHLAIFVEVARGGSFSAVARRHGATPSTITRKIDMLEEFVGTNLLVRSTRALL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHE
LTEAGETLFARGVSVLEALTDIHNEVIALSDSMYGTLRISCLPTFGKLHVLPWLADLQQR
EECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHC
HPSMRIDLDLTERLTNPSVERLDAAIRIGKLKDSSLFAKQIGTQRWVICASPDYLRQRGH
CCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCCHHHHHCCC
PSDLEDLRRLRLIDKLHDPHSMCWRRLVEKGHIDQIEAAFRCDDFEAMRQAALCGLGAAF
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LPDWVIAQDLAAGALIRLFDDPEGREDGIHLVRALPKMSAKLEVFHQALSNHLGQVRIGG
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
CLPASR
CCCCCC
>Mature Secondary Structure
MNAARYAEHLAIFVEVARGGSFSAVARRHGATPSTITRKIDMLEEFVGTNLLVRSTRALL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHE
LTEAGETLFARGVSVLEALTDIHNEVIALSDSMYGTLRISCLPTFGKLHVLPWLADLQQR
EECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHC
HPSMRIDLDLTERLTNPSVERLDAAIRIGKLKDSSLFAKQIGTQRWVICASPDYLRQRGH
CCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCCHHHHHCCC
PSDLEDLRRLRLIDKLHDPHSMCWRRLVEKGHIDQIEAAFRCDDFEAMRQAALCGLGAAF
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LPDWVIAQDLAAGALIRLFDDPEGREDGIHLVRALPKMSAKLEVFHQALSNHLGQVRIGG
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
CLPASR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]