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The map label for this gene is cutA [H]

Identifier: 34499706

GI number: 34499706

Start: 4587360

End: 4587617

Strand: Reverse

Name: cutA [H]

Synonym: CV_4251

Alternate gene names: 34499706

Gene position: 4587617-4587360 (Counterclockwise)

Preceding gene: 34499713

Following gene: 34499705

Centisome position: 96.56

GC content: 62.79

Gene sequence:

>258_bases
GTGACCGAGCAACTGGCCGCCTGCGTCAATATTCTGGCACCCTGCCGTTCAGTGTACCGCTGGCAGGGCGCGGTGGAGCA
GGCCGAGGAAATTCCGCTGCTGATCAAGACCCGCGCTGACGCGTATCCGCAACTGGAGGCCAAGCTGGCGGCGCTGCACC
CGTACCAGGTGCCGGAGATCGTCGCGCTGCCGCTGGCGCAGGGATTGCCCTCTTATCTCACATGGGTATCGAACAGCGTG
GTTTCAAGTGGCGAATAA

Upstream 100 bases:

>100_bases
GAGAACGCGCATCTTGAATCCGATTCCATCTAACGATTGTTTACTGGTTGTCTGCAACGCGCCGGACGCGGAAACCGCCG
AGCGCATCGCGACGACGCTG

Downstream 100 bases:

>100_bases
TCACGGGCCGGTTTGTTCCGACTGTTTTCCGGCCGGTTTCGTTCCCATGATTAAGAGGCGGACGGGGAAATTTTTTCGCG
ATACAGCTTGACTCGACTGA

Product: periplasmic divalent cation tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MTEQLAACVNILAPCRSVYRWQGAVEQAEEIPLLIKTRADAYPQLEAKLAALHPYQVPEIVALPLAQGLPSYLTWVSNSV
VSSGE

Sequences:

>Translated_85_residues
MTEQLAACVNILAPCRSVYRWQGAVEQAEEIPLLIKTRADAYPQLEAKLAALHPYQVPEIVALPLAQGLPSYLTWVSNSV
VSSGE
>Mature_84_residues
TEQLAACVNILAPCRSVYRWQGAVEQAEEIPLLIKTRADAYPQLEAKLAALHPYQVPEIVALPLAQGLPSYLTWVSNSVV
SSGE

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62198241, Length=74, Percent_Identity=41.8918918918919, Blast_Score=73, Evalue=5e-14,
Organism=Homo sapiens, GI62526024, Length=74, Percent_Identity=41.8918918918919, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI62526022, Length=74, Percent_Identity=41.8918918918919, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI7706244, Length=74, Percent_Identity=41.8918918918919, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI62526026, Length=74, Percent_Identity=41.8918918918919, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790579, Length=80, Percent_Identity=36.25, Blast_Score=65, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32565476, Length=83, Percent_Identity=34.9397590361446, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641937, Length=82, Percent_Identity=40.2439024390244, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 9279; Mature: 9148

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQLAACVNILAPCRSVYRWQGAVEQAEEIPLLIKTRADAYPQLEAKLAALHPYQVPEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCHHH
VALPLAQGLPSYLTWVSNSVVSSGE
HHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEQLAACVNILAPCRSVYRWQGAVEQAEEIPLLIKTRADAYPQLEAKLAALHPYQVPEI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCHHH
VALPLAQGLPSYLTWVSNSVVSSGE
HHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA