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The map label for this gene is mcp4 [H]

Identifier: 34499610

GI number: 34499610

Start: 4495672

End: 4497315

Strand: Reverse

Name: mcp4 [H]

Synonym: CV_4155

Alternate gene names: 34499610

Gene position: 4497315-4495672 (Counterclockwise)

Preceding gene: 34499611

Following gene: 34499598

Centisome position: 94.66

GC content: 66.06

Gene sequence:

>1644_bases
ATGGCGAATGCAGGCTTGAGCCTGAAGACCCGGCTGATCGGGTTGATGGCCTTGGTGGTGGTCGTGGTGTGCGGCCTGGG
CGTGGTATCGGTGTACAACCAGCGCCAGGTGATGCTGAAAGACCGGCAGGACAAGGTGCGCAACCTGGTGCAGAGCGCCG
TGGGCCTGGTTTCCAGTTACGAGAAGATGGTGGAGAGCGGCAAGATCGGCGAGGCCGACGCCAAGCGCATGCTATCCAAG
GCCTTGAGCGCCATGCATTACGAAAAGGCGGATTACTTTTTCGCCTATGACGCCGATTGGAATTACGTCGCGCACGGCGC
CAAGCCGGAGCTGATCGGCAAGAACCTGGCCGGGGTCAAGGACCCGAACGGCGTCGAGTTGAAGACCCTGTTCCAGAACG
CGATCTCGTCGCCCGGCGGCGGCGGCTACGGCGAATACGTGTGGAGCAAGCCCGGCTTCGATCAGCCGCAGCCCAAGATC
TCTTACGTCACCACCACGCCGAAATGGCATTGGATCGTCGGCACCGGCATCTACCTCGACGACGTCGCGGCGGCCTTCCG
CCACGAGCTGCTGTGGCTGGGCGGGGTGCTGGCGGCGGCGCTGCTAGTGCTGCTGGGCATGGGCGGCATGATATTGCGCA
ATGTGCTGAGCCAACTGGGCGGCGATCCGCAGGATACGGTGGCGGTGGTCAAGCGCATCGCCGCCGGCCATCTGGACGAG
GAGGTGGCGGTGAAGGAGGGGGACGGGGACAGCCTGATGTCCGCGGTGGGCGCGATGCAACGGGAACTGGAGCGGCTGGT
GCGCGACATCATCGCCGGCGCCAACCAGCTGTCCCAGGTCAGCAGCAAGGTGACCGGCGAGGCGGAGGCGGTCGGCCGCG
GCTCGGAGCAGCAGAGCGCGGCGGCCACCGCGATGGCGGCGTCTATCGAGCAGTTGACGGTCAGCGTCAACCATATTTCC
GACCGCTCGCAGGACGCGCGCAACCTGGCCAACGAATCCGGCACGCTGTCCAAGAGCGGCGGCGCGGTGATCGCCGAAGC
GGTCAGCGAGATGCGGCGCATCAACGACGCGGTCGATCAGACCTCGGGCATCATCACCAGCCTGGCCGACAAGACCCAGA
CCATTTCCAGCATCATGCAAGTGATCAAGGACATCGCCGACCAGACCAATCTGCTGGCGCTGAACGCCGCGATCGAGGCG
GCGCGGGCCGGCGAGATGGGCCGGGGCTTCGCGGTGGTGGCGGACGAGGTGCGCAAGCTGTCCGAACGCACCGCGCAGGC
GACGCAGGAAATCGCCAGCATGATCCAGGACGTGCAGCAGGGCGCGGAGCATTCGCGCCACAGCATGGAAGAGGCGGTGG
GCAGGGTGAAGGCGGGGCTGGACCTGGCTGAGCAGGCAGGCTCCGAGATCGCCCGCATCCAGGACAGCGCCAACGGCGTG
GTAGCGGTGATCGGCGACATCTCCCACGCGCTGCAGGAGCAGAGCGCGGCCAGCCAGGCCATCGCCCAGCATGTCGAGCA
GATCGCCCACAGCGCCACCAGCAACGCTTCTGCGTCGCAGTCCGCGTCGCAGGCCATCCATAATATGCACCAGCTGGCAG
CCAACCTGCGGCAACTGGTGTCGCGTTTCTCGGTACGCGGCTAG

Upstream 100 bases:

>100_bases
CGGCGTGGCGGCTGGTTGGATCGGTTTCTAGAATGGTTTTGTAGCATAACTATCAAAATAAGCACGAATCAATGCGTGCC
GGTTGGGGAAGGAGCGGGAA

Downstream 100 bases:

>100_bases
CTCAGCGCCGGAAATGGAAAAAGGCCCGGCGGTGCGCATCGCCGGGCCTTTTTCTTGTTCAATGCCAGCCAGGGCTAATG
CTGGCCTCGCCGGCGCCAGC

Product: methyl-accepting chemotaxis transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MANAGLSLKTRLIGLMALVVVVVCGLGVVSVYNQRQVMLKDRQDKVRNLVQSAVGLVSSYEKMVESGKIGEADAKRMLSK
ALSAMHYEKADYFFAYDADWNYVAHGAKPELIGKNLAGVKDPNGVELKTLFQNAISSPGGGGYGEYVWSKPGFDQPQPKI
SYVTTTPKWHWIVGTGIYLDDVAAAFRHELLWLGGVLAAALLVLLGMGGMILRNVLSQLGGDPQDTVAVVKRIAAGHLDE
EVAVKEGDGDSLMSAVGAMQRELERLVRDIIAGANQLSQVSSKVTGEAEAVGRGSEQQSAAATAMAASIEQLTVSVNHIS
DRSQDARNLANESGTLSKSGGAVIAEAVSEMRRINDAVDQTSGIITSLADKTQTISSIMQVIKDIADQTNLLALNAAIEA
ARAGEMGRGFAVVADEVRKLSERTAQATQEIASMIQDVQQGAEHSRHSMEEAVGRVKAGLDLAEQAGSEIARIQDSANGV
VAVIGDISHALQEQSAASQAIAQHVEQIAHSATSNASASQSASQAIHNMHQLAANLRQLVSRFSVRG

Sequences:

>Translated_547_residues
MANAGLSLKTRLIGLMALVVVVVCGLGVVSVYNQRQVMLKDRQDKVRNLVQSAVGLVSSYEKMVESGKIGEADAKRMLSK
ALSAMHYEKADYFFAYDADWNYVAHGAKPELIGKNLAGVKDPNGVELKTLFQNAISSPGGGGYGEYVWSKPGFDQPQPKI
SYVTTTPKWHWIVGTGIYLDDVAAAFRHELLWLGGVLAAALLVLLGMGGMILRNVLSQLGGDPQDTVAVVKRIAAGHLDE
EVAVKEGDGDSLMSAVGAMQRELERLVRDIIAGANQLSQVSSKVTGEAEAVGRGSEQQSAAATAMAASIEQLTVSVNHIS
DRSQDARNLANESGTLSKSGGAVIAEAVSEMRRINDAVDQTSGIITSLADKTQTISSIMQVIKDIADQTNLLALNAAIEA
ARAGEMGRGFAVVADEVRKLSERTAQATQEIASMIQDVQQGAEHSRHSMEEAVGRVKAGLDLAEQAGSEIARIQDSANGV
VAVIGDISHALQEQSAASQAIAQHVEQIAHSATSNASASQSASQAIHNMHQLAANLRQLVSRFSVRG
>Mature_546_residues
ANAGLSLKTRLIGLMALVVVVVCGLGVVSVYNQRQVMLKDRQDKVRNLVQSAVGLVSSYEKMVESGKIGEADAKRMLSKA
LSAMHYEKADYFFAYDADWNYVAHGAKPELIGKNLAGVKDPNGVELKTLFQNAISSPGGGGYGEYVWSKPGFDQPQPKIS
YVTTTPKWHWIVGTGIYLDDVAAAFRHELLWLGGVLAAALLVLLGMGGMILRNVLSQLGGDPQDTVAVVKRIAAGHLDEE
VAVKEGDGDSLMSAVGAMQRELERLVRDIIAGANQLSQVSSKVTGEAEAVGRGSEQQSAAATAMAASIEQLTVSVNHISD
RSQDARNLANESGTLSKSGGAVIAEAVSEMRRINDAVDQTSGIITSLADKTQTISSIMQVIKDIADQTNLLALNAAIEAA
RAGEMGRGFAVVADEVRKLSERTAQATQEIASMIQDVQQGAEHSRHSMEEAVGRVKAGLDLAEQAGSEIARIQDSANGVV
AVIGDISHALQEQSAASQAIAQHVEQIAHSATSNASASQSASQAIHNMHQLAANLRQLVSRFSVRG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=384, Percent_Identity=32.5520833333333, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1788194, Length=315, Percent_Identity=34.6031746031746, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788195, Length=321, Percent_Identity=34.5794392523364, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1787690, Length=364, Percent_Identity=33.5164835164835, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789453, Length=272, Percent_Identity=28.6764705882353, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57916; Mature: 57785

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAGLSLKTRLIGLMALVVVVVCGLGVVSVYNQRQVMLKDRQDKVRNLVQSAVGLVSSY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMVESGKIGEADAKRMLSKALSAMHYEKADYFFAYDADWNYVAHGAKPELIGKNLAGVK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHCCCCCCCC
DPNGVELKTLFQNAISSPGGGGYGEYVWSKPGFDQPQPKISYVTTTPKWHWIVGTGIYLD
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHH
DVAAAFRHELLWLGGVLAAALLVLLGMGGMILRNVLSQLGGDPQDTVAVVKRIAAGHLDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
EVAVKEGDGDSLMSAVGAMQRELERLVRDIIAGANQLSQVSSKVTGEAEAVGRGSEQQSA
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHCCCCHHHHH
AATAMAASIEQLTVSVNHISDRSQDARNLANESGTLSKSGGAVIAEAVSEMRRINDAVDQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TSGIITSLADKTQTISSIMQVIKDIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SERTAQATQEIASMIQDVQQGAEHSRHSMEEAVGRVKAGLDLAEQAGSEIARIQDSANGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHCCCCE
VAVIGDISHALQEQSAASQAIAQHVEQIAHSATSNASASQSASQAIHNMHQLAANLRQLV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRFSVRG
HHHCCCC
>Mature Secondary Structure 
ANAGLSLKTRLIGLMALVVVVVCGLGVVSVYNQRQVMLKDRQDKVRNLVQSAVGLVSSY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMVESGKIGEADAKRMLSKALSAMHYEKADYFFAYDADWNYVAHGAKPELIGKNLAGVK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHCCCCCCCC
DPNGVELKTLFQNAISSPGGGGYGEYVWSKPGFDQPQPKISYVTTTPKWHWIVGTGIYLD
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHH
DVAAAFRHELLWLGGVLAAALLVLLGMGGMILRNVLSQLGGDPQDTVAVVKRIAAGHLDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
EVAVKEGDGDSLMSAVGAMQRELERLVRDIIAGANQLSQVSSKVTGEAEAVGRGSEQQSA
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHCCCCHHHHH
AATAMAASIEQLTVSVNHISDRSQDARNLANESGTLSKSGGAVIAEAVSEMRRINDAVDQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TSGIITSLADKTQTISSIMQVIKDIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SERTAQATQEIASMIQDVQQGAEHSRHSMEEAVGRVKAGLDLAEQAGSEIARIQDSANGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHCCCCE
VAVIGDISHALQEQSAASQAIAQHVEQIAHSATSNASASQSASQAIHNMHQLAANLRQLV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRFSVRG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]