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The map label for this gene is aidB [H]

Identifier: 34499591

GI number: 34499591

Start: 4476742

End: 4478385

Strand: Reverse

Name: aidB [H]

Synonym: CV_4136

Alternate gene names: 34499591

Gene position: 4478385-4476742 (Counterclockwise)

Preceding gene: 34499594

Following gene: 34499587

Centisome position: 94.26

GC content: 70.56

Gene sequence:

>1644_bases
ATGAGCTGGCAAACGCATGAAGTGAACAATCAGTACGAGGAATTGCAGGACTACAATCCGTTCGAAACCGATGCGGCGTT
GAAGGAGGCGGTGATCCACGCCGGCGCGGGCTGGGCGCTGCCCTGGCTGGCCGAGTACGGCGAGCGGCTGGGACGCGCGG
AAACGTTCGAGCTGGCCGCGCAGGCCAACCGTTTCGCGCCGCAGCTGCAGGCTTTCGACCGTCGCGGCCGCCGCATCGAC
CGCGTCGATTTCCACCCCTCCTGGCACGATCTCCTGGCGTTGTACCGCTCGCAGGGGCTGGTGTCGCTGCCGTTCGACAG
CGAGCGTCCCGGGCGCTGGGCGGCTTTTCTCGCCGGCTTCTACCTGCACGGCCAGGTGGAGGCGGGAACCTTGTGCCCGG
CCACCATGACCCAGGCGGCGATTCCGTTGCTGAAGCGGGAGCCGGCGCTGTGGGCGCAACTGGGCGACAAGCTGCTCAGC
CGCGAGCATGACGCGCGCGACCTGCCGGCGGAGCGCAAGACCGCGATCTGGCTGGGCATGGGCATGACCGAGAAGCAGGG
CGGCTCGGATGTGCGCTCCAACACCTCCACCGCGACGCCGACCGGCGCAGGCGGCCGCGGCGGAGAATACACGCTGCGCG
GCCACAAGTGGTTCTTCTCCGCGCCGATGAGCGACGCCCACCTGGTGGTGGCGCAGCTGCGCGACGGCGGGCCGTCCTGC
TTCTACGTGCCGCGCTGGCGGCCGGACGGCAGCCGCAACGCGGTGGCGATACAACGCTTGAAGGACAAGGTGGGCAACCG
CAGCAATGCCAGCAGCGAGGTGGAGTTCCATGATGCTTGGGGCGTGCTGATCGGCGAGCCCGGCCGCGGCATTCCCACCA
TCATCGAGATGGCCACCTACACCCGGCTCAGCTGCGTGATCGGCAGCGCGGCGCTGATCCGCCAGGGCCTGGTCCAGGCG
ATCGCCTACGCCCGCCGCCGCGTCGCCTTCGGCAAGCGCCTGGCCGAACAGCCGCTGATGCGCGGGGTGCTGGCCGATCT
GGCGCTGGAGAGCGAGGCCGCGCTGTGCCTGGCGGCTCGGCTGGCCGAGGGATTCGAGAACGACGAGCCGGCATGGAAGC
GCATCGTCACGCCGGCCGCCAAGTTCTGGGTGTGCAAGCGCGCGGTGGAGGCAGTCGGCGAGACCATGGAGGTATTCGGC
GGCAATGGCTACGTCGATGACGGGCCGATGGCGCGGCTGTTCCGCGAAGCGCCGGTCAACTCCATCTGGGAAGGTTCGGG
CAATGTGATGTGCCTGGACGTGATGCGGGCGCTGCAGCGGGAGCCAGAGGCCTGGCAGCGGCTGCAACAGGAGCTGGCGG
CGCTCGCGGGCGGCGACCGGCGGCTGAGCGCCGCGCTGGCGGATTTGCGGTCGATGGCGTCGCTGTCGCCACCACAGCTG
GAGGGCCTGGGCCGCCGCTTCGCCCAGCAACTGGCGCTGACCGTCCAAGGCTGCCTGCTGCGCGGGCGCGCGCCGGCGGC
GGTGGCCGACGGCTTCATCGCCAGCAGGCTGGCCGATGGGCTGTGGGGAAGGGTGGCGGGCGCGCTGGACGCTAGGGCGG
CCGGCGCGGACTACCTGCTGGAACGCGCGCTGCCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GTCGCAGGTTTTTTTGCCGGGCCGTCCATTTATACTGTTCGCATCGCCAGTTCGATAGCGGCGGCCATCGGCGGGCTGGC
ATTCATCCGGGAGTCTGGAC

Downstream 100 bases:

>100_bases
GCGCATGCCGAGCGCCGCGCTGTGGACAAGATTCGCTGAATAGACCTGTTGTGGATAAGTCGGCGGCTCAGTCCTCCCGC
GCCGCGGCTTCCACCCGGTT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSWQTHEVNNQYEELQDYNPFETDAALKEAVIHAGAGWALPWLAEYGERLGRAETFELAAQANRFAPQLQAFDRRGRRID
RVDFHPSWHDLLALYRSQGLVSLPFDSERPGRWAAFLAGFYLHGQVEAGTLCPATMTQAAIPLLKREPALWAQLGDKLLS
REHDARDLPAERKTAIWLGMGMTEKQGGSDVRSNTSTATPTGAGGRGGEYTLRGHKWFFSAPMSDAHLVVAQLRDGGPSC
FYVPRWRPDGSRNAVAIQRLKDKVGNRSNASSEVEFHDAWGVLIGEPGRGIPTIIEMATYTRLSCVIGSAALIRQGLVQA
IAYARRRVAFGKRLAEQPLMRGVLADLALESEAALCLAARLAEGFENDEPAWKRIVTPAAKFWVCKRAVEAVGETMEVFG
GNGYVDDGPMARLFREAPVNSIWEGSGNVMCLDVMRALQREPEAWQRLQQELAALAGGDRRLSAALADLRSMASLSPPQL
EGLGRRFAQQLALTVQGCLLRGRAPAAVADGFIASRLADGLWGRVAGALDARAAGADYLLERALPAA

Sequences:

>Translated_547_residues
MSWQTHEVNNQYEELQDYNPFETDAALKEAVIHAGAGWALPWLAEYGERLGRAETFELAAQANRFAPQLQAFDRRGRRID
RVDFHPSWHDLLALYRSQGLVSLPFDSERPGRWAAFLAGFYLHGQVEAGTLCPATMTQAAIPLLKREPALWAQLGDKLLS
REHDARDLPAERKTAIWLGMGMTEKQGGSDVRSNTSTATPTGAGGRGGEYTLRGHKWFFSAPMSDAHLVVAQLRDGGPSC
FYVPRWRPDGSRNAVAIQRLKDKVGNRSNASSEVEFHDAWGVLIGEPGRGIPTIIEMATYTRLSCVIGSAALIRQGLVQA
IAYARRRVAFGKRLAEQPLMRGVLADLALESEAALCLAARLAEGFENDEPAWKRIVTPAAKFWVCKRAVEAVGETMEVFG
GNGYVDDGPMARLFREAPVNSIWEGSGNVMCLDVMRALQREPEAWQRLQQELAALAGGDRRLSAALADLRSMASLSPPQL
EGLGRRFAQQLALTVQGCLLRGRAPAAVADGFIASRLADGLWGRVAGALDARAAGADYLLERALPAA
>Mature_546_residues
SWQTHEVNNQYEELQDYNPFETDAALKEAVIHAGAGWALPWLAEYGERLGRAETFELAAQANRFAPQLQAFDRRGRRIDR
VDFHPSWHDLLALYRSQGLVSLPFDSERPGRWAAFLAGFYLHGQVEAGTLCPATMTQAAIPLLKREPALWAQLGDKLLSR
EHDARDLPAERKTAIWLGMGMTEKQGGSDVRSNTSTATPTGAGGRGGEYTLRGHKWFFSAPMSDAHLVVAQLRDGGPSCF
YVPRWRPDGSRNAVAIQRLKDKVGNRSNASSEVEFHDAWGVLIGEPGRGIPTIIEMATYTRLSCVIGSAALIRQGLVQAI
AYARRRVAFGKRLAEQPLMRGVLADLALESEAALCLAARLAEGFENDEPAWKRIVTPAAKFWVCKRAVEAVGETMEVFGG
NGYVDDGPMARLFREAPVNSIWEGSGNVMCLDVMRALQREPEAWQRLQQELAALAGGDRRLSAALADLRSMASLSPPQLE
GLGRRFAQQLALTVQGCLLRGRAPAAVADGFIASRLADGLWGRVAGALDARAAGADYLLERALPAA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=267, Percent_Identity=27.7153558052434, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI226958412, Length=270, Percent_Identity=25.5555555555556, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4501859, Length=364, Percent_Identity=24.7252747252747, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI226958414, Length=270, Percent_Identity=25.5555555555556, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4557231, Length=268, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI187960098, Length=268, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7656849, Length=271, Percent_Identity=25.830258302583, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=504, Percent_Identity=48.015873015873, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI87081958, Length=258, Percent_Identity=24.031007751938, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786223, Length=270, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=500, Percent_Identity=29.8, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI86563383, Length=500, Percent_Identity=29.8, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17538396, Length=290, Percent_Identity=26.8965517241379, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=305, Percent_Identity=26.2295081967213, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=276, Percent_Identity=26.8115942028986, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=271, Percent_Identity=25.830258302583, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=270, Percent_Identity=24.8148148148148, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=263, Percent_Identity=24.3346007604563, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=270, Percent_Identity=24.8148148148148, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=342, Percent_Identity=26.0233918128655, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=269, Percent_Identity=27.5092936802974, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646207, Length=268, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355753, Length=398, Percent_Identity=21.608040201005, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24660351, Length=272, Percent_Identity=27.9411764705882, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59786; Mature: 59654

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQTHEVNNQYEELQDYNPFETDAALKEAVIHAGAGWALPWLAEYGERLGRAETFELAA
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
QANRFAPQLQAFDRRGRRIDRVDFHPSWHDLLALYRSQGLVSLPFDSERPGRWAAFLAGF
HHHHHHHHHHHHHHCCCEECCEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHH
YLHGQVEAGTLCPATMTQAAIPLLKREPALWAQLGDKLLSREHDARDLPAERKTAIWLGM
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
GMTEKQGGSDVRSNTSTATPTGAGGRGGEYTLRGHKWFFSAPMSDAHLVVAQLRDGGPSC
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCHHEEEEECCCCCCCE
FYVPRWRPDGSRNAVAIQRLKDKVGNRSNASSEVEFHDAWGVLIGEPGRGIPTIIEMATY
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHH
TRLSCVIGSAALIRQGLVQAIAYARRRVAFGKRLAEQPLMRGVLADLALESEAALCLAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEGFENDEPAWKRIVTPAAKFWVCKRAVEAVGETMEVFGGNGYVDDGPMARLFREAPVN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
SIWEGSGNVMCLDVMRALQREPEAWQRLQQELAALAGGDRRLSAALADLRSMASLSPPQL
HHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
EGLGRRFAQQLALTVQGCLLRGRAPAAVADGFIASRLADGLWGRVAGALDARAAGADYLL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ERALPAA
HHCCCCC
>Mature Secondary Structure 
SWQTHEVNNQYEELQDYNPFETDAALKEAVIHAGAGWALPWLAEYGERLGRAETFELAA
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
QANRFAPQLQAFDRRGRRIDRVDFHPSWHDLLALYRSQGLVSLPFDSERPGRWAAFLAGF
HHHHHHHHHHHHHHCCCEECCEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHH
YLHGQVEAGTLCPATMTQAAIPLLKREPALWAQLGDKLLSREHDARDLPAERKTAIWLGM
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
GMTEKQGGSDVRSNTSTATPTGAGGRGGEYTLRGHKWFFSAPMSDAHLVVAQLRDGGPSC
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCHHEEEEECCCCCCCE
FYVPRWRPDGSRNAVAIQRLKDKVGNRSNASSEVEFHDAWGVLIGEPGRGIPTIIEMATY
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHH
TRLSCVIGSAALIRQGLVQAIAYARRRVAFGKRLAEQPLMRGVLADLALESEAALCLAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEGFENDEPAWKRIVTPAAKFWVCKRAVEAVGETMEVFGGNGYVDDGPMARLFREAPVN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
SIWEGSGNVMCLDVMRALQREPEAWQRLQQELAALAGGDRRLSAALADLRSMASLSPPQL
HHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
EGLGRRFAQQLALTVQGCLLRGRAPAAVADGFIASRLADGLWGRVAGALDARAAGADYLL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ERALPAA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]