Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 34499518

GI number: 34499518

Start: 4393488

End: 4394303

Strand: Direct

Name: plsC [H]

Synonym: CV_4063

Alternate gene names: 34499518

Gene position: 4393488-4394303 (Clockwise)

Preceding gene: 34499517

Following gene: 34499523

Centisome position: 92.47

GC content: 68.14

Gene sequence:

>816_bases
TTGAAGTCACACGCCACCACTACATTCGCCACCCGCTGCGGCCGCGTGACGCGCCTGCTCGGCCATCTGGCCGTGGGGGT
GTTCATCGTCGCCACCCGCTATTCCCGCCTGGCCCAGGCCGAGCGCGCGGTCGTCACCCGCCGCTGGGCGCAGCACGCGC
TGAAGATTCTCGGGGTCAGCATCAAGGTGCAGGGCGTCAATCCGGGCTTTTATCCGCCCAACACCCTGCTGGTCGCCAAC
CACGTGTCCTGGCTGGACATCGTGGCATTGAACAGCTGCACCGTGTCGCGCTTCGTCGCCAAGCGCGAAATCCGCAAATG
GCCGCTGATAGGCTGGCTGGCCTACGTGGCCGGCACGCTGTTCATCGACCGGGGCAACCGCCGCGACGCCAGCCGCGTCA
ACCAGATCCTGGCCGAGGCGATGCAGAACGGCGGCTGCATGGCGGTCTTCCCCGAAGCCACGACATCCGACGGCAGCGGC
CTGCTGCCGTTCAAGGCCTCGCTGTTCGAGGCCGCGCTGCTGTCCGGCGGCACCGTGCAGCCGGTATCGCTGCGCTACCA
GCGGCCGGACGGCAGCCTGCTGCGCGAGGCCGCCTACATCGACGACATCTCGCTGCTGCAGAGCATAGGCAAGGTATTGA
GCGTGCCGCAGATCGAGGTGGAAATCAGCTACGGCCAGCCGCTGAAAGCCGGCGAAGCCGGCCTGGACAACCGCTTCCTG
CTGGCCGAACAGGCCCGCAGCGAGGTGGCCCGCGGCCTGCGGCTGTCGCTGGAAGAACAGCCGCAACCGGTTCCGGCGGC
GGAAACCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCAAATCCGCCAGGGCCAGCGCAGCACTTACTATTGCCCGCTGTGCCAGCCGTGATAGAGTGGCGGCCTGTCATCCCTCA
GACTTGAAACCGTAACCATC

Downstream 100 bases:

>100_bases
ACGCTCAGCGCGACAGGCGCTGGCTCAGGCCTTCGTAGAGATCGTCGCCCAGCCGGGTATAGCCGGGCGCGGTGAAGTGG
ACCATGTCCGGGCGGCCCAG

Product: 1-acylglycerol-3-phosphate O-acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKSHATTTFATRCGRVTRLLGHLAVGVFIVATRYSRLAQAERAVVTRRWAQHALKILGVSIKVQGVNPGFYPPNTLLVAN
HVSWLDIVALNSCTVSRFVAKREIRKWPLIGWLAYVAGTLFIDRGNRRDASRVNQILAEAMQNGGCMAVFPEATTSDGSG
LLPFKASLFEAALLSGGTVQPVSLRYQRPDGSLLREAAYIDDISLLQSIGKVLSVPQIEVEISYGQPLKAGEAGLDNRFL
LAEQARSEVARGLRLSLEEQPQPVPAAETGA

Sequences:

>Translated_271_residues
MKSHATTTFATRCGRVTRLLGHLAVGVFIVATRYSRLAQAERAVVTRRWAQHALKILGVSIKVQGVNPGFYPPNTLLVAN
HVSWLDIVALNSCTVSRFVAKREIRKWPLIGWLAYVAGTLFIDRGNRRDASRVNQILAEAMQNGGCMAVFPEATTSDGSG
LLPFKASLFEAALLSGGTVQPVSLRYQRPDGSLLREAAYIDDISLLQSIGKVLSVPQIEVEISYGQPLKAGEAGLDNRFL
LAEQARSEVARGLRLSLEEQPQPVPAAETGA
>Mature_271_residues
MKSHATTTFATRCGRVTRLLGHLAVGVFIVATRYSRLAQAERAVVTRRWAQHALKILGVSIKVQGVNPGFYPPNTLLVAN
HVSWLDIVALNSCTVSRFVAKREIRKWPLIGWLAYVAGTLFIDRGNRRDASRVNQILAEAMQNGGCMAVFPEATTSDGSG
LLPFKASLFEAALLSGGTVQPVSLRYQRPDGSLLREAAYIDDISLLQSIGKVLSVPQIEVEISYGQPLKAGEAGLDNRFL
LAEQARSEVARGLRLSLEEQPQPVPAAETGA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320151, Length=137, Percent_Identity=36.4963503649635, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364648, Length=133, Percent_Identity=32.3308270676692, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582856, Length=133, Percent_Identity=32.3308270676692, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582854, Length=133, Percent_Identity=32.3308270676692, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 29420; Mature: 29420

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHATTTFATRCGRVTRLLGHLAVGVFIVATRYSRLAQAERAVVTRRWAQHALKILGVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IKVQGVNPGFYPPNTLLVANHVSWLDIVALNSCTVSRFVAKREIRKWPLIGWLAYVAGTL
EEEEECCCCCCCCCEEEEECCCCCHHHHEECCHHHHHHHHHHHHHHCCHHHHHHHHHHEE
FIDRGNRRDASRVNQILAEAMQNGGCMAVFPEATTSDGSGLLPFKASLFEAALLSGGTVQ
EEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
PVSLRYQRPDGSLLREAAYIDDISLLQSIGKVLSVPQIEVEISYGQPLKAGEAGLDNRFL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEE
LAEQARSEVARGLRLSLEEQPQPVPAAETGA
HHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSHATTTFATRCGRVTRLLGHLAVGVFIVATRYSRLAQAERAVVTRRWAQHALKILGVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IKVQGVNPGFYPPNTLLVANHVSWLDIVALNSCTVSRFVAKREIRKWPLIGWLAYVAGTL
EEEEECCCCCCCCCEEEEECCCCCHHHHEECCHHHHHHHHHHHHHHCCHHHHHHHHHHEE
FIDRGNRRDASRVNQILAEAMQNGGCMAVFPEATTSDGSGLLPFKASLFEAALLSGGTVQ
EEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
PVSLRYQRPDGSLLREAAYIDDISLLQSIGKVLSVPQIEVEISYGQPLKAGEAGLDNRFL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEE
LAEQARSEVARGLRLSLEEQPQPVPAAETGA
HHHHHHHHHHHHHEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8748025 [H]