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The map label for this gene is engD [H]

Identifier: 34499510

GI number: 34499510

Start: 4386013

End: 4387104

Strand: Reverse

Name: engD [H]

Synonym: CV_4055

Alternate gene names: 34499510

Gene position: 4387104-4386013 (Counterclockwise)

Preceding gene: 34499511

Following gene: 34499509

Centisome position: 92.34

GC content: 64.47

Gene sequence:

>1092_bases
ATGAGTCTGAAATGCGGTATCGTCGGCTTGCCCAATGTCGGCAAGTCCACCCTGTTTAACGCGCTGACCAAGGCCGGCAT
CGAAGCCGCCAACTACCCGTTCTGCACCATCGAGCCGAACGTAGGCATCGTCGAGGTGCCGGATCACCGCCTGGGCGAGC
TGGCCAAGATCATCAACCCGCAGAAAATCCAGCCGGCCATCGTCGAATTCGTCGACATCGCCGGCCTGGTGGCGGGCGCG
TCCAAGGGCGAGGGTCTGGGCAACCAGTTCCTGGCCAACATCCGCGAGACCGACGCCATCGTCAACGTGGTGCGTTGCTT
CGATGATCCGAACATCGTGCACGTGGCGGGCAAGGTTGACCCGATCGCCGACATCGAGACCATCCTGACCGAGCTGGCGC
TGGCCGACCTGTCCGCCGTGGAGAAAGCCATCGCCCGCGAAGGCAAGAAGGCCAAGGCCGGCGACAAGGACGCGCGCGCG
CTGATCGCCATCCTGGAAAAACTGGTGCCGCACCTGAACGAAGGCAAGCCGGCGCGCTCGCTGGGCCTGTCCGACGAGGA
CAAGGCGCTGATCAAGCCGCTGTGCCTGCTGACCATCAAGCCGGCCATGTACGTGGCCAACGTGGCCGAAGACGGCTTCA
GCGATAATCCGCTGCTGGCCAAGGTGGAGGAGTACGCCGCCAAGGAAGGCGCGCCGGTCGTCGCGCTGTGCGCGGCCATC
GAGTCCGAGATCGCCGAACTGGAAGACGCCGACAAGGCCGAGTTCCTGGAAACGCTGGGCCTGGAAGAGCCGGGTCTGGA
TCGCCTGATCCGCGCCGGCTACAAGCTGCTGGGCCTGCAAACCTACTTCACCGCCGGCGTGAAGGAAGTGCGCGCCTGGA
CCATCCATGTGGGCGACACCGCGCCGCAGGCCGCCGGCGTCATCCACACCGACTTCGAGCGCGGCTTCATCCGCGCGCAA
ACAATCTCCTTCCAGGACTTCGTCACGCTGGGCGGCGAGGCCAAGGCCAAGGAGGCCGGCAAGATGCGCGCCGAAGGCAA
GGATTACGTGGTGCAGGACGGCGACGTGATGAACTTCCTGTTCAACGTTTAA

Upstream 100 bases:

>100_bases
CGATGAAGGCGCTGCACACCGAAGCCAAGTGATCGCGGGCTGGCAGTCGGACCGGCTGCCGCCATAATGGATTGAAATAC
GAAAGTTTAGGAAAACAGTC

Downstream 100 bases:

>100_bases
CCATCAGACTGAACGATATAAGGCCTCTTCAAATAAGTAAGAGGACGATGGACGAGGGGTGCGTGATTGCATTTCTCGTC
TGGGTGGATAATGGGGAGTG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVEVPDHRLGELAKIINPQKIQPAIVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAIVNVVRCFDDPNIVHVAGKVDPIADIETILTELALADLSAVEKAIAREGKKAKAGDKDARA
LIAILEKLVPHLNEGKPARSLGLSDEDKALIKPLCLLTIKPAMYVANVAEDGFSDNPLLAKVEEYAAKEGAPVVALCAAI
ESEIAELEDADKAEFLETLGLEEPGLDRLIRAGYKLLGLQTYFTAGVKEVRAWTIHVGDTAPQAAGVIHTDFERGFIRAQ
TISFQDFVTLGGEAKAKEAGKMRAEGKDYVVQDGDVMNFLFNV

Sequences:

>Translated_363_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVEVPDHRLGELAKIINPQKIQPAIVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAIVNVVRCFDDPNIVHVAGKVDPIADIETILTELALADLSAVEKAIAREGKKAKAGDKDARA
LIAILEKLVPHLNEGKPARSLGLSDEDKALIKPLCLLTIKPAMYVANVAEDGFSDNPLLAKVEEYAAKEGAPVVALCAAI
ESEIAELEDADKAEFLETLGLEEPGLDRLIRAGYKLLGLQTYFTAGVKEVRAWTIHVGDTAPQAAGVIHTDFERGFIRAQ
TISFQDFVTLGGEAKAKEAGKMRAEGKDYVVQDGDVMNFLFNV
>Mature_362_residues
SLKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVEVPDHRLGELAKIINPQKIQPAIVEFVDIAGLVAGAS
KGEGLGNQFLANIRETDAIVNVVRCFDDPNIVHVAGKVDPIADIETILTELALADLSAVEKAIAREGKKAKAGDKDARAL
IAILEKLVPHLNEGKPARSLGLSDEDKALIKPLCLLTIKPAMYVANVAEDGFSDNPLLAKVEEYAAKEGAPVVALCAAIE
SEIAELEDADKAEFLETLGLEEPGLDRLIRAGYKLLGLQTYFTAGVKEVRAWTIHVGDTAPQAAGVIHTDFERGFIRAQT
ISFQDFVTLGGEAKAKEAGKMRAEGKDYVVQDGDVMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=43.360433604336, Blast_Score=288, Evalue=7e-78,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=37.6146788990826, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=71.0743801652893, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=29.9212598425197, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=41.2568306010929, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.2953929539295, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=35.2480417754569, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321649, Length=165, Percent_Identity=36.969696969697, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.9354838709677, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.9354838709677, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.9354838709677, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=39.6969696969697, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24585318, Length=140, Percent_Identity=34.2857142857143, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38771; Mature: 38640

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVEVPDHRLGELAKIINP
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCCC
QKIQPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVNVVRCFDDPNIVHVAGKVD
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIADIETILTELALADLSAVEKAIAREGKKAKAGDKDARALIAILEKLVPHLNEGKPARS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LGLSDEDKALIKPLCLLTIKPAMYVANVAEDGFSDNPLLAKVEEYAAKEGAPVVALCAAI
CCCCCCCHHHHHHHHHHEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
ESEIAELEDADKAEFLETLGLEEPGLDRLIRAGYKLLGLQTYFTAGVKEVRAWTIHVGDT
HHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECCC
APQAAGVIHTDFERGFIRAQTISFQDFVTLGGEAKAKEAGKMRAEGKDYVVQDGDVMNFL
CCCCCCCEEECHHCCEEEEEEECHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
FNV
HCC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVEVPDHRLGELAKIINP
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCCC
QKIQPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVNVVRCFDDPNIVHVAGKVD
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIADIETILTELALADLSAVEKAIAREGKKAKAGDKDARALIAILEKLVPHLNEGKPARS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LGLSDEDKALIKPLCLLTIKPAMYVANVAEDGFSDNPLLAKVEEYAAKEGAPVVALCAAI
CCCCCCCHHHHHHHHHHEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
ESEIAELEDADKAEFLETLGLEEPGLDRLIRAGYKLLGLQTYFTAGVKEVRAWTIHVGDT
HHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECCC
APQAAGVIHTDFERGFIRAQTISFQDFVTLGGEAKAKEAGKMRAEGKDYVVQDGDVMNFL
CCCCCCCEEECHHCCEEEEEEECHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]