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The map label for this gene is fpr [H]

Identifier: 34499500

GI number: 34499500

Start: 4376868

End: 4377659

Strand: Reverse

Name: fpr [H]

Synonym: CV_4045

Alternate gene names: 34499500

Gene position: 4377659-4376868 (Counterclockwise)

Preceding gene: 34499501

Following gene: 34499497

Centisome position: 92.14

GC content: 64.52

Gene sequence:

>792_bases
ATGGACGCCGCGCTAGAAGCCGAGATTCAACAGAAATACACCGTTGAAACCATCACCGACATGAAGCGCTGGACCGACAA
GTTGATCAGCTTCCGGCTGACGCGGCCCGCCGGTTTTCGCTTCGCGGCCGGCCAGTTCGCCCGGCTGGGCCTGCCGTTGG
AGAACGGCGGCCAGGCGTGGCGCGCGTATTCGATGTGCTCGGCCGAATACGACGAGTTCCTGGAGTTCTATTCCATCGTG
GTGCCGGAGGGCCAGTTCAGTTCCCGCCTCGCCAGGCTGCAGCCGGGGGCGGAGGTGATGCTGGACAAGCGGGCGATGGG
TTTTTTCCAGGCTGAGCGGCTGCCGGACGGCGAGGATCTGTGGCTGATCGCCACCGGCACCGGCATCGCGCCTTATCTGT
CGATTCTGAAACAACCCGAAGTGTGGCAACGCTTCGAGCGCATCGTGCTGGCGCACTGTGTCCGCGAGGCGGCGGAGCTG
TCGTTCCAGGACGAGATCGCCGCCTTGCGCGAGCATCCGCTGTGGCGTGAGCATGGCCGCAAGCTGCAGTACCTGCCTGT
GGTGACGCGTAATGCGCCCGAGGGCATGCTGAGCCAGCGCGTGCCGGCGCTGCTGCAGAGCGGCGAGTTGGCGGCGCGCG
CCGGCATCGAGATGTCGCCCGAGCACAGCCGCTTTATGCTGTGCGGCAATCCCAAAATGGTGGAGGATACCCACCGCCAA
CTGATGAAGATGGGCTACCGGATGACCCGGCAGAACGCGCCGGGCCATATCGTGCTGGAAAACGGCTGGTAA

Upstream 100 bases:

>100_bases
CGGGAACAAGCCTTGCATCCGCAGTTGGCGGACTGGCTTGGCAAGCAGGAAGAGGCGAGAGCATAATTGTTGAGTAAATT
ACTCAACAATTGGAGTGAAG

Downstream 100 bases:

>100_bases
AACTTAGCGGTTGGACGTGGCCAGCAGAGAGCCGAACACGAGGAAGCTGGCGCCGCTGGCCTTGTTGATCAGGTGGCCGC
CGCGCTCGTTGTCCAGCCAG

Product: ferredoxin-NADP reductase

Products: NA

Alternate protein names: FNR; DA1; Flavodoxin reductase; FLDR; FLXR; Methyl viologen resistance protein A [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDAALEAEIQQKYTVETITDMKRWTDKLISFRLTRPAGFRFAAGQFARLGLPLENGGQAWRAYSMCSAEYDEFLEFYSIV
VPEGQFSSRLARLQPGAEVMLDKRAMGFFQAERLPDGEDLWLIATGTGIAPYLSILKQPEVWQRFERIVLAHCVREAAEL
SFQDEIAALREHPLWREHGRKLQYLPVVTRNAPEGMLSQRVPALLQSGELAARAGIEMSPEHSRFMLCGNPKMVEDTHRQ
LMKMGYRMTRQNAPGHIVLENGW

Sequences:

>Translated_263_residues
MDAALEAEIQQKYTVETITDMKRWTDKLISFRLTRPAGFRFAAGQFARLGLPLENGGQAWRAYSMCSAEYDEFLEFYSIV
VPEGQFSSRLARLQPGAEVMLDKRAMGFFQAERLPDGEDLWLIATGTGIAPYLSILKQPEVWQRFERIVLAHCVREAAEL
SFQDEIAALREHPLWREHGRKLQYLPVVTRNAPEGMLSQRVPALLQSGELAARAGIEMSPEHSRFMLCGNPKMVEDTHRQ
LMKMGYRMTRQNAPGHIVLENGW
>Mature_263_residues
MDAALEAEIQQKYTVETITDMKRWTDKLISFRLTRPAGFRFAAGQFARLGLPLENGGQAWRAYSMCSAEYDEFLEFYSIV
VPEGQFSSRLARLQPGAEVMLDKRAMGFFQAERLPDGEDLWLIATGTGIAPYLSILKQPEVWQRFERIVLAHCVREAAEL
SFQDEIAALREHPLWREHGRKLQYLPVVTRNAPEGMLSQRVPALLQSGELAARAGIEMSPEHSRFMLCGNPKMVEDTHRQ
LMKMGYRMTRQNAPGHIVLENGW

Specific function: Transports electrons between flavodoxin or ferredoxin and NADPH. Involved in the reductive activation of cobalamin- independent methionine synthase, pyruvate formate lyase and anaerobic ribonucleotide reductase. Also protects against superoxide radicals d

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=248, Percent_Identity=42.741935483871, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 30017; Mature: 30017

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAALEAEIQQKYTVETITDMKRWTDKLISFRLTRPAGFRFAAGQFARLGLPLENGGQAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCHHHCCCCCCCCCCHH
RAYSMCSAEYDEFLEFYSIVVPEGQFSSRLARLQPGAEVMLDKRAMGFFQAERLPDGEDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCE
WLIATGTGIAPYLSILKQPEVWQRFERIVLAHCVREAAELSFQDEIAALREHPLWREHGR
EEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCC
KLQYLPVVTRNAPEGMLSQRVPALLQSGELAARAGIEMSPEHSRFMLCGNPKMVEDTHRQ
EEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
LMKMGYRMTRQNAPGHIVLENGW
HHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MDAALEAEIQQKYTVETITDMKRWTDKLISFRLTRPAGFRFAAGQFARLGLPLENGGQAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCHHHCCCCCCCCCCHH
RAYSMCSAEYDEFLEFYSIVVPEGQFSSRLARLQPGAEVMLDKRAMGFFQAERLPDGEDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCE
WLIATGTGIAPYLSILKQPEVWQRFERIVLAHCVREAAELSFQDEIAALREHPLWREHGR
EEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCC
KLQYLPVVTRNAPEGMLSQRVPALLQSGELAARAGIEMSPEHSRFMLCGNPKMVEDTHRQ
EEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
LMKMGYRMTRQNAPGHIVLENGW
HHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449868; 8346018; 9278503; 1400248; 2834327; 7961651; 9149148 [H]