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The map label for this gene is adi [H]

Identifier: 34499495

GI number: 34499495

Start: 4371548

End: 4373806

Strand: Direct

Name: adi [H]

Synonym: CV_4040

Alternate gene names: 34499495

Gene position: 4371548-4373806 (Clockwise)

Preceding gene: 34499494

Following gene: 34499498

Centisome position: 92.01

GC content: 65.07

Gene sequence:

>2259_bases
ATGCGTTTTCACTTCCCCATCGTGATCATCGACGAGGACTTCCGCTCGGAAAACACCAGCGGCTCCGGCATTCGCGAACT
GGCCGCCGCCATGGAGGCGGAAGGCATGAGCGTGATCGGCTACACCAGCTACGGCGACCTCACCTCCTTCGCCCAGCAGC
AAAGCCGCGCCGCCGGCTTCATCCTGTCGATAGACGACGAGGAATTCCAGACCGAGGACACGGCGCAAGAAGCGCTGGGC
AATCTGTACGGCTTCGTCGCCGAAATCCGCCGCCGCAACCCGGACATCCCGGTCTACCTGTACGGCGAGACCCGCACCGC
CCGCCACATCCCCAACGACATCCTGCGCGAGCTGCACGGCTTCATCCACATGCACGAGGACACGCCGGAGTTCGTCGCCC
GCCACATCATCCGCGAGGCCAAGAGCTATCTGGACAAGCTGGCGCCGCCGTTCTTCCGCGCGCTGGTGGACTACGCCTAC
GACGGCTCCTACTCCTGGCACTGCCCCGGCCACTCCGGCGGCGTCGCCTTCCTGAAGAGCCCGGTCGGCCAGATGTTCCA
CCAGTTCTTCGGCGAGAACATGCTGCGCGCCGACGTCTGCAACGCGGTGGACGAGCTGGGCCAGCTGCTGGACCACACCG
GCCCGGTGGCGGCGTCCGAGCGCAACGCGGCGCGCATCTTCAATGCCGACCACCTGTTCTTCGTCACCAACGGCACCTCC
ACCTCGAACAAGATCGTCTGGCACAGCTGCGTCGCCGCCGGCGACATCGTGCTGGTGGACCGCAACTGCCACAAGTCCAA
TCTGCACGCCATCATCATGACCGGGGCCATCCCGGTGTTCCTGATGCCGACGCGCAACCACTACGGCATCATCGGCCCGA
TCCCGAAGTCCGAGTTCCAGCCGGACAATATCAAGAAGAAGATCCTGGCCAATCCGTTCGCGCGCGAGATGCTGGAAAAG
CACCCCAACCGCAAGCCGCGCATCCTGACGCTGACCCAGTCCACCTACGACGGCATCCTGTACAACGTCGAGGAGATCAA
GGGCCTGCTGGACGGCGAGGTGGACACGCTGCACTTCGACGAAGCCTGGCTGCCGCACGCCTGCTTCCACGACTTCTACC
GCGACTTCCACGCCATCGGCGAAGGCCGGCCCCGCTGCGAGGACAGCCTGGTGTTCTCCACCCAGTCCACCCACAAGCTG
TTGGCCGGCATCAGCCAGGCCTCGCAGATCCTGGTGCAGGATCCGCAGAACCGGCAGCTCGACACCGCCTGGTTCAACGA
AGCCTACCTGATGCACACCTCGACCAGCCCGCAATACTCGATCATCGCCAGCTGCGACGTGGCCGCCGCGATGATGGAGC
AGCCGGGCGGCCAGTCGCTGGTGGAAGAATCGCTGGTGGAGGCGATGGAATTCCGCCGCGCGATGCGCAAGGTGGACGAG
GAATACGGCCGCGACTGGTGGTTCAGCGTATGGGGCCCGGACGATCTGTCCGACGACGGCATCTGCGACCAGACCGACTG
GACGCTGCGCCCCGACGAGCGCTGGCACGGCTTCGCCGGCATCGAGGACGGCTTCAACATGCTGGACCCGATCAAGGCCA
CCGTGCTGACGCCGGGCCTGGACGTGGACGGCAGCTTCGAGGAAATGGGCATCCCGGCCGCCATCGTCACCAAGTATCTG
ACCGAACACGGCGTGGTCGTCGAGAAAACCGGCCTGTACAGCTTCTTCATCATGTTCACCATCGGCATCACCAAGGGCCG
CTGGAACACGCTGATCTCGCTGCTGCAGCAGTTCAAGGACGATTTCGACAAGAACCAGCCGATGTGGCGCGTGATGCCGG
AATTCGTCGCCAAGCATCCGCAGTACGAGCGCGTCGGCCTGCAGGACCTGTGCCAGCGCATCCACGGCCTGTACGCCAAG
CACGACGTGGCGCGGCTGACCACCGACATCTACCTGTCCGACATGGAGCCGGCGATGCGCCCGGCCGACGCCTTCGCCAA
GATGGCGCACCGCGAGATCGAGCGCGTGCCGGTGGACCAGCTGGAAGGCCGCGTCACCGCGGTGCTGCTGACCCCCTACC
CGCCGGGCATCCCGCTGCTGATCCCGGGCGAGCGCTTCAACAAGACCATCGTCGACTACCTGCGCTTCGCCCAGGCCTTC
AACCGCGAGCTGCCGGGCTTCGAAACCGACGTCCACGGCCTGGTGGCGGTGGAGGTGCAGGACCGCAAGGTGTACTGCGT
GGACTGCGTCAAGCAATAA

Upstream 100 bases:

>100_bases
TCTGCGCCCCACGCGCACCTAGCGACATTGCCGCGGCAAAGTCCGGTGACGCACCGGCCCCGCTGCAGTGTCCGAGTTAA
CAGCAACAAGGACTCAAGGT

Downstream 100 bases:

>100_bases
GACGGGCAGCCGGAAACGACAAAGGCGGGAGCGATCCCGCCTTTTTTCATGCCCAAACGCCTTACAGCCGCACGCGCCAG
GTATTGCGCCCGCCGGCCTT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MRFHFPIVIIDEDFRSENTSGSGIRELAAAMEAEGMSVIGYTSYGDLTSFAQQQSRAAGFILSIDDEEFQTEDTAQEALG
NLYGFVAEIRRRNPDIPVYLYGETRTARHIPNDILRELHGFIHMHEDTPEFVARHIIREAKSYLDKLAPPFFRALVDYAY
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNADHLFFVTNGTS
TSNKIVWHSCVAAGDIVLVDRNCHKSNLHAIIMTGAIPVFLMPTRNHYGIIGPIPKSEFQPDNIKKKILANPFAREMLEK
HPNRKPRILTLTQSTYDGILYNVEEIKGLLDGEVDTLHFDEAWLPHACFHDFYRDFHAIGEGRPRCEDSLVFSTQSTHKL
LAGISQASQILVQDPQNRQLDTAWFNEAYLMHTSTSPQYSIIASCDVAAAMMEQPGGQSLVEESLVEAMEFRRAMRKVDE
EYGRDWWFSVWGPDDLSDDGICDQTDWTLRPDERWHGFAGIEDGFNMLDPIKATVLTPGLDVDGSFEEMGIPAAIVTKYL
TEHGVVVEKTGLYSFFIMFTIGITKGRWNTLISLLQQFKDDFDKNQPMWRVMPEFVAKHPQYERVGLQDLCQRIHGLYAK
HDVARLTTDIYLSDMEPAMRPADAFAKMAHREIERVPVDQLEGRVTAVLLTPYPPGIPLLIPGERFNKTIVDYLRFAQAF
NRELPGFETDVHGLVAVEVQDRKVYCVDCVKQ

Sequences:

>Translated_752_residues
MRFHFPIVIIDEDFRSENTSGSGIRELAAAMEAEGMSVIGYTSYGDLTSFAQQQSRAAGFILSIDDEEFQTEDTAQEALG
NLYGFVAEIRRRNPDIPVYLYGETRTARHIPNDILRELHGFIHMHEDTPEFVARHIIREAKSYLDKLAPPFFRALVDYAY
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNADHLFFVTNGTS
TSNKIVWHSCVAAGDIVLVDRNCHKSNLHAIIMTGAIPVFLMPTRNHYGIIGPIPKSEFQPDNIKKKILANPFAREMLEK
HPNRKPRILTLTQSTYDGILYNVEEIKGLLDGEVDTLHFDEAWLPHACFHDFYRDFHAIGEGRPRCEDSLVFSTQSTHKL
LAGISQASQILVQDPQNRQLDTAWFNEAYLMHTSTSPQYSIIASCDVAAAMMEQPGGQSLVEESLVEAMEFRRAMRKVDE
EYGRDWWFSVWGPDDLSDDGICDQTDWTLRPDERWHGFAGIEDGFNMLDPIKATVLTPGLDVDGSFEEMGIPAAIVTKYL
TEHGVVVEKTGLYSFFIMFTIGITKGRWNTLISLLQQFKDDFDKNQPMWRVMPEFVAKHPQYERVGLQDLCQRIHGLYAK
HDVARLTTDIYLSDMEPAMRPADAFAKMAHREIERVPVDQLEGRVTAVLLTPYPPGIPLLIPGERFNKTIVDYLRFAQAF
NRELPGFETDVHGLVAVEVQDRKVYCVDCVKQ
>Mature_752_residues
MRFHFPIVIIDEDFRSENTSGSGIRELAAAMEAEGMSVIGYTSYGDLTSFAQQQSRAAGFILSIDDEEFQTEDTAQEALG
NLYGFVAEIRRRNPDIPVYLYGETRTARHIPNDILRELHGFIHMHEDTPEFVARHIIREAKSYLDKLAPPFFRALVDYAY
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNADHLFFVTNGTS
TSNKIVWHSCVAAGDIVLVDRNCHKSNLHAIIMTGAIPVFLMPTRNHYGIIGPIPKSEFQPDNIKKKILANPFAREMLEK
HPNRKPRILTLTQSTYDGILYNVEEIKGLLDGEVDTLHFDEAWLPHACFHDFYRDFHAIGEGRPRCEDSLVFSTQSTHKL
LAGISQASQILVQDPQNRQLDTAWFNEAYLMHTSTSPQYSIIASCDVAAAMMEQPGGQSLVEESLVEAMEFRRAMRKVDE
EYGRDWWFSVWGPDDLSDDGICDQTDWTLRPDERWHGFAGIEDGFNMLDPIKATVLTPGLDVDGSFEEMGIPAAIVTKYL
TEHGVVVEKTGLYSFFIMFTIGITKGRWNTLISLLQQFKDDFDKNQPMWRVMPEFVAKHPQYERVGLQDLCQRIHGLYAK
HDVARLTTDIYLSDMEPAMRPADAFAKMAHREIERVPVDQLEGRVTAVLLTPYPPGIPLLIPGERFNKTIVDYLRFAQAF
NRELPGFETDVHGLVAVEVQDRKVYCVDCVKQ

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=769, Percent_Identity=37.3211963589077, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1790573, Length=714, Percent_Identity=39.3557422969188, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1786384, Length=714, Percent_Identity=39.3557422969188, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1786909, Length=680, Percent_Identity=33.3823529411765, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI87082193, Length=678, Percent_Identity=33.0383480825959, Blast_Score=345, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85144; Mature: 85144

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00018 EF_HAND_1 ; PS00703 OKR_DC_1 ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHFPIVIIDEDFRSENTSGSGIRELAAAMEAEGMSVIGYTSYGDLTSFAQQQSRAAGF
CEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCE
ILSIDDEEFQTEDTAQEALGNLYGFVAEIRRRNPDIPVYLYGETRTARHIPNDILRELHG
EEEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCHHHHHHHHH
FIHMHEDTPEFVARHIIREAKSYLDKLAPPFFRALVDYAYDGSYSWHCPGHSGGVAFLKS
HEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNADHLFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
TSNKIVWHSCVAAGDIVLVDRNCHKSNLHAIIMTGAIPVFLMPTRNHYGIIGPIPKSEFQ
CCCCEEEEHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCC
PDNIKKKILANPFAREMLEKHPNRKPRILTLTQSTYDGILYNVEEIKGLLDGEVDTLHFD
CCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHCCCCCEEECC
EAWLPHACFHDFYRDFHAIGEGRPRCEDSLVFSTQSTHKLLAGISQASQILVQDPQNRQL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHEEEECCCCCCC
DTAWFNEAYLMHTSTSPQYSIIASCDVAAAMMEQPGGQSLVEESLVEAMEFRRAMRKVDE
CHHHCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EYGRDWWFSVWGPDDLSDDGICDQTDWTLRPDERWHGFAGIEDGFNMLDPIKATVLTPGL
HHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHEECCCC
DVDGSFEEMGIPAAIVTKYLTEHGVVVEKTGLYSFFIMFTIGITKGRWNTLISLLQQFKD
CCCCCHHHHCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DFDKNQPMWRVMPEFVAKHPQYERVGLQDLCQRIHGLYAKHDVARLTTDIYLSDMEPAMR
HHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
PADAFAKMAHREIERVPVDQLEGRVTAVLLTPYPPGIPLLIPGERFNKTIVDYLRFAQAF
HHHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHH
NRELPGFETDVHGLVAVEVQDRKVYCVDCVKQ
CCCCCCCCCCCCEEEEEEEECCEEEEEECCCC
>Mature Secondary Structure
MRFHFPIVIIDEDFRSENTSGSGIRELAAAMEAEGMSVIGYTSYGDLTSFAQQQSRAAGF
CEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCE
ILSIDDEEFQTEDTAQEALGNLYGFVAEIRRRNPDIPVYLYGETRTARHIPNDILRELHG
EEEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCHHHHHHHHH
FIHMHEDTPEFVARHIIREAKSYLDKLAPPFFRALVDYAYDGSYSWHCPGHSGGVAFLKS
HEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNADHLFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
TSNKIVWHSCVAAGDIVLVDRNCHKSNLHAIIMTGAIPVFLMPTRNHYGIIGPIPKSEFQ
CCCCEEEEHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCC
PDNIKKKILANPFAREMLEKHPNRKPRILTLTQSTYDGILYNVEEIKGLLDGEVDTLHFD
CCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHCCCCCEEECC
EAWLPHACFHDFYRDFHAIGEGRPRCEDSLVFSTQSTHKLLAGISQASQILVQDPQNRQL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHEEEECCCCCCC
DTAWFNEAYLMHTSTSPQYSIIASCDVAAAMMEQPGGQSLVEESLVEAMEFRRAMRKVDE
CHHHCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EYGRDWWFSVWGPDDLSDDGICDQTDWTLRPDERWHGFAGIEDGFNMLDPIKATVLTPGL
HHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHEECCCC
DVDGSFEEMGIPAAIVTKYLTEHGVVVEKTGLYSFFIMFTIGITKGRWNTLISLLQQFKD
CCCCCHHHHCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DFDKNQPMWRVMPEFVAKHPQYERVGLQDLCQRIHGLYAKHDVARLTTDIYLSDMEPAMR
HHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
PADAFAKMAHREIERVPVDQLEGRVTAVLLTPYPPGIPLLIPGERFNKTIVDYLRFAQAF
HHHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHH
NRELPGFETDVHGLVAVEVQDRKVYCVDCVKQ
CCCCCCCCCCCCEEEEEEEECCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]