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The map label for this gene is mpg1 [H]

Identifier: 34499485

GI number: 34499485

Start: 4356660

End: 4357706

Strand: Reverse

Name: mpg1 [H]

Synonym: CV_4030

Alternate gene names: 34499485

Gene position: 4357706-4356660 (Counterclockwise)

Preceding gene: 34499486

Following gene: 34499484

Centisome position: 91.72

GC content: 51.67

Gene sequence:

>1047_bases
ATGGCGCATGATTGGGAAAAGGTACTGCTGTCTCCTGATACGCCTGCTGAATCAGCGTTGAGAGTGCTGGATGACAGTGG
CTTGCGATTGGTGCTGGTTGTTGATGAGCAGCGACGCCTACTTGGCACCCTGACGGATGGAGACGTGCGCAGGGCGTTGC
TTCGCCATGTCAATTTCATGACCGCCGCCGTTGCGGACATCATGCACCGCGAGCCCCGGGTCGCGCTCGCCAGCGCTAGC
CGCGAACAATTGCGTCACCTGATGGAACAGCATTCCCTGTTGCATATCCCTTTGCTGGATCACGATGATCGAGTGGTTGG
CCTGGAAACCTACCAGGAGGTTCTGCAGCGCCCGCGCCGCGACAATTGGGTATTTTTGATGGCTGGTGGTTTCGGAAAAC
GCTTACGGCCATTGACTGACAACTGCCCGAAACCGATGTTGCTGGTGGGTGGCAAACCGATGTTGCAAACCATATTGGAA
GGCTTCATCGCTGCGGGCTTCCACCGGTTTTATATTTCCGTTCATTATCTGCCGGAAACTATCAAGAACTATTTTGGCGA
TGGCTCTAAATGGGGTGTAACGATAGTTTATATCGAAGAGGATCAGCCTTTGGGGACAGGCGGCGCATTGGGTTTGTTGC
CTGGGACGGATGATTTGCCAATCATCATGATGAATGGCGATATTTTGACCCGCCTCGATTTTAATGCCTTGCTCGATTTT
CATGAAAAGCATGCGGCGGATTTGACGCTCTGCGTACGCGAGTACGATGTGCAAATCCCGTTTGGCGTTGTGGAAGGCAA
CGATGTGACGGTCACATCCATTGTCGAGAAGCCAAAGCATCGCTTTTTTGTCAATGCTGGTATCTATGTTGTTACGCCGC
AAGCAATTGCACGTGTATTACCATCCATGCGCGTAGACATGCCTGATTTGATTAAACAGATCATTGCAGATCAGCGCAAT
GTCTCGATGTTCCCGATCCGCGAATATTGGCTGGATATCGGAAGGCCAGAAGATTTCGATGTGGCTCAAACGAGTATTGC
CCAATGA

Upstream 100 bases:

>100_bases
GCGATGGCGTGTCGCCGTATCGTTTCTGGGATTTCATCGGTAAACCAGCCACCAGGGATTATCGCGCCGACGAAAAACTG
GACGCCGGATTGGAGTAATC

Downstream 100 bases:

>100_bases
TGAAGCTGCTTTCCTTTGATGAAGCTTGCCAATGGTTCGACTCTCTGCCGGCACATAAAAGAATTGCAACGTTATCGCCT
TATTATGTTCTTTTAGATGC

Product: sugar-phosphate nucleotide transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MAHDWEKVLLSPDTPAESALRVLDDSGLRLVLVVDEQRRLLGTLTDGDVRRALLRHVNFMTAAVADIMHREPRVALASAS
REQLRHLMEQHSLLHIPLLDHDDRVVGLETYQEVLQRPRRDNWVFLMAGGFGKRLRPLTDNCPKPMLLVGGKPMLQTILE
GFIAAGFHRFYISVHYLPETIKNYFGDGSKWGVTIVYIEEDQPLGTGGALGLLPGTDDLPIIMMNGDILTRLDFNALLDF
HEKHAADLTLCVREYDVQIPFGVVEGNDVTVTSIVEKPKHRFFVNAGIYVVTPQAIARVLPSMRVDMPDLIKQIIADQRN
VSMFPIREYWLDIGRPEDFDVAQTSIAQ

Sequences:

>Translated_348_residues
MAHDWEKVLLSPDTPAESALRVLDDSGLRLVLVVDEQRRLLGTLTDGDVRRALLRHVNFMTAAVADIMHREPRVALASAS
REQLRHLMEQHSLLHIPLLDHDDRVVGLETYQEVLQRPRRDNWVFLMAGGFGKRLRPLTDNCPKPMLLVGGKPMLQTILE
GFIAAGFHRFYISVHYLPETIKNYFGDGSKWGVTIVYIEEDQPLGTGGALGLLPGTDDLPIIMMNGDILTRLDFNALLDF
HEKHAADLTLCVREYDVQIPFGVVEGNDVTVTSIVEKPKHRFFVNAGIYVVTPQAIARVLPSMRVDMPDLIKQIIADQRN
VSMFPIREYWLDIGRPEDFDVAQTSIAQ
>Mature_347_residues
AHDWEKVLLSPDTPAESALRVLDDSGLRLVLVVDEQRRLLGTLTDGDVRRALLRHVNFMTAAVADIMHREPRVALASASR
EQLRHLMEQHSLLHIPLLDHDDRVVGLETYQEVLQRPRRDNWVFLMAGGFGKRLRPLTDNCPKPMLLVGGKPMLQTILEG
FIAAGFHRFYISVHYLPETIKNYFGDGSKWGVTIVYIEEDQPLGTGGALGLLPGTDDLPIIMMNGDILTRLDFNALLDFH
EKHAADLTLCVREYDVQIPFGVVEGNDVTVTSIVEKPKHRFFVNAGIYVVTPQAIARVLPSMRVDMPDLIKQIIADQRNV
SMFPIREYWLDIGRPEDFDVAQTSIAQ

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=30.9734513274336, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI11761619, Length=226, Percent_Identity=30.9734513274336, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI133931050, Length=224, Percent_Identity=29.0178571428571, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320148, Length=231, Percent_Identity=32.034632034632, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21355443, Length=225, Percent_Identity=29.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644084, Length=225, Percent_Identity=29.3333333333333, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39278; Mature: 39147

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDWEKVLLSPDTPAESALRVLDDSGLRLVLVVDEQRRLLGTLTDGDVRRALLRHVNFM
CCCCCHHEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHH
TAAVADIMHREPRVALASASREQLRHLMEQHSLLHIPLLDHDDRVVGLETYQEVLQRPRR
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCEECHHHHHHHHHCCCC
DNWVFLMAGGFGKRLRPLTDNCPKPMLLVGGKPMLQTILEGFIAAGFHRFYISVHYLPET
CCEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCEEEEEEEEEECHHH
IKNYFGDGSKWGVTIVYIEEDQPLGTGGALGLLPGTDDLPIIMMNGDILTRLDFNALLDF
HHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCEEEEECHHHHHHH
HEKHAADLTLCVREYDVQIPFGVVEGNDVTVTSIVEKPKHRFFVNAGIYVVTPQAIARVL
HHHHHCHHEEEEEHHCEECCEEEECCCCEEEEHHHHCCCCEEEEECCEEEECHHHHHHHH
PSMRVDMPDLIKQIIADQRNVSMFPIREYWLDIGRPEDFDVAQTSIAQ
HHCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
AHDWEKVLLSPDTPAESALRVLDDSGLRLVLVVDEQRRLLGTLTDGDVRRALLRHVNFM
CCCCHHEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHH
TAAVADIMHREPRVALASASREQLRHLMEQHSLLHIPLLDHDDRVVGLETYQEVLQRPRR
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCEECHHHHHHHHHCCCC
DNWVFLMAGGFGKRLRPLTDNCPKPMLLVGGKPMLQTILEGFIAAGFHRFYISVHYLPET
CCEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCEEEEEEEEEECHHH
IKNYFGDGSKWGVTIVYIEEDQPLGTGGALGLLPGTDDLPIIMMNGDILTRLDFNALLDF
HHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCEEEEECHHHHHHH
HEKHAADLTLCVREYDVQIPFGVVEGNDVTVTSIVEKPKHRFFVNAGIYVVTPQAIARVL
HHHHHCHHEEEEEHHCEECCEEEECCCCEEEEHHHHCCCCEEEEECCEEEECHHHHHHHH
PSMRVDMPDLIKQIIADQRNVSMFPIREYWLDIGRPEDFDVAQTSIAQ
HHCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]