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The map label for this gene is cyoB [H]

Identifier: 34499450

GI number: 34499450

Start: 4321980

End: 4324022

Strand: Reverse

Name: cyoB [H]

Synonym: CV_3995

Alternate gene names: 34499450

Gene position: 4324022-4321980 (Counterclockwise)

Preceding gene: 34499451

Following gene: 34499449

Centisome position: 91.01

GC content: 62.9

Gene sequence:

>2043_bases
ATGTTGTTAGGTAAACTGACTCTGGACGCGATCCCGTTCCACGAGCCCATCATCATGGGGGCGCTGGGCGGCGCCGGCCT
GATCGGGCTGATGGTGTTCGCGTTGATCACCAAGTTCGGCAAGTGGGGCTATCTCTGGAAAGAATGGCTCACTTCCGTGG
ATCACAAGAAAATCGGCGTGATGTACATCATCGTCGCGATGATCATGCTGCTGCGCGGCTTCGCCGACGCGCTGATGATG
CGCACCCAGCTGGCGATGGCCACCGGCGGCGCCCACGGCGTGTTCCCGCCCGAGCACTATGACCAGATCTTCACCGCCCA
CGGCGTGATCATGATCATCTTCATGGCGATGCCGTTCATGACGGGCCTGATGAACATCGTGGTGCCGCTGCAGATCGGCG
CGCGCGACGTGGCTTTCCCCTTCCTGAACTCGCTGAGCTTCTGGCTGCTGGTGTCCGCGGTGATCCTGGTCAACCTGTCG
CTGGGCGTGGGCAACTTTGCCCGCACCGGCTGGGTGGCCTATCCGCCGCTGGCCGAGCTGGGATTCAGCCCTGACGTGGG
GGTGGATTACTACATCTGGGCCTTGCAGATATCAGGCATCGGGACGACGCTGACCGCGATCAACTTCCTGGTGACCGTGA
TCAAGATGCGCGCCCCGGGCATGAAGCTGATGGACATGCCGATCTTCACCTGGACCTGCACCTGGGCCAACGTGCTGATC
GCCACCTCCTTCCCGATCCTGACCGGCGCGCTGGCCATGCTGGCGCTGGACCGCTACCTGGACTTCCACTTCTTCACCGC
GGAACTGGGCGGCAACGCCATGATGTACCTGAACCTGTTCTGGGCCTGGGGCCACCCCGAGGTGTACATCCTGGTTCTGC
CGGCGTTCGGCATCTTCTCGGAAGTGGTGTCCACTTTCGCCGGCAAGCGCCTGTTCGGCCACAAGTCCATGATCTACGCC
AGCGGCGCGATCTCGGTGCTGGGCTTCATGGTATGGCTGCACCACTTCTTCACGATGGGCTCCGGCGCCAACGTCAACGC
CTTCTTCGGCATCGCGACCATGATCATCTCGATCCCGACCGGCGTGAAGCTGTTCAACTGGCTGTTCACCATCTACAAGG
GCCGCCTGCGCTTTGAAACCCCGATTCTGTGGACCCTGGGCTTCATGGTGACCTTCTCCATCGGCGGCATGACCGGCGTG
CTGTTGGCCGTGCCGGGCGCAGACTACGTGCTGCACAACAGCCTGTTCCTGATCGCCCACTTCCACAACACCATCATCGG
CGGCGCCGTGTTCGGCTACCTGGCCGGCGTGTCGTTCTGGTTCCCGAAGGTGTTCGGCTTCAAGCTGAACGACAAGCTGG
GCAAGGCCTCGTTCTGGTTCTGGCAGATCGGCTTCATGTTCGCCTTCATGCCGCTGTACGTGCTGGGCTTCCTGGGCATG
ACCCGCCGCCTGAACCACACCGACAATCCGGCCTGGGAGCCGTGGCTGTACATCGCCCTGTTCGGCGCGCTGCTGATCGC
CGCCGGCATCGCCTGCCAGCTGCTGCAGATCGTGGTGAGCATCCGCGACCGCAAGAAGCTGGTGGACGAAACCGGCGACC
CGTGGAACGGCCACACCCTGGAATGGTCCACGTCTTCCCCGGCGCCGTTCTACAACTTCGCCAAGCTGCCGCAGGTGCAT
GACATCGACGCCTTCACCGACATGAAGGAAAAGGGCGTCGCCTACGCCGTGCCGAAGTCGTACGAGCCGATCCACATGCC
GCGCAACACCGCGGTGGGCGTTTACATCGGCGCCTTCACCACGGTGCTGGGCTTCGCGCTGATCTGGCACATCTGGTGGC
TGGCCATCGTCGGCCTGGTGGGCATCGTCGGCTGCATGCTGGCGCGCGCCTACGACAACGACCTGGACTACTACGTGCAG
CCGGACGAAGTGGAGGCGATCGAACGCGCCCGCTTCGAGAAGCTGGGCATCGACGTCGACAACTACACCGAGCGTGATCC
GGCCCAGCCGAAAAAGGCTGCGCGTCCGACCACTACCGCGTAA

Upstream 100 bases:

>100_bases
TCCGTCGCTGGCTGAAAGCGACGACGCCATCAAGCTGACCAAGCTGACCAAAGAACTGTGCGCAGCCATCACCCCGCCGG
TTGTCAAGGAGTAAGCATCG

Downstream 100 bases:

>100_bases
GGGGTTGAACCTGACATGACGACTTATGTAAAAGAAGCGCACGCCGCGCACGACGACCACGAGCACCACGACAGCGGTTC
GCAAACCGTGCTGGGCTTCT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MLLGKLTLDAIPFHEPIIMGALGGAGLIGLMVFALITKFGKWGYLWKEWLTSVDHKKIGVMYIIVAMIMLLRGFADALMM
RTQLAMATGGAHGVFPPEHYDQIFTAHGVIMIIFMAMPFMTGLMNIVVPLQIGARDVAFPFLNSLSFWLLVSAVILVNLS
LGVGNFARTGWVAYPPLAELGFSPDVGVDYYIWALQISGIGTTLTAINFLVTVIKMRAPGMKLMDMPIFTWTCTWANVLI
ATSFPILTGALAMLALDRYLDFHFFTAELGGNAMMYLNLFWAWGHPEVYILVLPAFGIFSEVVSTFAGKRLFGHKSMIYA
SGAISVLGFMVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKLFNWLFTIYKGRLRFETPILWTLGFMVTFSIGGMTGV
LLAVPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGVSFWFPKVFGFKLNDKLGKASFWFWQIGFMFAFMPLYVLGFLGM
TRRLNHTDNPAWEPWLYIALFGALLIAAGIACQLLQIVVSIRDRKKLVDETGDPWNGHTLEWSTSSPAPFYNFAKLPQVH
DIDAFTDMKEKGVAYAVPKSYEPIHMPRNTAVGVYIGAFTTVLGFALIWHIWWLAIVGLVGIVGCMLARAYDNDLDYYVQ
PDEVEAIERARFEKLGIDVDNYTERDPAQPKKAARPTTTA

Sequences:

>Translated_680_residues
MLLGKLTLDAIPFHEPIIMGALGGAGLIGLMVFALITKFGKWGYLWKEWLTSVDHKKIGVMYIIVAMIMLLRGFADALMM
RTQLAMATGGAHGVFPPEHYDQIFTAHGVIMIIFMAMPFMTGLMNIVVPLQIGARDVAFPFLNSLSFWLLVSAVILVNLS
LGVGNFARTGWVAYPPLAELGFSPDVGVDYYIWALQISGIGTTLTAINFLVTVIKMRAPGMKLMDMPIFTWTCTWANVLI
ATSFPILTGALAMLALDRYLDFHFFTAELGGNAMMYLNLFWAWGHPEVYILVLPAFGIFSEVVSTFAGKRLFGHKSMIYA
SGAISVLGFMVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKLFNWLFTIYKGRLRFETPILWTLGFMVTFSIGGMTGV
LLAVPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGVSFWFPKVFGFKLNDKLGKASFWFWQIGFMFAFMPLYVLGFLGM
TRRLNHTDNPAWEPWLYIALFGALLIAAGIACQLLQIVVSIRDRKKLVDETGDPWNGHTLEWSTSSPAPFYNFAKLPQVH
DIDAFTDMKEKGVAYAVPKSYEPIHMPRNTAVGVYIGAFTTVLGFALIWHIWWLAIVGLVGIVGCMLARAYDNDLDYYVQ
PDEVEAIERARFEKLGIDVDNYTERDPAQPKKAARPTTTA
>Mature_680_residues
MLLGKLTLDAIPFHEPIIMGALGGAGLIGLMVFALITKFGKWGYLWKEWLTSVDHKKIGVMYIIVAMIMLLRGFADALMM
RTQLAMATGGAHGVFPPEHYDQIFTAHGVIMIIFMAMPFMTGLMNIVVPLQIGARDVAFPFLNSLSFWLLVSAVILVNLS
LGVGNFARTGWVAYPPLAELGFSPDVGVDYYIWALQISGIGTTLTAINFLVTVIKMRAPGMKLMDMPIFTWTCTWANVLI
ATSFPILTGALAMLALDRYLDFHFFTAELGGNAMMYLNLFWAWGHPEVYILVLPAFGIFSEVVSTFAGKRLFGHKSMIYA
SGAISVLGFMVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKLFNWLFTIYKGRLRFETPILWTLGFMVTFSIGGMTGV
LLAVPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGVSFWFPKVFGFKLNDKLGKASFWFWQIGFMFAFMPLYVLGFLGM
TRRLNHTDNPAWEPWLYIALFGALLIAAGIACQLLQIVVSIRDRKKLVDETGDPWNGHTLEWSTSSPAPFYNFAKLPQVH
DIDAFTDMKEKGVAYAVPKSYEPIHMPRNTAVGVYIGAFTTVLGFALIWHIWWLAIVGLVGIVGCMLARAYDNDLDYYVQ
PDEVEAIERARFEKLGIDVDNYTERDPAQPKKAARPTTTA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=38.5964912280702, Blast_Score=327, Evalue=2e-89,
Organism=Escherichia coli, GI1786634, Length=654, Percent_Identity=66.5137614678899, Blast_Score=919, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=461, Percent_Identity=40.1301518438178, Blast_Score=337, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=41.4860681114551, Blast_Score=243, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=34.8, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 75612; Mature: 75612

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGKLTLDAIPFHEPIIMGALGGAGLIGLMVFALITKFGKWGYLWKEWLTSVDHKKIGV
CCCCCEEECCCCCCCCHHEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
MYIIVAMIMLLRGFADALMMRTQLAMATGGAHGVFPPEHYDQIFTAHGVIMIIFMAMPFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGLMNIVVPLQIGARDVAFPFLNSLSFWLLVSAVILVNLSLGVGNFARTGWVAYPPLAEL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEECCCHHHC
GFSPDVGVDYYIWALQISGIGTTLTAINFLVTVIKMRAPGMKLMDMPIFTWTCTWANVLI
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEHHHHHHHH
ATSFPILTGALAMLALDRYLDFHFFTAELGGNAMMYLNLFWAWGHPEVYILVLPAFGIFS
HHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEEECCCCEEEEEEECHHHHHH
EVVSTFAGKRLFGHKSMIYASGAISVLGFMVWLHHFFTMGSGANVNAFFGIATMIISIPT
HHHHHHHCCHHHCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GVKLFNWLFTIYKGRLRFETPILWTLGFMVTFSIGGMTGVLLAVPGADYVLHNSLFLIAH
HHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHCCEEEEEE
FHNTIIGGAVFGYLAGVSFWFPKVFGFKLNDKLGKASFWFWQIGFMFAFMPLYVLGFLGM
HHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRRLNHTDNPAWEPWLYIALFGALLIAAGIACQLLQIVVSIRDRKKLVDETGDPWNGHTL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EWSTSSPAPFYNFAKLPQVHDIDAFTDMKEKGVAYAVPKSYEPIHMPRNTAVGVYIGAFT
EECCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEHHHHHH
TVLGFALIWHIWWLAIVGLVGIVGCMLARAYDNDLDYYVQPDEVEAIERARFEKLGIDVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCC
NYTERDPAQPKKAARPTTTA
CCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MLLGKLTLDAIPFHEPIIMGALGGAGLIGLMVFALITKFGKWGYLWKEWLTSVDHKKIGV
CCCCCEEECCCCCCCCHHEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
MYIIVAMIMLLRGFADALMMRTQLAMATGGAHGVFPPEHYDQIFTAHGVIMIIFMAMPFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGLMNIVVPLQIGARDVAFPFLNSLSFWLLVSAVILVNLSLGVGNFARTGWVAYPPLAEL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEECCCHHHC
GFSPDVGVDYYIWALQISGIGTTLTAINFLVTVIKMRAPGMKLMDMPIFTWTCTWANVLI
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEHHHHHHHH
ATSFPILTGALAMLALDRYLDFHFFTAELGGNAMMYLNLFWAWGHPEVYILVLPAFGIFS
HHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEEECCCCEEEEEEECHHHHHH
EVVSTFAGKRLFGHKSMIYASGAISVLGFMVWLHHFFTMGSGANVNAFFGIATMIISIPT
HHHHHHHCCHHHCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GVKLFNWLFTIYKGRLRFETPILWTLGFMVTFSIGGMTGVLLAVPGADYVLHNSLFLIAH
HHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHCCEEEEEE
FHNTIIGGAVFGYLAGVSFWFPKVFGFKLNDKLGKASFWFWQIGFMFAFMPLYVLGFLGM
HHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRRLNHTDNPAWEPWLYIALFGALLIAAGIACQLLQIVVSIRDRKKLVDETGDPWNGHTL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EWSTSSPAPFYNFAKLPQVHDIDAFTDMKEKGVAYAVPKSYEPIHMPRNTAVGVYIGAFT
EECCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEHHHHHH
TVLGFALIWHIWWLAIVGLVGIVGCMLARAYDNDLDYYVQPDEVEAIERARFEKLGIDVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCC
NYTERDPAQPKKAARPTTTA
CCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]