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The map label for this gene is arpC [H]

Identifier: 34499293

GI number: 34499293

Start: 4140532

End: 4141962

Strand: Direct

Name: arpC [H]

Synonym: CV_3838

Alternate gene names: 34499293

Gene position: 4140532-4141962 (Clockwise)

Preceding gene: 34499292

Following gene: 34499294

Centisome position: 87.15

GC content: 72.96

Gene sequence:

>1431_bases
ATGCGCGCGCTTCCCCTGCTGCTCGCCGCCGCGCTGTCCGGCTGCGCCGCCGTCGGCCCCGACTACCGCCCCCCGGCCAG
CGAATTGCCGGCGCAGTGGAAGAGCGACGCCGGCTGGCTGCCGGCTGCGCCCGCCGATGCGCTGCCCAAACGCGACTGGT
GGCGGATGTTCGGCGACGAGGGTCTGAACCGCCTGGAAGCCGACGCGCTGGCCCGCAGCCCGACGCTGCAGCTGGCGCTG
GCCAGGCTGGACCAGGCCCAGGCGCAAAGCCGCATCCGCGGCGCCGCCGCGCTGCCCGCCGCCAGCCTGGGCGCGGCGGC
CTCGCGCAGCCGCGTCTCCGCCGACCGCCCCTTGTCCAGCTATGGCGCCAGCAACGCCAGCGCGGTGCAGAGCGATCTGA
AGCCCATGCTCAGCGTCAGCTACGAGATCGACTGGCTGGGCCGGGTGCGGCGCGACATCGAAAGCGCGCGCGCCGGCGCC
GAACAGGCCGCCTCCGATCGCGCCAACGTCGAACTACTGCTGACCGCCCAGCTGGCCAGCGCCTATCTGCAACTGCGCCA
AGAGGACGAAGAAATCCGGCTGCTGGACGGCATCCTGGACGCGCAGCAGCGGGTGCTGGAGCTGACCCGCATCCGCCACC
TGGCCGGCCTCGCGTCCGCCGGCGACGAAGCGCAGCAGGCCGCCGCCTCCGCCGCCAGCCGCGCCCAGCGCGAACTGCTG
CTCAACCAGCGCCGCGCCAATGAGGATCTGCTGGCCACACTCAGCGGCGCGCCGGCGCCCTCGTTCCGGCTGGCATCCGG
CTCGCTGCCCGCCGCCTTGCCGGCTTTGCCGAACGGCGCGCCCAGCGATCTGCTGCAGCGCCGCCCCGACATCGCCTCGG
CCGAACGGGCGATGGCCGCCGCCAACGCCCAGATCGGCGTCGCCAAGGCCGCGTATTTCCCTCAACTGACGCTGGCGCCG
ACCTATCTTGGCAGCGAATCGACCGGCCTCGGCAAGCTGTTCTCCACGCCGGCGCTGATCTGGGGCGTGGGCCTGCAGGC
GACGCAAACGCTGTTCGACAACGGCAAGGCCCGCGCCGGCGTCGATTACGCCGCAGCCGGCTACCGCGCCGCGCTGGCCG
CCTATCGCCAGACTGTGCTGCAAGCGCTGCAAGAAGCCCAGGACGCGCTGGGCTCGCTGCACGGGCTGGACCAGGCGCGC
CGCCAGCAGGACGAGGCGGCGCGCAACCAGGACAAGGCCTACGCCGTCATCCAGTTGCGCTATCGCGAAGGCCTGGACAG
CGCGCTGACGCTGGCTTCCGCCCGCCAAAGCCAGCTGGCGGCGCAACGGACGCTGGCGCAGCTGCGCGGCGCCCAGCTGG
CCGCCAGCGTCAGCTTGCTGAAGGCGCTGGGCGGCGGCTGGCAAGCGCCATTCCCTCGCCAACCGTTTTAA

Upstream 100 bases:

>100_bases
GGCCTGAAGCCGGACGACAAGGTGATCGTCAACCCGCCGGACTCGATCAACGATGGACAAGCGGTGACCGTGGTGCCCGC
CGCCAAGGGGGAGTGAGGCG

Downstream 100 bases:

>100_bases
TGGACACATCTCCAAATCGTAATAAAACTGCTACAAATAACTGGACGGGCCGGCGGGATGCCCCGCCGCCTGCCGGTTAG
CCGCAGCGGCCTGGCCCATT

Product: outer membrane drug efflux lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MRALPLLLAAALSGCAAVGPDYRPPASELPAQWKSDAGWLPAAPADALPKRDWWRMFGDEGLNRLEADALARSPTLQLAL
ARLDQAQAQSRIRGAAALPAASLGAAASRSRVSADRPLSSYGASNASAVQSDLKPMLSVSYEIDWLGRVRRDIESARAGA
EQAASDRANVELLLTAQLASAYLQLRQEDEEIRLLDGILDAQQRVLELTRIRHLAGLASAGDEAQQAAASAASRAQRELL
LNQRRANEDLLATLSGAPAPSFRLASGSLPAALPALPNGAPSDLLQRRPDIASAERAMAAANAQIGVAKAAYFPQLTLAP
TYLGSESTGLGKLFSTPALIWGVGLQATQTLFDNGKARAGVDYAAAGYRAALAAYRQTVLQALQEAQDALGSLHGLDQAR
RQQDEAARNQDKAYAVIQLRYREGLDSALTLASARQSQLAAQRTLAQLRGAQLAASVSLLKALGGGWQAPFPRQPF

Sequences:

>Translated_476_residues
MRALPLLLAAALSGCAAVGPDYRPPASELPAQWKSDAGWLPAAPADALPKRDWWRMFGDEGLNRLEADALARSPTLQLAL
ARLDQAQAQSRIRGAAALPAASLGAAASRSRVSADRPLSSYGASNASAVQSDLKPMLSVSYEIDWLGRVRRDIESARAGA
EQAASDRANVELLLTAQLASAYLQLRQEDEEIRLLDGILDAQQRVLELTRIRHLAGLASAGDEAQQAAASAASRAQRELL
LNQRRANEDLLATLSGAPAPSFRLASGSLPAALPALPNGAPSDLLQRRPDIASAERAMAAANAQIGVAKAAYFPQLTLAP
TYLGSESTGLGKLFSTPALIWGVGLQATQTLFDNGKARAGVDYAAAGYRAALAAYRQTVLQALQEAQDALGSLHGLDQAR
RQQDEAARNQDKAYAVIQLRYREGLDSALTLASARQSQLAAQRTLAQLRGAQLAASVSLLKALGGGWQAPFPRQPF
>Mature_476_residues
MRALPLLLAAALSGCAAVGPDYRPPASELPAQWKSDAGWLPAAPADALPKRDWWRMFGDEGLNRLEADALARSPTLQLAL
ARLDQAQAQSRIRGAAALPAASLGAAASRSRVSADRPLSSYGASNASAVQSDLKPMLSVSYEIDWLGRVRRDIESARAGA
EQAASDRANVELLLTAQLASAYLQLRQEDEEIRLLDGILDAQQRVLELTRIRHLAGLASAGDEAQQAAASAASRAQRELL
LNQRRANEDLLATLSGAPAPSFRLASGSLPAALPALPNGAPSDLLQRRPDIASAERAMAAANAQIGVAKAAYFPQLTLAP
TYLGSESTGLGKLFSTPALIWGVGLQATQTLFDNGKARAGVDYAAAGYRAALAAYRQTVLQALQEAQDALGSLHGLDQAR
RQQDEAARNQDKAYAVIQLRYREGLDSALTLASARQSQLAAQRTLAQLRGAQLAASVSLLKALGGGWQAPFPRQPF

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=472, Percent_Identity=28.1779661016949, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI2367348, Length=489, Percent_Identity=28.4253578732106, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50342; Mature: 50342

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALPLLLAAALSGCAAVGPDYRPPASELPAQWKSDAGWLPAAPADALPKRDWWRMFGDE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
GLNRLEADALARSPTLQLALARLDQAQAQSRIRGAAALPAASLGAAASRSRVSADRPLSS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHH
YGASNASAVQSDLKPMLSVSYEIDWLGRVRRDIESARAGAEQAASDRANVELLLTAQLAS
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEHHHHHH
AYLQLRQEDEEIRLLDGILDAQQRVLELTRIRHLAGLASAGDEAQQAAASAASRAQRELL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LNQRRANEDLLATLSGAPAPSFRLASGSLPAALPALPNGAPSDLLQRRPDIASAERAMAA
HHHHCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
ANAQIGVAKAAYFPQLTLAPTYLGSESTGLGKLFSTPALIWGVGLQATQTLFDNGKARAG
HCCCHHHHHHHHCCCCEECHHHCCCCCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCCCC
VDYAAAGYRAALAAYRQTVLQALQEAQDALGSLHGLDQARRQQDEAARNQDKAYAVIQLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
YREGLDSALTLASARQSQLAAQRTLAQLRGAQLAASVSLLKALGGGWQAPFPRQPF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRALPLLLAAALSGCAAVGPDYRPPASELPAQWKSDAGWLPAAPADALPKRDWWRMFGDE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
GLNRLEADALARSPTLQLALARLDQAQAQSRIRGAAALPAASLGAAASRSRVSADRPLSS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHH
YGASNASAVQSDLKPMLSVSYEIDWLGRVRRDIESARAGAEQAASDRANVELLLTAQLAS
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEHHHHHH
AYLQLRQEDEEIRLLDGILDAQQRVLELTRIRHLAGLASAGDEAQQAAASAASRAQRELL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LNQRRANEDLLATLSGAPAPSFRLASGSLPAALPALPNGAPSDLLQRRPDIASAERAMAA
HHHHCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
ANAQIGVAKAAYFPQLTLAPTYLGSESTGLGKLFSTPALIWGVGLQATQTLFDNGKARAG
HCCCHHHHHHHHCCCCEECHHHCCCCCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCCCC
VDYAAAGYRAALAAYRQTVLQALQEAQDALGSLHGLDQARRQQDEAARNQDKAYAVIQLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
YREGLDSALTLASARQSQLAAQRTLAQLRGAQLAASVSLLKALGGGWQAPFPRQPF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]