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The map label for this gene is mdtA [H]

Identifier: 34499292

GI number: 34499292

Start: 4139367

End: 4140527

Strand: Direct

Name: mdtA [H]

Synonym: CV_3837

Alternate gene names: 34499292

Gene position: 4139367-4140527 (Clockwise)

Preceding gene: 34499291

Following gene: 34499293

Centisome position: 87.12

GC content: 70.11

Gene sequence:

>1161_bases
ATGACCGACCCGCGCCACGCCCACCAGGGCCTGCCCGAACTCCATCTGCACCACACCCGCCGCGGCATGGTGGCGCGCAA
GGCCCGCATCGCCGCCGTCATCGCCGTCGCGCTGCTGCTGCTGGGACTCGGCCGCACGCTGCTGGCGCGCCACGCCAACG
CCGAGGCGCTGGCCCGCGAAGCGGCACGCAGCGCGGTGCTCACCGTCAGCGTGGTCACGCCGCGCCAGGGCCACGGCGAA
GCTTCGCTGACGCTGCCGGCCACGCTGCAGGGCATGGCGGAGGCGCAGATCTACGCCCGCACCAACGGCTACATCAAACG
CTGGCACAAGGACATCGGCCAGCCGGTGAAGAAGGGCGAACTGCTGGCAGAGCTGGACATTCCCGACATCGACAAGCAGG
TGCAGGAGGCGCAGGCCAATTTCAGCCTGGCCAAAACCGCCTACCTGCGCTGGAAAGCGCTGCGCGCGCAGGACGCGGTG
CCGCAGCAGGAATTCGACGAGAAGCAGGCCGCCTACCGGCAAACCGAGGCCGAGCTGAAGCGGCTGCGCGACCAGCAGGA
CTTCGCCCGCGTCGTCGCGCCGTTCGACGGCATCGTCACCCGCCGCAATATCGACACCGGCAGCCTGGTCAACGCCGGCA
ACGGCGGCAGCGCGCAAGCGCTGTTCGCCACCGCCCAGATCGACAAGCTGCACCTGTACGCTTACGTGCCGCAGTCGCGC
GCCGCCGACGTCCGCGTCGGCGAAACCGTCAGCATCGCGCGCCAGGAAGCGCCTGGCCATCCGGCCTCCGGCAAGGTGGT
TCGCACCGCCGGCGCCCTGGACCCGTCCACCCGCACGCTGCAAGTGGAGGTGGTGGTGGCCAATGCCGGCCACGGCCTGA
TGCCCGGCCAATACGTCGATGTCTCGTTCAAGCTGCCCGCCGGCGACAGCCTGACCCTGCCCACCAACACGCTGCAGTTC
GGCGCCAAGGGCAGCCGCGTCGCGCTGGCCGGCGCCGACGGCAAGGTCCATCTGCGGCCGGTGGCGATAGGCGTCGATTA
CGGCCACGAGGTGGAAATCCGCGCCGGCCTGAAGCCGGACGACAAGGTGATCGTCAACCCGCCGGACTCGATCAACGATG
GACAAGCGGTGACCGTGGTGCCCGCCGCCAAGGGGGAGTGA

Upstream 100 bases:

>100_bases
CTGTTCGTACCGGTGGTGTTCGCCAGCTTCCACCGCTACCTGGCTCAACGCAAACAACACGCGGCGGACGCGGCAAGCTC
CGCCGCGCAGGACGCATGAC

Downstream 100 bases:

>100_bases
GGCGATGCGCGCGCTTCCCCTGCTGCTCGCCGCCGCGCTGTCCGGCTGCGCCGCCGTCGGCCCCGACTACCGCCCCCCGG
CCAGCGAATTGCCGGCGCAG

Product: multidrug efflux membrane protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTDPRHAHQGLPELHLHHTRRGMVARKARIAAVIAVALLLLGLGRTLLARHANAEALAREAARSAVLTVSVVTPRQGHGE
ASLTLPATLQGMAEAQIYARTNGYIKRWHKDIGQPVKKGELLAELDIPDIDKQVQEAQANFSLAKTAYLRWKALRAQDAV
PQQEFDEKQAAYRQTEAELKRLRDQQDFARVVAPFDGIVTRRNIDTGSLVNAGNGGSAQALFATAQIDKLHLYAYVPQSR
AADVRVGETVSIARQEAPGHPASGKVVRTAGALDPSTRTLQVEVVVANAGHGLMPGQYVDVSFKLPAGDSLTLPTNTLQF
GAKGSRVALAGADGKVHLRPVAIGVDYGHEVEIRAGLKPDDKVIVNPPDSINDGQAVTVVPAAKGE

Sequences:

>Translated_386_residues
MTDPRHAHQGLPELHLHHTRRGMVARKARIAAVIAVALLLLGLGRTLLARHANAEALAREAARSAVLTVSVVTPRQGHGE
ASLTLPATLQGMAEAQIYARTNGYIKRWHKDIGQPVKKGELLAELDIPDIDKQVQEAQANFSLAKTAYLRWKALRAQDAV
PQQEFDEKQAAYRQTEAELKRLRDQQDFARVVAPFDGIVTRRNIDTGSLVNAGNGGSAQALFATAQIDKLHLYAYVPQSR
AADVRVGETVSIARQEAPGHPASGKVVRTAGALDPSTRTLQVEVVVANAGHGLMPGQYVDVSFKLPAGDSLTLPTNTLQF
GAKGSRVALAGADGKVHLRPVAIGVDYGHEVEIRAGLKPDDKVIVNPPDSINDGQAVTVVPAAKGE
>Mature_385_residues
TDPRHAHQGLPELHLHHTRRGMVARKARIAAVIAVALLLLGLGRTLLARHANAEALAREAARSAVLTVSVVTPRQGHGEA
SLTLPATLQGMAEAQIYARTNGYIKRWHKDIGQPVKKGELLAELDIPDIDKQVQEAQANFSLAKTAYLRWKALRAQDAVP
QQEFDEKQAAYRQTEAELKRLRDQQDFARVVAPFDGIVTRRNIDTGSLVNAGNGGSAQALFATAQIDKLHLYAYVPQSRA
ADVRVGETVSIARQEAPGHPASGKVVRTAGALDPSTRTLQVEVVVANAGHGLMPGQYVDVSFKLPAGDSLTLPTNTLQFG
AKGSRVALAGADGKVHLRPVAIGVDYGHEVEIRAGLKPDDKVIVNPPDSINDGQAVTVVPAAKGE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=321, Percent_Identity=25.8566978193146, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41345; Mature: 41213

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPRHAHQGLPELHLHHTRRGMVARKARIAAVIAVALLLLGLGRTLLARHANAEALARE
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
AARSAVLTVSVVTPRQGHGEASLTLPATLQGMAEAQIYARTNGYIKRWHKDIGQPVKKGE
HHCCEEEEEEEECCCCCCCCEEEECCHHHHCCHHEEEEEECCHHHHHHHHHHCCCHHCCC
LLAELDIPDIDKQVQEAQANFSLAKTAYLRWKALRAQDAVPQQEFDEKQAAYRQTEAELK
EEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLRDQQDFARVVAPFDGIVTRRNIDTGSLVNAGNGGSAQALFATAQIDKLHLYAYVPQSR
HHHCHHHHHHHHCCCCCEEEECCCCCCCEEECCCCCCCEEEEEEEEECEEEEEEECCCCC
AADVRVGETVSIARQEAPGHPASGKVVRTAGALDPSTRTLQVEVVVANAGHGLMPGQYVD
CCCEECCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCEEE
VSFKLPAGDSLTLPTNTLQFGAKGSRVALAGADGKVHLRPVAIGVDYGHEVEIRAGLKPD
EEEECCCCCEEECCCCCEEECCCCCEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCC
DKVIVNPPDSINDGQAVTVVPAAKGE
CCEEECCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TDPRHAHQGLPELHLHHTRRGMVARKARIAAVIAVALLLLGLGRTLLARHANAEALARE
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
AARSAVLTVSVVTPRQGHGEASLTLPATLQGMAEAQIYARTNGYIKRWHKDIGQPVKKGE
HHCCEEEEEEEECCCCCCCCEEEECCHHHHCCHHEEEEEECCHHHHHHHHHHCCCHHCCC
LLAELDIPDIDKQVQEAQANFSLAKTAYLRWKALRAQDAVPQQEFDEKQAAYRQTEAELK
EEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLRDQQDFARVVAPFDGIVTRRNIDTGSLVNAGNGGSAQALFATAQIDKLHLYAYVPQSR
HHHCHHHHHHHHCCCCCEEEECCCCCCCEEECCCCCCCEEEEEEEEECEEEEEEECCCCC
AADVRVGETVSIARQEAPGHPASGKVVRTAGALDPSTRTLQVEVVVANAGHGLMPGQYVD
CCCEECCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCEEE
VSFKLPAGDSLTLPTNTLQFGAKGSRVALAGADGKVHLRPVAIGVDYGHEVEIRAGLKPD
EEEECCCCCEEECCCCCEEECCCCCEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCC
DKVIVNPPDSINDGQAVTVVPAAKGE
CCEEECCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]