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The map label for this gene is hofF [H]

Identifier: 34499267

GI number: 34499267

Start: 4109085

End: 4110296

Strand: Reverse

Name: hofF [H]

Synonym: CV_3812

Alternate gene names: 34499267

Gene position: 4110296-4109085 (Counterclockwise)

Preceding gene: 34499268

Following gene: 34499266

Centisome position: 86.51

GC content: 69.39

Gene sequence:

>1212_bases
ATGGCGGCGTTCAAGTACACCGCCTACGACGCGGCGGGCAAGGAGCAGAGCGGGCTGCTGGAGGCCGACTCCGCGCGCGC
CGCGCGCGCGCAGCTCAGGGAGCGCGGCCTGCTGCCGGTCACCGTGGACGGCGTCAGCGCCAAGACCGGCGGCGCCGGCA
GCAATGTGTTGCGCCGCGGCCTGCCGCGCGCCGAGCTGGTGATGATCACCGAGCAGCTGTCGACGCTGCTCAACGCCGGC
CTGACGCTGGAAAAGGCGTTGACCGCGGTGACCGAGCAATCGGAAAACGCCCGCAGCCGCACCGTGCTGGCGGCGCTGCG
CAGCGACATCCTGGAAGGCAAGGGCTTCGCCCAGGCGCTGTCGTCGGCGCCCGGCGTGTTCTCGCCGCTGTACCGCTCGC
TGGTGCAGGCCGGCGAACAATCCGGCCACCTGGACATGGTGATGTCGCGGCTGGCCGAATACCTGGACAAGCGGCAGAAC
ACCCAGCAGAAAGTGACGCTGGCGCTCGCCTATCCGGCGGTGGTGACGCTGGTGGCCATCCTGGTGGTGGCCGGCCTGAT
GAGCTACGTGGTGCCGCAGGTGGTCAGCGTGTTCGCCCAGACCAAGCAGAGCCTGCCTTTCCTGACCCGCGCGCTGGTGG
CCTGCAGCGATTTCCTGCGCCAGTGGGGCGTGGCGCTGCTGATCGGCATCGCCGCCGCGGCGTTCCTGATCGTCCGCGCC
CTGCGCGCGCCGGCGCTGAAGCGGCGCTTCCACGCCAGGGTGCTGAAGCTGCCGGTGTTCGGCCGGCTGTTCCGCGCGCT
CAACACCGCGCGCATGGCCAGCACCCTGTCCATCCTGGTCGGCTCCGGCGTGCCGCTGCTGACCGCGCTGGAGACGGCGC
GCGGCCTGATGACCATGCTGCCGATGCAGGACGCGGTGGCCGATGCGATGGCCAAGGTGCGCGAGGGTGTGTCCTTGTCG
CGCGCGCTCAATGCCAGCCGCCAGTTCCCGCCGGTGCTGATCCACCTGATTTCCAGCGGCGAGGCCAGCGGCACCTTGTC
CCACATGCTGGACCGCGCCGCCCAGCAGCAGGAGCAGGAGGTGGAGCGCAAGCTGGCCACCTTCACCACGCTGATGGAGC
CGCTGCTGATCCTGGTGATGGGCGGCATGGTGCTGTTGATCGTGCTGGCCATCATGATGCCCATCATCGACATGAACCAG
ATGGTGCATTGA

Upstream 100 bases:

>100_bases
CCGACCGCCACGGCATGCGCAGCCTGCGCGACGACGGCATGCGCTGGGTCAAGGCCGGCGAGACCAGCCTGGAAGAAATC
CTGCGGGTGACGAGGAGCTG

Downstream 100 bases:

>100_bases
GTGCCCGCCATGGCGGCACGCATTCCGATTACCCATTGAAGCAACCCGGCGGCGAGCCCGCCGGACATGAAAGACGGAGA
TACGATGAAACAGCTCAAAC

Product: general secretion pathway protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAAFKYTAYDAAGKEQSGLLEADSARAARAQLRERGLLPVTVDGVSAKTGGAGSNVLRRGLPRAELVMITEQLSTLLNAG
LTLEKALTAVTEQSENARSRTVLAALRSDILEGKGFAQALSSAPGVFSPLYRSLVQAGEQSGHLDMVMSRLAEYLDKRQN
TQQKVTLALAYPAVVTLVAILVVAGLMSYVVPQVVSVFAQTKQSLPFLTRALVACSDFLRQWGVALLIGIAAAAFLIVRA
LRAPALKRRFHARVLKLPVFGRLFRALNTARMASTLSILVGSGVPLLTALETARGLMTMLPMQDAVADAMAKVREGVSLS
RALNASRQFPPVLIHLISSGEASGTLSHMLDRAAQQQEQEVERKLATFTTLMEPLLILVMGGMVLLIVLAIMMPIIDMNQ
MVH

Sequences:

>Translated_403_residues
MAAFKYTAYDAAGKEQSGLLEADSARAARAQLRERGLLPVTVDGVSAKTGGAGSNVLRRGLPRAELVMITEQLSTLLNAG
LTLEKALTAVTEQSENARSRTVLAALRSDILEGKGFAQALSSAPGVFSPLYRSLVQAGEQSGHLDMVMSRLAEYLDKRQN
TQQKVTLALAYPAVVTLVAILVVAGLMSYVVPQVVSVFAQTKQSLPFLTRALVACSDFLRQWGVALLIGIAAAAFLIVRA
LRAPALKRRFHARVLKLPVFGRLFRALNTARMASTLSILVGSGVPLLTALETARGLMTMLPMQDAVADAMAKVREGVSLS
RALNASRQFPPVLIHLISSGEASGTLSHMLDRAAQQQEQEVERKLATFTTLMEPLLILVMGGMVLLIVLAIMMPIIDMNQ
MVH
>Mature_402_residues
AAFKYTAYDAAGKEQSGLLEADSARAARAQLRERGLLPVTVDGVSAKTGGAGSNVLRRGLPRAELVMITEQLSTLLNAGL
TLEKALTAVTEQSENARSRTVLAALRSDILEGKGFAQALSSAPGVFSPLYRSLVQAGEQSGHLDMVMSRLAEYLDKRQNT
QQKVTLALAYPAVVTLVAILVVAGLMSYVVPQVVSVFAQTKQSLPFLTRALVACSDFLRQWGVALLIGIAAAAFLIVRAL
RAPALKRRFHARVLKLPVFGRLFRALNTARMASTLSILVGSGVPLLTALETARGLMTMLPMQDAVADAMAKVREGVSLSR
ALNASRQFPPVLIHLISSGEASGTLSHMLDRAAQQQEQEVERKLATFTTLMEPLLILVMGGMVLLIVLAIMMPIIDMNQM
VH

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=402, Percent_Identity=37.5621890547264, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1786295, Length=399, Percent_Identity=26.5664160401003, Blast_Score=154, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR011850
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43271; Mature: 43140

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFKYTAYDAAGKEQSGLLEADSARAARAQLRERGLLPVTVDGVSAKTGGAGSNVLRRG
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHC
LPRAELVMITEQLSTLLNAGLTLEKALTAVTEQSENARSRTVLAALRSDILEGKGFAQAL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
SSAPGVFSPLYRSLVQAGEQSGHLDMVMSRLAEYLDKRQNTQQKVTLALAYPAVVTLVAI
HCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LVVAGLMSYVVPQVVSVFAQTKQSLPFLTRALVACSDFLRQWGVALLIGIAAAAFLIVRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRAPALKRRFHARVLKLPVFGRLFRALNTARMASTLSILVGSGVPLLTALETARGLMTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
PMQDAVADAMAKVREGVSLSRALNASRQFPPVLIHLISSGEASGTLSHMLDRAAQQQEQE
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VERKLATFTTLMEPLLILVMGGMVLLIVLAIMMPIIDMNQMVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAFKYTAYDAAGKEQSGLLEADSARAARAQLRERGLLPVTVDGVSAKTGGAGSNVLRRG
CCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHC
LPRAELVMITEQLSTLLNAGLTLEKALTAVTEQSENARSRTVLAALRSDILEGKGFAQAL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
SSAPGVFSPLYRSLVQAGEQSGHLDMVMSRLAEYLDKRQNTQQKVTLALAYPAVVTLVAI
HCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LVVAGLMSYVVPQVVSVFAQTKQSLPFLTRALVACSDFLRQWGVALLIGIAAAAFLIVRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRAPALKRRFHARVLKLPVFGRLFRALNTARMASTLSILVGSGVPLLTALETARGLMTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
PMQDAVADAMAKVREGVSLSRALNASRQFPPVLIHLISSGEASGTLSHMLDRAAQQQEQE
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VERKLATFTTLMEPLLILVMGGMVLLIVLAIMMPIIDMNQMVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]