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The map label for this gene is arcD [H]

Identifier: 34499238

GI number: 34499238

Start: 4078890

End: 4080311

Strand: Reverse

Name: arcD [H]

Synonym: CV_3783

Alternate gene names: 34499238

Gene position: 4080311-4078890 (Counterclockwise)

Preceding gene: 34499239

Following gene: 34499237

Centisome position: 85.88

GC content: 65.96

Gene sequence:

>1422_bases
GTGGCCGAGGGCGGATCGCCCAGGCTGAAGCTGGGCGCGCTGACGGCGCTGGTCGTCGGCTCCATGATAGGTGGCGGCAT
CTTCTCGTTGCCGCAGAACATGGCGGCGGGCGCCGGCGCTGGCGCGATCCTGATCGGTTGGGCGATCACCTTCGTCGGCA
TGCTGGCGCTGGCCTTCGTGTTCCAGATGCTTGCCTCGCGCAAGCCTGAAGTGTCCGGCGGCGTGTACGGTTACGCCAAG
GCCGGTTTCGGCGACTACATGGGCTTCAACTCGGCCTGGGGTTACTGGATTTCGGCCTGGATCGGCAACGTTTCCTATTT
CGTCGTGATGTTCTCGGCGCTGGGCTTCTGGGTGCCGGCCTTCGGCGACGGCAACACGCCGATCGCCATCGCCTGCGCCT
CGGTGCTGCTGTGGGCCCTGCACTTCCTGGTGCTGCGCGGCGTGCACGGCGCGGCCTTCATCAACACCATCACCACCATC
GCCAAGCTGGTGCCGCTCGCGCTGTTCATCGCGCTGATCGTGTTCGCCTTCAAGGTGGATACCTTCAGCCTGGACTTCTG
GGGCAGCGCCAAGCTCGGCTCCATCGTCGACCAGGTGAAGAGCACCATGCTGGTGACGGTATGGGTGTTCATCGGCATCG
AGGGCGCGTCGATGTTCTCCGGCCGCGCCGAGAGCATGAAGGACGTGGGCAAGGCCACCGTGATCGGCTTCCTGCTGACC
ATCGCGCTGCTGGTCGCCGTGTCGGTGCTGTCGCTGGGCGTGATGACCCAGGCTGAGCTGGCCGCGCTGAAGAACCCGTC
TACCGCCTACGTGCTGCAGAAAGCCTTCGGCACCTTCGGCGCCAACCTGATGAACGCGGGCCTGGTGATCTCCGTCGGCG
GCGCGCTCTTGGCCTGGACCCTGCTGGCCGCCGAAGCGCCCTACCTCGCCGGCAAGGACGGCGTGATGCCCAAGGTGTTC
GGCACCGTCAACGGCAACGACACCCCGGCCGCCTCGCTGTGGCTGACCAACGGCCTGATCCAGCTGTTCCTGCTGATCAC
GTTGAAGAGCTCGGCTGGCTACCTGGCGCTGCTGTCGCTGGCCACCTCGATGATCCTGATCCCCTACCTGCTGTGCGCCG
GCTACTCCTGGCTGGTGGCGCAACGCGGCGAGGGCTATGCCCAAGGCGAGGCCCGCGGCAAGGAGCTGGGCACCGCCATC
CTGGCCACCGTTTACGGCGCGTGGCTGATCTACGCCGCCGGACCCAAGTACCTGTTCCTGTCCATGGTGCTGTACGCCCC
CGGCCTGCTGTTCTACCTGTGGGCCAAGAAGGAGCAGGGCCAGAAACCGTTCAACCTGATCGAAGCCGTGCTGGCCGCCA
TCGTGGTGGTGCTGGCGGTGATCGCGGTCTACATGCTGGCCACCGGTCAGATCGGCCTGTAA

Upstream 100 bases:

>100_bases
TACCATAATTTCAGATGATAAGAATTTAATAATGTAATGCTCGGTTTACATCCCAGATTGGAGAATGAAAATGTCTACTG
AAACTGCAACCCAAGCCGGC

Downstream 100 bases:

>100_bases
GCGAAAGATTTTGAAACCAGTGGGGGCGGATGCCCGCCCCCGAAGTCAGACAAGACTCAAGGAGTAGCGTTATGACCAAG
TTTGGTGTTCATTCTGAATG

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAEGGSPRLKLGALTALVVGSMIGGGIFSLPQNMAAGAGAGAILIGWAITFVGMLALAFVFQMLASRKPEVSGGVYGYAK
AGFGDYMGFNSAWGYWISAWIGNVSYFVVMFSALGFWVPAFGDGNTPIAIACASVLLWALHFLVLRGVHGAAFINTITTI
AKLVPLALFIALIVFAFKVDTFSLDFWGSAKLGSIVDQVKSTMLVTVWVFIGIEGASMFSGRAESMKDVGKATVIGFLLT
IALLVAVSVLSLGVMTQAELAALKNPSTAYVLQKAFGTFGANLMNAGLVISVGGALLAWTLLAAEAPYLAGKDGVMPKVF
GTVNGNDTPAASLWLTNGLIQLFLLITLKSSAGYLALLSLATSMILIPYLLCAGYSWLVAQRGEGYAQGEARGKELGTAI
LATVYGAWLIYAAGPKYLFLSMVLYAPGLLFYLWAKKEQGQKPFNLIEAVLAAIVVVLAVIAVYMLATGQIGL

Sequences:

>Translated_473_residues
MAEGGSPRLKLGALTALVVGSMIGGGIFSLPQNMAAGAGAGAILIGWAITFVGMLALAFVFQMLASRKPEVSGGVYGYAK
AGFGDYMGFNSAWGYWISAWIGNVSYFVVMFSALGFWVPAFGDGNTPIAIACASVLLWALHFLVLRGVHGAAFINTITTI
AKLVPLALFIALIVFAFKVDTFSLDFWGSAKLGSIVDQVKSTMLVTVWVFIGIEGASMFSGRAESMKDVGKATVIGFLLT
IALLVAVSVLSLGVMTQAELAALKNPSTAYVLQKAFGTFGANLMNAGLVISVGGALLAWTLLAAEAPYLAGKDGVMPKVF
GTVNGNDTPAASLWLTNGLIQLFLLITLKSSAGYLALLSLATSMILIPYLLCAGYSWLVAQRGEGYAQGEARGKELGTAI
LATVYGAWLIYAAGPKYLFLSMVLYAPGLLFYLWAKKEQGQKPFNLIEAVLAAIVVVLAVIAVYMLATGQIGL
>Mature_472_residues
AEGGSPRLKLGALTALVVGSMIGGGIFSLPQNMAAGAGAGAILIGWAITFVGMLALAFVFQMLASRKPEVSGGVYGYAKA
GFGDYMGFNSAWGYWISAWIGNVSYFVVMFSALGFWVPAFGDGNTPIAIACASVLLWALHFLVLRGVHGAAFINTITTIA
KLVPLALFIALIVFAFKVDTFSLDFWGSAKLGSIVDQVKSTMLVTVWVFIGIEGASMFSGRAESMKDVGKATVIGFLLTI
ALLVAVSVLSLGVMTQAELAALKNPSTAYVLQKAFGTFGANLMNAGLVISVGGALLAWTLLAAEAPYLAGKDGVMPKVFG
TVNGNDTPAASLWLTNGLIQLFLLITLKSSAGYLALLSLATSMILIPYLLCAGYSWLVAQRGEGYAQGEARGKELGTAIL
ATVYGAWLIYAAGPKYLFLSMVLYAPGLLFYLWAKKEQGQKPFNLIEAVLAAIVVVLAVIAVYMLATGQIGL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=465, Percent_Identity=47.3118279569892, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI2367353, Length=452, Percent_Identity=28.7610619469027, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790575, Length=387, Percent_Identity=29.4573643410853, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1786908, Length=424, Percent_Identity=27.8301886792453, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082250, Length=372, Percent_Identity=27.1505376344086, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49621; Mature: 49490

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGGSPRLKLGALTALVVGSMIGGGIFSLPQNMAAGAGAGAILIGWAITFVGMLALAFV
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FQMLASRKPEVSGGVYGYAKAGFGDYMGFNSAWGYWISAWIGNVSYFVVMFSALGFWVPA
HHHHHCCCCCCCCCCCEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGDGNTPIAIACASVLLWALHFLVLRGVHGAAFINTITTIAKLVPLALFIALIVFAFKVD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TFSLDFWGSAKLGSIVDQVKSTMLVTVWVFIGIEGASMFSGRAESMKDVGKATVIGFLLT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHH
IALLVAVSVLSLGVMTQAELAALKNPSTAYVLQKAFGTFGANLMNAGLVISVGGALLAWT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCCCEEEECCHHHHHHH
LLAAEAPYLAGKDGVMPKVFGTVNGNDTPAASLWLTNGLIQLFLLITLKSSAGYLALLSL
HHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ATSMILIPYLLCAGYSWLVAQRGEGYAQGEARGKELGTAILATVYGAWLIYAAGPKYLFL
HHHHHHHHHHHHCCCHHEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SMVLYAPGLLFYLWAKKEQGQKPFNLIEAVLAAIVVVLAVIAVYMLATGQIGL
HHHHHHCHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEGGSPRLKLGALTALVVGSMIGGGIFSLPQNMAAGAGAGAILIGWAITFVGMLALAFV
CCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FQMLASRKPEVSGGVYGYAKAGFGDYMGFNSAWGYWISAWIGNVSYFVVMFSALGFWVPA
HHHHHCCCCCCCCCCCEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGDGNTPIAIACASVLLWALHFLVLRGVHGAAFINTITTIAKLVPLALFIALIVFAFKVD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TFSLDFWGSAKLGSIVDQVKSTMLVTVWVFIGIEGASMFSGRAESMKDVGKATVIGFLLT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHH
IALLVAVSVLSLGVMTQAELAALKNPSTAYVLQKAFGTFGANLMNAGLVISVGGALLAWT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCCCEEEECCHHHHHHH
LLAAEAPYLAGKDGVMPKVFGTVNGNDTPAASLWLTNGLIQLFLLITLKSSAGYLALLSL
HHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ATSMILIPYLLCAGYSWLVAQRGEGYAQGEARGKELGTAILATVYGAWLIYAAGPKYLFL
HHHHHHHHHHHHCCCHHEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SMVLYAPGLLFYLWAKKEQGQKPFNLIEAVLAAIVVVLAVIAVYMLATGQIGL
HHHHHHCHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]