Click here to switch to the map view.

The map label for this gene is deoC

Identifier: 34499156

GI number: 34499156

Start: 4000211

End: 4000978

Strand: Reverse

Name: deoC

Synonym: CV_3701

Alternate gene names: 34499156

Gene position: 4000978-4000211 (Counterclockwise)

Preceding gene: 34499157

Following gene: 34499155

Centisome position: 84.21

GC content: 67.71

Gene sequence:

>768_bases
ATGTCTGCACTGATTGAAGCCGCGCGCCGCGCGCTGTCCCTGATGGACCTGACCACCCTCAACGACGACGATACCGACGA
GAAGGTGGCCGCGCTGTGCCGCAAGGCCAAGAGCCCGGACGGCACCGTGGCGGCGGTATGCGTGTTTCCCCGCTTCGTGC
CCATCGCCAAGAAGACGCTGCGCGAAGCGGGTTGTCCGGAGGTGCAGGTGGCCACCGTCACCAACTTCCCGCACGGCAAT
GACGACGTCTCCATCGCGGTGGCCGAAACCCGCGCCGCCATCGCCTACGGCGCCGACGAAGTGGACGTGGTGTTCCCGTA
CCGCGCGCTGATGGCCGGCAACCGCGACATCGGCTTCGAGCTGGTCAAGGCCTGCAAGGAAGCCTGCGGCGGCAAGCTCT
TGAAAGTGATCATCGAGAGCGGCGAACTGAAGGACGCGGCGCTGATCCGCGAAGCCAGCGAGATTTCCATCCGCGCCGGG
GCCGACTTCATCAAGACTTCCACCGGCAAGGTGCCGGTCAACGCCACCTTGCCCGCGGCCGAGACCATGCTGGCCGTGAT
CAAGGAGCAGGGCGGCCAGTGCGGCTTCAAGGCCGCCGGCGGCGTCAAGAGCGCCACCGAGGCGGCCGAATACCTGGCCC
TGGCCGCGCGCCTGCTGGGCGAAGATTGGGTGAGCGCCCGCCACTTCCGCTTCGGCGCGTCCAGCCTGCTGGCCAATCTG
CAGATCGAGATCGCCGGCGGCGTCGCCAAGCCGAGCAGCGGCTACTGA

Upstream 100 bases:

>100_bases
TTGCTTTCACGTGAAGAAATTTTCATAATCGTGGGCATTGCCCTGGTCAAACCGCTGTCATGCGGTTTGCGCCTTTTGGA
CGCATACGAGAGAGATAGAC

Downstream 100 bases:

>100_bases
TCCATTCAAGAATTCGCGGGGTTACCGCAACTCTGGCCGGGCGATTTCCCGGCCGCACCGCCCATTGCCGTTTCATTCTG
CAGCGCGATGGGTATCAGGC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTLREAGCPEVQVATVTNFPHGN
DDVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFELVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAG
ADFIKTSTGKVPVNATLPAAETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANL
QIEIAGGVAKPSSGY

Sequences:

>Translated_255_residues
MSALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTLREAGCPEVQVATVTNFPHGN
DDVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFELVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAG
ADFIKTSTGKVPVNATLPAAETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANL
QIEIAGGVAKPSSGY
>Mature_254_residues
SALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTLREAGCPEVQVATVTNFPHGND
DVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFELVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAGA
DFIKTSTGKVPVNATLPAAETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANLQ
IEIAGGVAKPSSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=265, Percent_Identity=38.1132075471698, Blast_Score=168, Evalue=4e-42,
Organism=Escherichia coli, GI1790841, Length=259, Percent_Identity=67.1814671814672, Blast_Score=322, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17533015, Length=238, Percent_Identity=40.7563025210084, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI19922098, Length=269, Percent_Identity=36.8029739776952, Blast_Score=134, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_CHRVO (Q7NRS9)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903371.1
- ProteinModelPortal:   Q7NRS9
- SMR:   Q7NRS9
- GeneID:   2548213
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3701
- NMPDR:   fig|243365.1.peg.3701
- HOGENOM:   HBG636421
- OMA:   CKEACGD
- PhylomeDB:   Q7NRS9
- ProtClustDB:   PRK05283
- BioCyc:   CVIO243365:CV_3701-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 26702; Mature: 26571

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: ACT_SITE 165-165 ACT_SITE 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTL
CHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
REAGCPEVQVATVTNFPHGNDDVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHEEECCCCEEEEECHHHHHCCCCCCCHH
LVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAGADFIKTSTGKVPVNATLPAA
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCHHHCCCCCCCCCCCCCCHH
ETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANL
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
QIEIAGGVAKPSSGY
EEEEECCCCCCCCCC
>Mature Secondary Structure 
SALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTL
HHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
REAGCPEVQVATVTNFPHGNDDVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHEEECCCCEEEEECHHHHHCCCCCCCHH
LVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAGADFIKTSTGKVPVNATLPAA
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCHHHCCCCCCCCCCCCCCHH
ETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANL
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
QIEIAGGVAKPSSGY
EEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782