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The map label for this gene is argC

Identifier: 34499150

GI number: 34499150

Start: 3994359

End: 3995387

Strand: Reverse

Name: argC

Synonym: CV_3695

Alternate gene names: 34499150

Gene position: 3995387-3994359 (Counterclockwise)

Preceding gene: 34499151

Following gene: 34499149

Centisome position: 84.09

GC content: 67.25

Gene sequence:

>1029_bases
ATGGTCAAAGTTGGGATCGTTGGGGGCACCGGCTACACCGGTGTTGAGTTGCTGCGTTTGCTGGCCAAGCACCCGCAGGC
GTGCGTGACGGCGGTGACCTCGCGCAAGGATGCGGGCATTCGCGTCGACGAGATGTTTCCCAGCCTGCGCGGCCGCATCG
ATCTCGCCTTCACCACGCCGGACGAGGCGCGTCTGGCCGAGTGCGACGTGGTGTTCTTCGCCACGCCCAACGGCATCGCC
ATGCAGGATGCCGCCGCGCTGCTGGACGCCGGCGTGCGGGTGATCGACCTGGCGGCCGATTTCCGCATCAAGGACGTGTT
CGAGTGGGAGAAGTGGTACGGCATGCAGCATGCCTCGCCGCACCTGGTGGCCGACGCCGTCTACGGTCTGCCCGAGGTGA
ACCGCGAGGCGATCCGCAGCGCCCGCCTGGTGGCCAATCCCGGCTGCTATCCCACCGCGGTGCAACTGGGCTTCCTGCCC
TTGATCGAAGCCGGCGTCATCGATACGGCCAGCCTGATCGCCGACTGCAAGTCCGGCGTGTCCGGCGCCGGGCGCAAGGG
CGAGATCGGCGCCCTGCTGGCCGAGGCCGGCGATTCCTTCAAGGCTTATGGCGTGGCCGGCCATCGCCACCTGCCTGAAA
TCCGCCAGGGTCTGGCCCGCGCCAGCGGCAAGCCGGTGGGTCTGACCTTCGTGCCGCATCTGACGCCGATGATACGCGGC
ATCCACGCCACGCTGTACGCCAGGCTGACCAAGGACGTCGATCTGCAGCGGCTGTTCGAGAGCCGTTACGCCGATGAGTC
GTTTGTCGATGTGCTGCCGGCCGGCAGCCATCCCGAGACGCGCTCGGTGCGCGGCGCCAATCTGTGCCGCATCGCCGTCC
ACAGGCCGCAGGGCGGCGACACGGTGGTGGTATTGTCGGTGATCGACAACCTGGTCAAAGGCGCGGCGGGCCAGGCGGTG
CAGAACCTGAATCTGATGTTCGGTCTGCCGGAAAACGAGGGTCTGGATGTGGTGCCGCTGCTGCCTTGA

Upstream 100 bases:

>100_bases
TGGCTTTGCCCGGCGGTTTTTTCCATTTGTATGCTTGCCGCTACAGCCCGGCCTGCCTAAAATGTCGTCTTTGCGACATT
TTTTTACATAAAGGCTAGCC

Downstream 100 bases:

>100_bases
GCCGCGCAGGGCGTGCGCTCCGAAGGGGCGTTGCGCCATTCCCGCTCCGCAGTCAAGGCATAAGGGGCTTGAAGGCTCGC
CATCCGCCCCGATATCCGAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVKVGIVGGTGYTGVELLRLLAKHPQACVTAVTSRKDAGIRVDEMFPSLRGRIDLAFTTPDEARLAECDVVFFATPNGIA
MQDAAALLDAGVRVIDLAADFRIKDVFEWEKWYGMQHASPHLVADAVYGLPEVNREAIRSARLVANPGCYPTAVQLGFLP
LIEAGVIDTASLIADCKSGVSGAGRKGEIGALLAEAGDSFKAYGVAGHRHLPEIRQGLARASGKPVGLTFVPHLTPMIRG
IHATLYARLTKDVDLQRLFESRYADESFVDVLPAGSHPETRSVRGANLCRIAVHRPQGGDTVVVLSVIDNLVKGAAGQAV
QNLNLMFGLPENEGLDVVPLLP

Sequences:

>Translated_342_residues
MVKVGIVGGTGYTGVELLRLLAKHPQACVTAVTSRKDAGIRVDEMFPSLRGRIDLAFTTPDEARLAECDVVFFATPNGIA
MQDAAALLDAGVRVIDLAADFRIKDVFEWEKWYGMQHASPHLVADAVYGLPEVNREAIRSARLVANPGCYPTAVQLGFLP
LIEAGVIDTASLIADCKSGVSGAGRKGEIGALLAEAGDSFKAYGVAGHRHLPEIRQGLARASGKPVGLTFVPHLTPMIRG
IHATLYARLTKDVDLQRLFESRYADESFVDVLPAGSHPETRSVRGANLCRIAVHRPQGGDTVVVLSVIDNLVKGAAGQAV
QNLNLMFGLPENEGLDVVPLLP
>Mature_342_residues
MVKVGIVGGTGYTGVELLRLLAKHPQACVTAVTSRKDAGIRVDEMFPSLRGRIDLAFTTPDEARLAECDVVFFATPNGIA
MQDAAALLDAGVRVIDLAADFRIKDVFEWEKWYGMQHASPHLVADAVYGLPEVNREAIRSARLVANPGCYPTAVQLGFLP
LIEAGVIDTASLIADCKSGVSGAGRKGEIGALLAEAGDSFKAYGVAGHRHLPEIRQGLARASGKPVGLTFVPHLTPMIRG
IHATLYARLTKDVDLQRLFESRYADESFVDVLPAGSHPETRSVRGANLCRIAVHRPQGGDTVVVLSVIDNLVKGAAGQAV
QNLNLMFGLPENEGLDVVPLLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=36.9186046511628, Blast_Score=195, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6320913, Length=344, Percent_Identity=29.3604651162791, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_CHRVO (Q7NRT5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903365.1
- ProteinModelPortal:   Q7NRT5
- SMR:   Q7NRT5
- GeneID:   2548296
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3695
- NMPDR:   fig|243365.1.peg.3695
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   Q7NRT5
- ProtClustDB:   PRK00436
- BioCyc:   CVIO243365:CV_3695-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36489; Mature: 36489

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01224 ARGC; PS00136 SUBTILASE_ASP

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVGIVGGTGYTGVELLRLLAKHPQACVTAVTSRKDAGIRVDEMFPSLRGRIDLAFTTP
CEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEEECC
DEARLAECDVVFFATPNGIAMQDAAALLDAGVRVIDLAADFRIKDVFEWEKWYGMQHASP
CCCCEEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCC
HLVADAVYGLPEVNREAIRSARLVANPGCYPTAVQLGFLPLIEAGVIDTASLIADCKSGV
HHHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SGAGRKGEIGALLAEAGDSFKAYGVAGHRHLPEIRQGLARASGKPVGLTFVPHLTPMIRG
CCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHH
IHATLYARLTKDVDLQRLFESRYADESFVDVLPAGSHPETRSVRGANLCRIAVHRPQGGD
HHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCC
TVVVLSVIDNLVKGAAGQAVQNLNLMFGLPENEGLDVVPLLP
EEEEHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCEEECCC
>Mature Secondary Structure
MVKVGIVGGTGYTGVELLRLLAKHPQACVTAVTSRKDAGIRVDEMFPSLRGRIDLAFTTP
CEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHCCCEEEEEECC
DEARLAECDVVFFATPNGIAMQDAAALLDAGVRVIDLAADFRIKDVFEWEKWYGMQHASP
CCCCEEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCC
HLVADAVYGLPEVNREAIRSARLVANPGCYPTAVQLGFLPLIEAGVIDTASLIADCKSGV
HHHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SGAGRKGEIGALLAEAGDSFKAYGVAGHRHLPEIRQGLARASGKPVGLTFVPHLTPMIRG
CCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHH
IHATLYARLTKDVDLQRLFESRYADESFVDVLPAGSHPETRSVRGANLCRIAVHRPQGGD
HHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCC
TVVVLSVIDNLVKGAAGQAVQNLNLMFGLPENEGLDVVPLLP
EEEEHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782