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The map label for this gene is erpA

Identifier: 34499149

GI number: 34499149

Start: 3993852

End: 3994205

Strand: Reverse

Name: erpA

Synonym: CV_3694

Alternate gene names: 34499149

Gene position: 3994205-3993852 (Counterclockwise)

Preceding gene: 34499150

Following gene: 34499148

Centisome position: 84.07

GC content: 59.32

Gene sequence:

>354_bases
ATGACAGAAGCTGCTACCGAAATGCCGAGCCCGATCAACTTCACCGAGAGCGCTTGCGCCAAGGTGCAGGATCTGATCGC
GGAAGAGGGCAATCCCGACCTGAAACTGCGCGTGTTCGTCACCGGCGGCGGCTGTTCCGGCTTCCAGTACGGTTTCACGT
TCGATGAAATCGCCAACGAGGACGATACCGCTATCGAGCGCCAGGGCGTCACCTTCCTGGTCGATCCGATGAGCTACCAA
TACCTGGTCGGCGCCGAGATCGACTACCAGGAAAGCCTGGAAGGCTCCCAGTTCGTGATCCGCAACCCGAACGCCACCAC
CACTTGCGGTTGTGGTTCTTCGTTCTCGGTGTGA

Upstream 100 bases:

>100_bases
CAAGGCATAAGGGGCTTGAAGGCTCGCCATCCGCCCCGATATCCGACTAAAATAGTGGGTGAATGGCCGCGACCGGCCTG
ATTGAATTGCGAGGTTACAC

Downstream 100 bases:

>100_bases
TACTGAACCCAGGTAAGAACCAGGCCCGGGCCCTTGCCCCGGGCCTTTTTGCTGTGGAATCCAGGACATGAACAAGCTGC
CGCCGGTGGTATTGCCCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MTEAATEMPSPINFTESACAKVQDLIAEEGNPDLKLRVFVTGGGCSGFQYGFTFDEIANEDDTAIERQGVTFLVDPMSYQ
YLVGAEIDYQESLEGSQFVIRNPNATTTCGCGSSFSV

Sequences:

>Translated_117_residues
MTEAATEMPSPINFTESACAKVQDLIAEEGNPDLKLRVFVTGGGCSGFQYGFTFDEIANEDDTAIERQGVTFLVDPMSYQ
YLVGAEIDYQESLEGSQFVIRNPNATTTCGCGSSFSV
>Mature_116_residues
TEAATEMPSPINFTESACAKVQDLIAEEGNPDLKLRVFVTGGGCSGFQYGFTFDEIANEDDTAIERQGVTFLVDPMSYQY
LVGAEIDYQESLEGSQFVIRNPNATTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=41.1214953271028, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI52426768, Length=108, Percent_Identity=30.5555555555556, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786351, Length=107, Percent_Identity=66.3551401869159, Blast_Score=160, Evalue=2e-41,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=112, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25146411, Length=111, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=33.6448598130841, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=45.7831325301205, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.0275229357798, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_CHRVO (Q7NRT6)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903364.1
- HSSP:   O67709
- ProteinModelPortal:   Q7NRT6
- SMR:   Q7NRT6
- GeneID:   2548295
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3694
- NMPDR:   fig|243365.1.peg.3694
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   Q7NRT6
- BioCyc:   CVIO243365:CV_3694-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12643; Mature: 12512

Theoretical pI: Translated: 3.66; Mature: 3.66

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAATEMPSPINFTESACAKVQDLIAEEGNPDLKLRVFVTGGGCSGFQYGFTFDEIANE
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCC
DDTAIERQGVTFLVDPMSYQYLVGAEIDYQESLEGSQFVIRNPNATTTCGCGSSFSV
CCCEEECCCCEEEECCCCEEEEECCCCCHHHCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
TEAATEMPSPINFTESACAKVQDLIAEEGNPDLKLRVFVTGGGCSGFQYGFTFDEIANE
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCC
DDTAIERQGVTFLVDPMSYQYLVGAEIDYQESLEGSQFVIRNPNATTTCGCGSSFSV
CCCEEECCCCEEEECCCCEEEEECCCCCHHHCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782