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The map label for this gene is mgtC [H]

Identifier: 34498932

GI number: 34498932

Start: 3771567

End: 3772295

Strand: Reverse

Name: mgtC [H]

Synonym: CV_3477

Alternate gene names: 34498932

Gene position: 3772295-3771567 (Counterclockwise)

Preceding gene: 34498933

Following gene: 34498931

Centisome position: 79.4

GC content: 66.53

Gene sequence:

>729_bases
ATGCATTACAACCTGCACAATATGTTCGAGCTGGATTGGTTCGGCCTGCTGCATTCGCTGATCTGCCTGGCGATGGCCTT
CGCCTGCGGCACCGTGATCGGGCTGGAGCGGCAGTACCGCCAGCGCACCGCCGGCTTGCGCACCAACGCCCTGGTGGCGG
TGAGCGCGGCGGCCTTCGTCAATATGGCCTTGCAGCTGGACGGCTCAGGCAGCGCGTCGCGGGTGGTGGCTTACGTGGTG
TCCGGCGTGGGTTTTCTCGGTGCCGGCACCATCATGAAGGAGGGCTTGAACGTGCGCGGCCTGAACACCGCCGCCACGCT
GTGGGGCTCGGCGGCCACCGGCGCCTGCGCCGGCGCCGGCATGCTGGGCCAGGCCATCCTGACCACCGTGTTCGTGCTGG
CGGTGAACACGCTGCTGCGGCCGGTGGTCAACTCCATCAACCGCCGCCCGATAGACGACGACGCCAGCGAAGTCACTTAC
CAGCTGTGCGTGATCGCCACCCGCGAGGAGCAGAAGCAGGCGCTGGCCCAGGTGGGGCAATTGCTGGAGAAGGCCAATTA
CCCGGTGGGGGATCTGGATGTCGAGGCCTTCGGCGACGACGAGGTGGAGATGACCGCCACGCTGCTGGCCACCTCGGTGG
ATTCGGACGAACTGGACCGCATCGCCGCCGAGCTGGCGGCCAAGCCCTATATCAGCCAGGCATACTGGAACACCAGCACC
AGCGAGTGA

Upstream 100 bases:

>100_bases
TGGCGCCGGCTTTTGCCATATTAGGGACCGGTGCATGGTGGCTTTCGCGGAAAACCACCATGCATGTTCCTTATAAGAAA
CCGGATAACAAGGAGGACGC

Downstream 100 bases:

>100_bases
GCGCAAGTCTTTCCGGCATCCGCCGCCGCGGCCTTTAGGCGCCGGCGGCTTTTTTGCGTCCGATGCCGGGCGGGATAGCC
GGCCGCGCGCCTTGTCCGGG

Product: Mg2+ transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MHYNLHNMFELDWFGLLHSLICLAMAFACGTVIGLERQYRQRTAGLRTNALVAVSAAAFVNMALQLDGSGSASRVVAYVV
SGVGFLGAGTIMKEGLNVRGLNTAATLWGSAATGACAGAGMLGQAILTTVFVLAVNTLLRPVVNSINRRPIDDDASEVTY
QLCVIATREEQKQALAQVGQLLEKANYPVGDLDVEAFGDDEVEMTATLLATSVDSDELDRIAAELAAKPYISQAYWNTST
SE

Sequences:

>Translated_242_residues
MHYNLHNMFELDWFGLLHSLICLAMAFACGTVIGLERQYRQRTAGLRTNALVAVSAAAFVNMALQLDGSGSASRVVAYVV
SGVGFLGAGTIMKEGLNVRGLNTAATLWGSAATGACAGAGMLGQAILTTVFVLAVNTLLRPVVNSINRRPIDDDASEVTY
QLCVIATREEQKQALAQVGQLLEKANYPVGDLDVEAFGDDEVEMTATLLATSVDSDELDRIAAELAAKPYISQAYWNTST
SE
>Mature_242_residues
MHYNLHNMFELDWFGLLHSLICLAMAFACGTVIGLERQYRQRTAGLRTNALVAVSAAAFVNMALQLDGSGSASRVVAYVV
SGVGFLGAGTIMKEGLNVRGLNTAATLWGSAATGACAGAGMLGQAILTTVFVLAVNTLLRPVVNSINRRPIDDDASEVTY
QLCVIATREEQKQALAQVGQLLEKANYPVGDLDVEAFGDDEVEMTATLLATSVDSDELDRIAAELAAKPYISQAYWNTST
SE

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=118, Percent_Identity=44.0677966101695, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25755; Mature: 25755

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYNLHNMFELDWFGLLHSLICLAMAFACGTVIGLERQYRQRTAGLRTNALVAVSAAAFV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
NMALQLDGSGSASRVVAYVVSGVGFLGAGTIMKEGLNVRGLNTAATLWGSAATGACAGAG
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHH
MLGQAILTTVFVLAVNTLLRPVVNSINRRPIDDDASEVTYQLCVIATREEQKQALAQVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHH
LLEKANYPVGDLDVEAFGDDEVEMTATLLATSVDSDELDRIAAELAAKPYISQAYWNTST
HHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCC
SE
CC
>Mature Secondary Structure
MHYNLHNMFELDWFGLLHSLICLAMAFACGTVIGLERQYRQRTAGLRTNALVAVSAAAFV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
NMALQLDGSGSASRVVAYVVSGVGFLGAGTIMKEGLNVRGLNTAATLWGSAATGACAGAG
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHH
MLGQAILTTVFVLAVNTLLRPVVNSINRRPIDDDASEVTYQLCVIATREEQKQALAQVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHH
LLEKANYPVGDLDVEAFGDDEVEMTATLLATSVDSDELDRIAAELAAKPYISQAYWNTST
HHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCC
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA