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The map label for this gene is dppA [H]

Identifier: 34498881

GI number: 34498881

Start: 3718759

End: 3720339

Strand: Reverse

Name: dppA [H]

Synonym: CV_3426

Alternate gene names: 34498881

Gene position: 3720339-3718759 (Counterclockwise)

Preceding gene: 34498882

Following gene: 34498880

Centisome position: 78.31

GC content: 63.88

Gene sequence:

>1581_bases
ATGAAGAAACTGAGCGCCGCCGCGCTGGCGGTCCTGCCGCTGGCCGCCTTGGCGGCCAAACCCCTGACCGTATGCACCGA
CGCCAATCCGGAAGGTTTCGACGTGGTGCAGTACAACTCGCTGGTCACCACCAACGCCTCGGCAGACGTGTTGATGGACC
GCCTGGTGGAATACGACGCCGCCGCCGGCAAGCTGCGGCCGGGCCTGGCCGGCAGCTGGGAGGTCAGCGCCGACGGCCTG
GCTTACACCTTTCACCTGCGGTCCGGCGTCAGCTTCCACGGCACCGACTATTTCAAGCCGACGCGCAAGCTGAACGCCGA
CGACGTCGTGCAGACCTTCGACCGCATGCTGAATCCGGACAATGCCTGGTACAAGACCGCGCCCGCCGGCTATCCGCATG
CGCAGTCCATGCAGTTTCCCAAGCTGATCAAGGCGGTGCGCAAGCTGGATCCGCTGACGGTGCGCTTCGAGCTCAATTAC
CCGGAAGCCACCTTCTTGTCCAGCTTGACCATGGGCTTCGCCTCCATCTATTCCGCCGAATACATGGCCCAGCTGCTGGC
CGCGGGCAAGACCGGCGAACTCAACAGCAAGCCGATCGGCACCGGGCCTTTCGTGTTCAGGAGCTTCTCCAAGGACGCGC
TGGTGCGCTATGCGCCGAATCCGACCTACTTCGGCGCCAAGCCCAAGGTGTCGGCGCTGATCTACGCGATCACGCCGGAT
TCGAATGTCAGGCTGCAGAAGCTGCGCGCCGGCGAATGCCAGATCGCGCTGTCGCCCAAGCCGCAGGACGTGCAGGCGGC
CAAGACGGATGGCAGGCTGCAGGTGTCGCAGACGCCGGCCTTCATGACCGCCTTCGTCGCCTTCAACAGCCAGAAGAAGC
CGCTGGACAACCCGCAGGTGCGACAGGCGCTCAACCTCGCCTTCGACAAGGCCAATTATCTGAAGACGGTGTTCGGCAAT
ACAGCCGGGGCCGCCAGCCTGGTTTATCCGCCCAATACCTGGAGTTACGACAAGGCCATCAAGCCCTATGCCTATGATCC
GGCGCAGGCGAAGAAGCTGCTGGCGCAGGCGGGCTACCCCAACGGCTTCGACGCCACGGTATGGGTGCGCCCCAGCGGCA
GCACGCTGAATCCCAATCCCAAGGCCGGCGCGGAGATGTTGCAGGCGGACCTCGCCAAGGTGGGCGTCAAGCTGCAGATC
AAGGTGCTGGAGTGGGGCGAGCTGATCAAGCGCGGCAAGGCCGGCGAACACGAGATGCTGTTCATGGGCTGGGCCGGCGA
CAACGGCGACCCGGACAATTTCCTGACGCCGCAGTTTTCCTGCCCGGCGGTGCAGTCCGGCACCAATTTCGCCCGCTATT
GCGACGGCAGGCTGGACAAGCTGATCGCCGACGGCAAGAAGACCAGCGACTTCAAGACCCGGGCAAAGCTGTACCAGGCG
GCCCAGCGCATCATCCACGAGCAGGCGCTGTGGCTGCCGCTGGCGCATCCCATCGCCTATGGCTTGGCGCGCAAGGAGGT
GAGCGGCTACGCGGTCAATCCTTATGGACGGGTCAATTTCGTTAGTGTTGGCTTGAAATAA

Upstream 100 bases:

>100_bases
ATATCAATATGTGGATTAAATCATTGGTTTCTCCGTGCGCTTGGCTTACCCTATGCCGGTAATGCGGGCGGCATGTCCGC
CCGGCAGCTAGGAGAACAAT

Downstream 100 bases:

>100_bases
ACGACTTCTCGAGCAAGAATAGACCACTCCGTTTTATAAACAGAGTGGTCTCTTTCTTTTTTTGGAGCTTGCGCCAGAGC
AAAGCCGCACCCGTCGCGGG

Product: binding protein component of ABC dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKKLSAAALAVLPLAALAAKPLTVCTDANPEGFDVVQYNSLVTTNASADVLMDRLVEYDAAAGKLRPGLAGSWEVSADGL
AYTFHLRSGVSFHGTDYFKPTRKLNADDVVQTFDRMLNPDNAWYKTAPAGYPHAQSMQFPKLIKAVRKLDPLTVRFELNY
PEATFLSSLTMGFASIYSAEYMAQLLAAGKTGELNSKPIGTGPFVFRSFSKDALVRYAPNPTYFGAKPKVSALIYAITPD
SNVRLQKLRAGECQIALSPKPQDVQAAKTDGRLQVSQTPAFMTAFVAFNSQKKPLDNPQVRQALNLAFDKANYLKTVFGN
TAGAASLVYPPNTWSYDKAIKPYAYDPAQAKKLLAQAGYPNGFDATVWVRPSGSTLNPNPKAGAEMLQADLAKVGVKLQI
KVLEWGELIKRGKAGEHEMLFMGWAGDNGDPDNFLTPQFSCPAVQSGTNFARYCDGRLDKLIADGKKTSDFKTRAKLYQA
AQRIIHEQALWLPLAHPIAYGLARKEVSGYAVNPYGRVNFVSVGLK

Sequences:

>Translated_526_residues
MKKLSAAALAVLPLAALAAKPLTVCTDANPEGFDVVQYNSLVTTNASADVLMDRLVEYDAAAGKLRPGLAGSWEVSADGL
AYTFHLRSGVSFHGTDYFKPTRKLNADDVVQTFDRMLNPDNAWYKTAPAGYPHAQSMQFPKLIKAVRKLDPLTVRFELNY
PEATFLSSLTMGFASIYSAEYMAQLLAAGKTGELNSKPIGTGPFVFRSFSKDALVRYAPNPTYFGAKPKVSALIYAITPD
SNVRLQKLRAGECQIALSPKPQDVQAAKTDGRLQVSQTPAFMTAFVAFNSQKKPLDNPQVRQALNLAFDKANYLKTVFGN
TAGAASLVYPPNTWSYDKAIKPYAYDPAQAKKLLAQAGYPNGFDATVWVRPSGSTLNPNPKAGAEMLQADLAKVGVKLQI
KVLEWGELIKRGKAGEHEMLFMGWAGDNGDPDNFLTPQFSCPAVQSGTNFARYCDGRLDKLIADGKKTSDFKTRAKLYQA
AQRIIHEQALWLPLAHPIAYGLARKEVSGYAVNPYGRVNFVSVGLK
>Mature_526_residues
MKKLSAAALAVLPLAALAAKPLTVCTDANPEGFDVVQYNSLVTTNASADVLMDRLVEYDAAAGKLRPGLAGSWEVSADGL
AYTFHLRSGVSFHGTDYFKPTRKLNADDVVQTFDRMLNPDNAWYKTAPAGYPHAQSMQFPKLIKAVRKLDPLTVRFELNY
PEATFLSSLTMGFASIYSAEYMAQLLAAGKTGELNSKPIGTGPFVFRSFSKDALVRYAPNPTYFGAKPKVSALIYAITPD
SNVRLQKLRAGECQIALSPKPQDVQAAKTDGRLQVSQTPAFMTAFVAFNSQKKPLDNPQVRQALNLAFDKANYLKTVFGN
TAGAASLVYPPNTWSYDKAIKPYAYDPAQAKKLLAQAGYPNGFDATVWVRPSGSTLNPNPKAGAEMLQADLAKVGVKLQI
KVLEWGELIKRGKAGEHEMLFMGWAGDNGDPDNFLTPQFSCPAVQSGTNFARYCDGRLDKLIADGKKTSDFKTRAKLYQA
AQRIIHEQALWLPLAHPIAYGLARKEVSGYAVNPYGRVNFVSVGLK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=526, Percent_Identity=42.9657794676806, Blast_Score=467, Evalue=1e-132,
Organism=Escherichia coli, GI1787551, Length=511, Percent_Identity=33.8551859099804, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1787052, Length=529, Percent_Identity=29.6786389413989, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787762, Length=510, Percent_Identity=25.8823529411765, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1789887, Length=483, Percent_Identity=24.6376811594203, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789397, Length=498, Percent_Identity=25.5020080321285, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081878, Length=474, Percent_Identity=26.3713080168776, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=23.5621521335807, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57332; Mature: 57332

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSAAALAVLPLAALAAKPLTVCTDANPEGFDVVQYNSLVTTNASADVLMDRLVEYDA
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCEEECCCHHHHHHHHHHHHHC
AAGKLRPGLAGSWEVSADGLAYTFHLRSGVSFHGTDYFKPTRKLNADDVVQTFDRMLNPD
CCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
NAWYKTAPAGYPHAQSMQFPKLIKAVRKLDPLTVRFELNYPEATFLSSLTMGFASIYSAE
CCEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
YMAQLLAAGKTGELNSKPIGTGPFVFRSFSKDALVRYAPNPTYFGAKPKVSALIYAITPD
HHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEECCC
SNVRLQKLRAGECQIALSPKPQDVQAAKTDGRLQVSQTPAFMTAFVAFNSQKKPLDNPQV
CCCEEEEECCCCEEEEECCCCCCCHHCCCCCEEEEECCCHHHEEEEHCCCCCCCCCCHHH
RQALNLAFDKANYLKTVFGNTAGAASLVYPPNTWSYDKAIKPYAYDPAQAKKLLAQAGYP
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
NGFDATVWVRPSGSTLNPNPKAGAEMLQADLAKVGVKLQIKVLEWGELIKRGKAGEHEML
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECHHHHHHCCCCCCCEEE
FMGWAGDNGDPDNFLTPQFSCPAVQSGTNFARYCDGRLDKLIADGKKTSDFKTRAKLYQA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQRIIHEQALWLPLAHPIAYGLARKEVSGYAVNPYGRVNFVSVGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCC
>Mature Secondary Structure
MKKLSAAALAVLPLAALAAKPLTVCTDANPEGFDVVQYNSLVTTNASADVLMDRLVEYDA
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCEEECCCHHHHHHHHHHHHHC
AAGKLRPGLAGSWEVSADGLAYTFHLRSGVSFHGTDYFKPTRKLNADDVVQTFDRMLNPD
CCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
NAWYKTAPAGYPHAQSMQFPKLIKAVRKLDPLTVRFELNYPEATFLSSLTMGFASIYSAE
CCEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
YMAQLLAAGKTGELNSKPIGTGPFVFRSFSKDALVRYAPNPTYFGAKPKVSALIYAITPD
HHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEECCC
SNVRLQKLRAGECQIALSPKPQDVQAAKTDGRLQVSQTPAFMTAFVAFNSQKKPLDNPQV
CCCEEEEECCCCEEEEECCCCCCCHHCCCCCEEEEECCCHHHEEEEHCCCCCCCCCCHHH
RQALNLAFDKANYLKTVFGNTAGAASLVYPPNTWSYDKAIKPYAYDPAQAKKLLAQAGYP
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
NGFDATVWVRPSGSTLNPNPKAGAEMLQADLAKVGVKLQIKVLEWGELIKRGKAGEHEML
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECHHHHHHCCCCCCCEEE
FMGWAGDNGDPDNFLTPQFSCPAVQSGTNFARYCDGRLDKLIADGKKTSDFKTRAKLYQA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQRIIHEQALWLPLAHPIAYGLARKEVSGYAVNPYGRVNFVSVGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]