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The map label for this gene is fabD [H]

Identifier: 34498870

GI number: 34498870

Start: 3708385

End: 3709314

Strand: Reverse

Name: fabD [H]

Synonym: CV_3415

Alternate gene names: 34498870

Gene position: 3709314-3708385 (Counterclockwise)

Preceding gene: 34498871

Following gene: 34498869

Centisome position: 78.07

GC content: 68.92

Gene sequence:

>930_bases
ATGGCTTTTGCTTTTCTTTTTCCGGGACAGGGCTCGCAAAGCCTGAAAATGATGGACGGCTTCGCCGACCTGCCCGTGGT
GCAGCATACATTCGAAGAGGCGTCCGACACGCTGTCGCTGGATCTGTGGGCGATGCTGCGGGCGGATAGCGCCGACGCGA
TCAACGCCACCGTGAATACCCAGCCCATCATGCTGGCCGCCGGCTATGCCACTTACCTGGCATGGCAGGAGCTGAACGGC
AAGCAGCCGTCGGTGGTGGCCGGCCATAGCCTGGGCGAGTACACCGCGCTGGTGGCCGCCGGCGCGCTGCCGTTCGCCGA
GGCGGTGAAGCTGGTTCGCCTGCGCGCCGAGGCGATGCAGGCCGCGGTGCCGGCCGGCGCCGGCGCGATGGCCGCCATTC
TCAACCTGCCTGACGACGACATCCGCGCCGCCTGCGCGGAGGCCGCCCAAGGCGAGGTGGTGGAGGCCGTCAACTTCAAT
TCCCCGGGCCAGGTGGTGATCGCCGGCAACAAGGGCGCGGTGGAGCGCGCGATGGACCTGTGCAAGGAGAAGGGCGCCAA
GCGCGCGCTGCCGCTGCCGGTGTCGGTGCCTTCGCACTGCTCGCTGATGCGCCCGGCCGCCGAGCGCTTGGCCGAGGCGC
TGCGGGACGTGCATCTGAGCGCGCCCGCCGTTCCGGTGCTGCACAATGCCGACGTGGCCAGCTACAACGATGCCGCGCAG
ATCCGCGACGCGCTGACCCGCCAGCTGTTCATGCCGGTGCGCTGGACCGAAACCATTCAGAAGCTGGCCGCCGAAGGCGT
GACCCTGATGGCCGAGTGCGGTCCGGGCAAGGTGCTGACGGGCCTCGCCAAGCGCATCGACGGCAACGTCAAGTGCCTGG
CGCTGACTGACCGCGCCGCGCTGGAAGCCGCGCGCGAAGAGCTGGTCTGA

Upstream 100 bases:

>100_bases
CGCCGCATGATCGCCGATAATGACAGCGTTTATTGATCGGCGACGTGGCGCGCATGGCCGCTTTGCGTCATCCTTTGCGT
CGAATTCTGTGGAGTCGACT

Downstream 100 bases:

>100_bases
CGCGAAATTCCGGCGCGTCGGCTTTGTCCGGCGCGCCATCGCCTTGTCCCGCGCAAGCGGAACGGGGCGTCGACAACAAG
GAGACACATTGATGAGTCTG

Product: ACP S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAFAFLFPGQGSQSLKMMDGFADLPVVQHTFEEASDTLSLDLWAMLRADSADAINATVNTQPIMLAAGYATYLAWQELNG
KQPSVVAGHSLGEYTALVAAGALPFAEAVKLVRLRAEAMQAAVPAGAGAMAAILNLPDDDIRAACAEAAQGEVVEAVNFN
SPGQVVIAGNKGAVERAMDLCKEKGAKRALPLPVSVPSHCSLMRPAAERLAEALRDVHLSAPAVPVLHNADVASYNDAAQ
IRDALTRQLFMPVRWTETIQKLAAEGVTLMAECGPGKVLTGLAKRIDGNVKCLALTDRAALEAAREELV

Sequences:

>Translated_309_residues
MAFAFLFPGQGSQSLKMMDGFADLPVVQHTFEEASDTLSLDLWAMLRADSADAINATVNTQPIMLAAGYATYLAWQELNG
KQPSVVAGHSLGEYTALVAAGALPFAEAVKLVRLRAEAMQAAVPAGAGAMAAILNLPDDDIRAACAEAAQGEVVEAVNFN
SPGQVVIAGNKGAVERAMDLCKEKGAKRALPLPVSVPSHCSLMRPAAERLAEALRDVHLSAPAVPVLHNADVASYNDAAQ
IRDALTRQLFMPVRWTETIQKLAAEGVTLMAECGPGKVLTGLAKRIDGNVKCLALTDRAALEAAREELV
>Mature_308_residues
AFAFLFPGQGSQSLKMMDGFADLPVVQHTFEEASDTLSLDLWAMLRADSADAINATVNTQPIMLAAGYATYLAWQELNGK
QPSVVAGHSLGEYTALVAAGALPFAEAVKLVRLRAEAMQAAVPAGAGAMAAILNLPDDDIRAACAEAAQGEVVEAVNFNS
PGQVVIAGNKGAVERAMDLCKEKGAKRALPLPVSVPSHCSLMRPAAERLAEALRDVHLSAPAVPVLHNADVASYNDAAQI
RDALTRQLFMPVRWTETIQKLAAEGVTLMAECGPGKVLTGLAKRIDGNVKCLALTDRAALEAAREELV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=33.5548172757475, Blast_Score=148, Evalue=8e-36,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=56.0655737704918, Blast_Score=317, Evalue=5e-88,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=29.7297297297297, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=34.983498349835, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32526; Mature: 32395

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFAFLFPGQGSQSLKMMDGFADLPVVQHTFEEASDTLSLDLWAMLRADSADAINATVNT
CEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEHHHHHHHHCCCCCCEEEECCC
QPIMLAAGYATYLAWQELNGKQPSVVAGHSLGEYTALVAAGALPFAEAVKLVRLRAEAMQ
CCEEEEECHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAVPAGAGAMAAILNLPDDDIRAACAEAAQGEVVEAVNFNSPGQVVIAGNKGAVERAMDL
HHCCCCCCHHHHEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCHHHHHHHH
CKEKGAKRALPLPVSVPSHCSLMRPAAERLAEALRDVHLSAPAVPVLHNADVASYNDAAQ
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHH
IRDALTRQLFMPVRWTETIQKLAAEGVTLMAECGPGKVLTGLAKRIDGNVKCLALTDRAA
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHH
LEAAREELV
HHHHHHHCC
>Mature Secondary Structure 
AFAFLFPGQGSQSLKMMDGFADLPVVQHTFEEASDTLSLDLWAMLRADSADAINATVNT
EEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEHHHHHHHHCCCCCCEEEECCC
QPIMLAAGYATYLAWQELNGKQPSVVAGHSLGEYTALVAAGALPFAEAVKLVRLRAEAMQ
CCEEEEECHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAVPAGAGAMAAILNLPDDDIRAACAEAAQGEVVEAVNFNSPGQVVIAGNKGAVERAMDL
HHCCCCCCHHHHEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCHHHHHHHH
CKEKGAKRALPLPVSVPSHCSLMRPAAERLAEALRDVHLSAPAVPVLHNADVASYNDAAQ
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHH
IRDALTRQLFMPVRWTETIQKLAAEGVTLMAECGPGKVLTGLAKRIDGNVKCLALTDRAA
HHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHH
LEAAREELV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]