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The map label for this gene is frdD [H]

Identifier: 34498821

GI number: 34498821

Start: 3662625

End: 3662987

Strand: Reverse

Name: frdD [H]

Synonym: CV_3366

Alternate gene names: 34498821

Gene position: 3662987-3662625 (Counterclockwise)

Preceding gene: 34498822

Following gene: 34498820

Centisome position: 77.1

GC content: 68.87

Gene sequence:

>363_bases
ATGAAAAACCGCCAATTGAAGCGTTCCCACGCGCCCATCTTCTGGGGATTGTTCGGCGCAGGCGGCATGCTGGCCGCGCT
GTTCGGGCCGATGCTGGTGGCCATCACCGGCTTCGCCGCGCCGCTGGGCTGGCTGCCGGCCAAGGCCGCCAGCTACCAGG
GCGCGCTGGCGCTGGCGCAGAGCCTGACCGGCAAGCTGGTGTTGTGGGGACTGATCAGCCTGCTGCTGTGGCATGCGGCG
CACCGCATCTATCACAGTCTGCACGATGTCGGCGTGCATGGCGGCCCGCTGGCCAAGGCGCTGACCTATGGCGTGGCGGC
GGCGGGCACGCTGGCGGCGATGTGGCTGTTGGCCGGCATCTGA

Upstream 100 bases:

>100_bases
GCGGCAGGCGCGTCTCCGCCACCGCCATCACAGCCGGGGGCTTCGCCGCTACCTTGCTGGCCAGCCTGGCCTTGCTGGGC
GTCGTATGGGGGATCTCGCA

Downstream 100 bases:

>100_bases
GCCTTGTTCGATGAAAAGCCGACCGTGTCTGGCCCTTGGGGGCGGGGCGGTCGGCTTTGTCGCATGCCCCCGGCCATTCG
GACCGGCCGGGGCATGGGTG

Product: fumarate reductase subunit D

Products: fumarate; NADH; H+

Alternate protein names: Fumarate reductase 13 kDa hydrophobic protein [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MKNRQLKRSHAPIFWGLFGAGGMLAALFGPMLVAITGFAAPLGWLPAKAASYQGALALAQSLTGKLVLWGLISLLLWHAA
HRIYHSLHDVGVHGGPLAKALTYGVAAAGTLAAMWLLAGI

Sequences:

>Translated_120_residues
MKNRQLKRSHAPIFWGLFGAGGMLAALFGPMLVAITGFAAPLGWLPAKAASYQGALALAQSLTGKLVLWGLISLLLWHAA
HRIYHSLHDVGVHGGPLAKALTYGVAAAGTLAAMWLLAGI
>Mature_120_residues
MKNRQLKRSHAPIFWGLFGAGGMLAALFGPMLVAITGFAAPLGWLPAKAASYQGALALAQSLTGKLVLWGLISLLLWHAA
HRIYHSLHDVGVHGGPLAKALTYGVAAAGTLAAMWLLAGI

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=114, Percent_Identity=43.859649122807, Blast_Score=99, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.1.6

Molecular weight: Translated: 12522; Mature: 12522

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRQLKRSHAPIFWGLFGAGGMLAALFGPMLVAITGFAAPLGWLPAKAASYQGALALAQ
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SLTGKLVLWGLISLLLWHAAHRIYHSLHDVGVHGGPLAKALTYGVAAAGTLAAMWLLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNRQLKRSHAPIFWGLFGAGGMLAALFGPMLVAITGFAAPLGWLPAKAASYQGALALAQ
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SLTGKLVLWGLISLLLWHAAHRIYHSLHDVGVHGGPLAKALTYGVAAAGTLAAMWLLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; NAD+

Specific reaction: succinate + NAD+ = fumarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA