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The map label for this gene is argA [H]

Identifier: 34498810

GI number: 34498810

Start: 3651023

End: 3652330

Strand: Direct

Name: argA [H]

Synonym: CV_3355

Alternate gene names: 34498810

Gene position: 3651023-3652330 (Clockwise)

Preceding gene: 34498809

Following gene: 34498811

Centisome position: 76.85

GC content: 67.97

Gene sequence:

>1308_bases
ATGCTGACCCGCGAGTTCGTCCACACCTTCCGCGAAGCCGCCCCCTACATCAACGCCTACCGCGGCAAGACCTTCGTGCT
GGCCATGGGCGGCGAGAGCCTGCTGGACGGCGACTTTTCCAGCATGGCCCAGGACATCAACCTGCTGGTCAGCCTGGGCG
TGCGCATCGTGCTGGTGCACGGCATCCGCCCGCAGATCGAAACCCTGCTCAAGCGCCACGGCATCGCCCGCCTGTTCCAC
CGCGATCGCCGCGTCACCGACGCCGCTACCATGGACATCGTCAAGCAGGCGGCCGGCGCCACCCGCCATGACGTCGAGGC
CCGGCTGTCGATGGGCATGCCGCACTCGCCGATGCACGGCGCCCACCTGCGCGTGGCCGGCGGCAACTTCGTCACCGCCC
AGCCGCTCGGCGTGCTGGACGGCGTGGACATGCAGTACACCGGCCAGGTGCGGCGCGTGGACGCCGCGGCGATCCGCCAG
CGCCTGGACGCCGGGGAACTGGTGCTGCTGACCCCGGTCGGCTATTCGCTGACCGGCGAGAGCTTCAACCTGACCATGGA
AGAGCTGGCCACCCACGCCGCCATCGCGCTGAAGGCGGAGAAGCTGATCTTCGTCGTAGAAGGCCGCGGCGCGGTGGAGC
AGGACAGCGAGCTGATCAGCACGCTGACCGCCCAGCAAGCCGAGCAGCTGCTGCAGGCGGGCAGCCTGCAGGACGACGTC
GCCGCCTGCCTGCCCTATTGCATACGCGCCACCCGCGAAGGCATTCCCCGCGCCCACCTGGTCAGCCGCCATCAGGACGG
CGCGCTGCTGCTGGAGCACTTCACCCGCGGCGGCAACGGCACCATGATCGCCCGCGACCCGCTGGTCAAGGTCCGCCACG
CCAGCATAGAGGACGTAGGCGACATCATGGGGCTGATCCGCCCGCTGGAGGAACAGGGCATTCTGGTGCGCCGCAGCCGC
GAGCGGCTGGAGGTGGAGATAGGCGAATACTCGGTGCTGGAGCACGACGGCAAGATCTACGGCTGCGTGGCGATGCACCC
GTTCCCGGAAGCGGAGACGGCCGAACTGGCCTGCCTCGCCGTGTCGCAGGAAAAACGCGACGGCGGCTTCGGCGAGATGC
TGCTCAAGCACGTGGAATACCAGGCGCGCACCCAGGGCCTGCGATCGCTGTTCGTGCTGACCACCCAGACCTCGCACTGG
TTCGTCGAGCGTGGTTTCGCCGAGGCCGACAAGAGCTCGCTGCCGCTGGCGCGCCAGCAGTTTTACAATTACCAGCGCCG
CTCGAAGGTGTTCGTAAAGAAGCTGTAA

Upstream 100 bases:

>100_bases
ATTTTTCATGCAGGCGGGCTTACTTTCCGAAACACAATGCCGCGGCAATCCTGATATTCTTGATGGTTATCCATTCCTTC
CACCGGCCGGAGCCCGCCGC

Downstream 100 bases:

>100_bases
CAATTAACGGCGATGATGCCGCCACGGTTGGAACGGCGCAGGCTCTGTGACACAATAGCCTGTTGTTTCAATCCGATTCC
AAGCAAGGATTTCAAGCGAT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLTREFVHTFREAAPYINAYRGKTFVLAMGGESLLDGDFSSMAQDINLLVSLGVRIVLVHGIRPQIETLLKRHGIARLFH
RDRRVTDAATMDIVKQAAGATRHDVEARLSMGMPHSPMHGAHLRVAGGNFVTAQPLGVLDGVDMQYTGQVRRVDAAAIRQ
RLDAGELVLLTPVGYSLTGESFNLTMEELATHAAIALKAEKLIFVVEGRGAVEQDSELISTLTAQQAEQLLQAGSLQDDV
AACLPYCIRATREGIPRAHLVSRHQDGALLLEHFTRGGNGTMIARDPLVKVRHASIEDVGDIMGLIRPLEEQGILVRRSR
ERLEVEIGEYSVLEHDGKIYGCVAMHPFPEAETAELACLAVSQEKRDGGFGEMLLKHVEYQARTQGLRSLFVLTTQTSHW
FVERGFAEADKSSLPLARQQFYNYQRRSKVFVKKL

Sequences:

>Translated_435_residues
MLTREFVHTFREAAPYINAYRGKTFVLAMGGESLLDGDFSSMAQDINLLVSLGVRIVLVHGIRPQIETLLKRHGIARLFH
RDRRVTDAATMDIVKQAAGATRHDVEARLSMGMPHSPMHGAHLRVAGGNFVTAQPLGVLDGVDMQYTGQVRRVDAAAIRQ
RLDAGELVLLTPVGYSLTGESFNLTMEELATHAAIALKAEKLIFVVEGRGAVEQDSELISTLTAQQAEQLLQAGSLQDDV
AACLPYCIRATREGIPRAHLVSRHQDGALLLEHFTRGGNGTMIARDPLVKVRHASIEDVGDIMGLIRPLEEQGILVRRSR
ERLEVEIGEYSVLEHDGKIYGCVAMHPFPEAETAELACLAVSQEKRDGGFGEMLLKHVEYQARTQGLRSLFVLTTQTSHW
FVERGFAEADKSSLPLARQQFYNYQRRSKVFVKKL
>Mature_435_residues
MLTREFVHTFREAAPYINAYRGKTFVLAMGGESLLDGDFSSMAQDINLLVSLGVRIVLVHGIRPQIETLLKRHGIARLFH
RDRRVTDAATMDIVKQAAGATRHDVEARLSMGMPHSPMHGAHLRVAGGNFVTAQPLGVLDGVDMQYTGQVRRVDAAAIRQ
RLDAGELVLLTPVGYSLTGESFNLTMEELATHAAIALKAEKLIFVVEGRGAVEQDSELISTLTAQQAEQLLQAGSLQDDV
AACLPYCIRATREGIPRAHLVSRHQDGALLLEHFTRGGNGTMIARDPLVKVRHASIEDVGDIMGLIRPLEEQGILVRRSR
ERLEVEIGEYSVLEHDGKIYGCVAMHPFPEAETAELACLAVSQEKRDGGFGEMLLKHVEYQARTQGLRSLFVLTTQTSHW
FVERGFAEADKSSLPLARQQFYNYQRRSKVFVKKL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=435, Percent_Identity=48.0459770114943, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48184; Mature: 48184

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTREFVHTFREAAPYINAYRGKTFVLAMGGESLLDGDFSSMAQDINLLVSLGVRIVLVH
CCCHHHHHHHHHHCCHHHHCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCEEEEEEE
GIRPQIETLLKRHGIARLFHRDRRVTDAATMDIVKQAAGATRHDVEARLSMGMPHSPMHG
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
AHLRVAGGNFVTAQPLGVLDGVDMQYTGQVRRVDAAAIRQRLDAGELVLLTPVGYSLTGE
CEEEEECCCEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
SFNLTMEELATHAAIALKAEKLIFVVEGRGAVEQDSELISTLTAQQAEQLLQAGSLQDDV
CCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
AACLPYCIRATREGIPRAHLVSRHQDGALLLEHFTRGGNGTMIARDPLVKVRHASIEDVG
HHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHCCHHHHH
DIMGLIRPLEEQGILVRRSRERLEVEIGEYSVLEHDGKIYGCVAMHPFPEAETAELACLA
HHHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCCEEEEEEECCCCCCCCCCEEEEE
VSQEKRDGGFGEMLLKHVEYQARTQGLRSLFVLTTQTSHWFVERGFAEADKSSLPLARQQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHCCCHHCCCCCCCHHHHH
FYNYQRRSKVFVKKL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTREFVHTFREAAPYINAYRGKTFVLAMGGESLLDGDFSSMAQDINLLVSLGVRIVLVH
CCCHHHHHHHHHHCCHHHHCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCEEEEEEE
GIRPQIETLLKRHGIARLFHRDRRVTDAATMDIVKQAAGATRHDVEARLSMGMPHSPMHG
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
AHLRVAGGNFVTAQPLGVLDGVDMQYTGQVRRVDAAAIRQRLDAGELVLLTPVGYSLTGE
CEEEEECCCEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
SFNLTMEELATHAAIALKAEKLIFVVEGRGAVEQDSELISTLTAQQAEQLLQAGSLQDDV
CCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
AACLPYCIRATREGIPRAHLVSRHQDGALLLEHFTRGGNGTMIARDPLVKVRHASIEDVG
HHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHCCHHHHH
DIMGLIRPLEEQGILVRRSRERLEVEIGEYSVLEHDGKIYGCVAMHPFPEAETAELACLA
HHHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCCEEEEEEECCCCCCCCCCEEEEE
VSQEKRDGGFGEMLLKHVEYQARTQGLRSLFVLTTQTSHWFVERGFAEADKSSLPLARQQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHCCCHHCCCCCCCHHHHH
FYNYQRRSKVFVKKL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA