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The map label for this gene is aceB [H]

Identifier: 34498759

GI number: 34498759

Start: 3598025

End: 3599620

Strand: Direct

Name: aceB [H]

Synonym: CV_3304

Alternate gene names: 34498759

Gene position: 3598025-3599620 (Clockwise)

Preceding gene: 34498756

Following gene: 34498760

Centisome position: 75.73

GC content: 66.04

Gene sequence:

>1596_bases
ATGGCAGTCAATCTCCCGCAGGGCGTGGAAGTTCTCGCCGACATCACTCCGGCCTACGCCGAAATCCTCACCCCCGAGGC
GCTGGCCTTCGTCGCCAAGCTGCACCGCCGCTTCGAGCCGACGCGGCGCGAGCGCATCGCCGCCCGCGCCGCGCGCCAGG
CCGAGCTGGACGCCGGCAAGCTGCCGGACTTCCTGCCAGAAACCGCCGCCGTGCGCGCCGGCGACTGGAAGATCGCGCCG
CTGCCGGCGGACTTGCTGGACCGCCGCGTCGAAATCACCGGCCCGGTGGAGCGCAAGATGATGATCAACGCGCTGAACTC
CGGCGCCAAGAGCTTCATGGCCGACTTCGAGGACTCCAACTGCCCGAGCTGGGACAACCAGATCGCCGGCCAGATCAATG
TCCGCGACGCCTACCGCAAGACCATTTCCTTCCAGAGCCCGGAAGGCAAGCAGTACCGGCTGAACGACACCGTCGCCACC
CTGCTGCTGCGCCCGCGCGGCTGGCACCTGATGGAAAAGCACGTCAAGGTGGACGGCGAGATCGTGTCCGGCAGCCTGTT
CGACTTCGGCCTGTCGTTCTTCCACAACATCCATTACCTGCGCGAGCGCGGCAGCGCCACCTATTACTACCTGCCCAAGA
TGGAAAGCCATCTGGAAGCGCGGCTGTGGAATCAGGTGTTCGTGTTCGCCCAGGACGAGCTGAACATCCCGCAGGGCACG
ATCAAGGCCACGGTGCTGATCGAGACCATCCTCGCCGCCTTCGAGATGGACGAAATCCTCTACGAGCTGCGCGAGCATTC
CGCCGGCCTCAACGCCGGCCGTTGGGACTACATCTTCAGCTGCATCAAGAAGTTCAAGCAGAACCGCGACTTCTGCCTGG
CCAACCGCGCGCTGATCACGATGACCGTGCCCTTCATGCGCGCCTACGCGCTGCTGCTGCTGAAAACCTGCCACCACCGC
GACGCGCCGGCCATCGGCGGCATGGCGGCGCTGATTCCGATCAAGAACGACGCCGCCGCCAATGAAAAGGCGCTGGCCGG
CGTGAAGGCGGACAAGGAGCGCGACGCCACCGACGGCTACGACGGCGGCTGGGTGGCCCACCCAGGCCTGGTGCCGATCG
CAAACGCCGCCTTCACCGCCGCGCTGGGCGACGCGCCCAACCAGATCGCCAAGCAGCGCCCGGATGTGCAGGTGAGCGCC
GCCGACCTGCTGAACTTCCAGCCGGAAGCGCCGATCACCGAAGCGGGTCTCGCCATGAACATCAACGTCGGCATCCAGTA
CCTGGGCGCCTGGATTTCCGGCAACGGCTGCGTGCCCATCCACAACCTGATGGAAGACGCCGCCACCGCCGAGATCTCGC
GCTCGCAGATCTGGCAGTGGATACGCTCGCCCAAGGGCGTGCTGGACGACGGCCGCAAGGTGACGGTGGAGCTGTTCCGC
GAGCTGCAGGCCCGCGAAGTGGCCAAGCTGCAAGCCGAATACGGCGCGCGCTGGACCCGCCAATACGAGGACGCGGCCAG
GATGTTCGACTTGCTCACCACCTCGGACGACTTCGTCGAGTTCCTGACGCTGCCGGGCTACGAATACATCGCCTGA

Upstream 100 bases:

>100_bases
GTGCAATTCATGCCATTTCTTTTTACTCGCGCGGCGAATAGACTGTCAAACATTGCATTGCAGCATCATCATGTCATCTT
CTCTACACAGGAGCGCGCGC

Downstream 100 bases:

>100_bases
CCAGCCTTTCGGCCTTCCGAACGGCCCCTTCCGGGGCCGTTTGGCATTTTCAGCCACGCCGCCGGCGCCGGACGGCATGG
AACCGGCGCTTGCCAATCGG

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAVNLPQGVEVLADITPAYAEILTPEALAFVAKLHRRFEPTRRERIAARAARQAELDAGKLPDFLPETAAVRAGDWKIAP
LPADLLDRRVEITGPVERKMMINALNSGAKSFMADFEDSNCPSWDNQIAGQINVRDAYRKTISFQSPEGKQYRLNDTVAT
LLLRPRGWHLMEKHVKVDGEIVSGSLFDFGLSFFHNIHYLRERGSATYYYLPKMESHLEARLWNQVFVFAQDELNIPQGT
IKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKQNRDFCLANRALITMTVPFMRAYALLLLKTCHHR
DAPAIGGMAALIPIKNDAAANEKALAGVKADKERDATDGYDGGWVAHPGLVPIANAAFTAALGDAPNQIAKQRPDVQVSA
ADLLNFQPEAPITEAGLAMNINVGIQYLGAWISGNGCVPIHNLMEDAATAEISRSQIWQWIRSPKGVLDDGRKVTVELFR
ELQAREVAKLQAEYGARWTRQYEDAARMFDLLTTSDDFVEFLTLPGYEYIA

Sequences:

>Translated_531_residues
MAVNLPQGVEVLADITPAYAEILTPEALAFVAKLHRRFEPTRRERIAARAARQAELDAGKLPDFLPETAAVRAGDWKIAP
LPADLLDRRVEITGPVERKMMINALNSGAKSFMADFEDSNCPSWDNQIAGQINVRDAYRKTISFQSPEGKQYRLNDTVAT
LLLRPRGWHLMEKHVKVDGEIVSGSLFDFGLSFFHNIHYLRERGSATYYYLPKMESHLEARLWNQVFVFAQDELNIPQGT
IKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKQNRDFCLANRALITMTVPFMRAYALLLLKTCHHR
DAPAIGGMAALIPIKNDAAANEKALAGVKADKERDATDGYDGGWVAHPGLVPIANAAFTAALGDAPNQIAKQRPDVQVSA
ADLLNFQPEAPITEAGLAMNINVGIQYLGAWISGNGCVPIHNLMEDAATAEISRSQIWQWIRSPKGVLDDGRKVTVELFR
ELQAREVAKLQAEYGARWTRQYEDAARMFDLLTTSDDFVEFLTLPGYEYIA
>Mature_530_residues
AVNLPQGVEVLADITPAYAEILTPEALAFVAKLHRRFEPTRRERIAARAARQAELDAGKLPDFLPETAAVRAGDWKIAPL
PADLLDRRVEITGPVERKMMINALNSGAKSFMADFEDSNCPSWDNQIAGQINVRDAYRKTISFQSPEGKQYRLNDTVATL
LLRPRGWHLMEKHVKVDGEIVSGSLFDFGLSFFHNIHYLRERGSATYYYLPKMESHLEARLWNQVFVFAQDELNIPQGTI
KATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKQNRDFCLANRALITMTVPFMRAYALLLLKTCHHRD
APAIGGMAALIPIKNDAAANEKALAGVKADKERDATDGYDGGWVAHPGLVPIANAAFTAALGDAPNQIAKQRPDVQVSAA
DLLNFQPEAPITEAGLAMNINVGIQYLGAWISGNGCVPIHNLMEDAATAEISRSQIWQWIRSPKGVLDDGRKVTVELFRE
LQAREVAKLQAEYGARWTRQYEDAARMFDLLTTSDDFVEFLTLPGYEYIA

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=513, Percent_Identity=53.0214424951267, Blast_Score=531, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI17561814, Length=511, Percent_Identity=50.293542074364, Blast_Score=496, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71982926, Length=408, Percent_Identity=52.6960784313725, Blast_Score=419, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6322222, Length=530, Percent_Identity=48.4905660377358, Blast_Score=503, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6324212, Length=518, Percent_Identity=49.2277992277992, Blast_Score=502, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 59283; Mature: 59152

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNLPQGVEVLADITPAYAEILTPEALAFVAKLHRRFEPTRRERIAARAARQAELDAGK
CCCCCCCHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
LPDFLPETAAVRAGDWKIAPLPADLLDRRVEITGPVERKMMINALNSGAKSFMADFEDSN
CCCCCCCHHHEECCCEEEECCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
CPSWDNQIAGQINVRDAYRKTISFQSPEGKQYRLNDTVATLLLRPRGWHLMEKHVKVDGE
CCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCE
IVSGSLFDFGLSFFHNIHYLRERGSATYYYLPKMESHLEARLWNQVFVFAQDELNIPQGT
EECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHEEEEEECCCCCCCCH
IKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKQNRDFCLANRALIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCEEEE
MTVPFMRAYALLLLKTCHHRDAPAIGGMAALIPIKNDAAANEKALAGVKADKERDATDGY
EEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
DGGWVAHPGLVPIANAAFTAALGDAPNQIAKQRPDVQVSAADLLNFQPEAPITEAGLAMN
CCCEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCEEEE
INVGIQYLGAWISGNGCVPIHNLMEDAATAEISRSQIWQWIRSPKGVLDDGRKVTVELFR
EECCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ELQAREVAKLQAEYGARWTRQYEDAARMFDLLTTSDDFVEFLTLPGYEYIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCC
>Mature Secondary Structure 
AVNLPQGVEVLADITPAYAEILTPEALAFVAKLHRRFEPTRRERIAARAARQAELDAGK
CCCCCCHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
LPDFLPETAAVRAGDWKIAPLPADLLDRRVEITGPVERKMMINALNSGAKSFMADFEDSN
CCCCCCCHHHEECCCEEEECCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
CPSWDNQIAGQINVRDAYRKTISFQSPEGKQYRLNDTVATLLLRPRGWHLMEKHVKVDGE
CCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCE
IVSGSLFDFGLSFFHNIHYLRERGSATYYYLPKMESHLEARLWNQVFVFAQDELNIPQGT
EECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHEEEEEECCCCCCCCH
IKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKQNRDFCLANRALIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCEEEE
MTVPFMRAYALLLLKTCHHRDAPAIGGMAALIPIKNDAAANEKALAGVKADKERDATDGY
EEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
DGGWVAHPGLVPIANAAFTAALGDAPNQIAKQRPDVQVSAADLLNFQPEAPITEAGLAMN
CCCEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHCCCCCCCCCCCCEEEE
INVGIQYLGAWISGNGCVPIHNLMEDAATAEISRSQIWQWIRSPKGVLDDGRKVTVELFR
EECCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ELQAREVAKLQAEYGARWTRQYEDAARMFDLLTTSDDFVEFLTLPGYEYIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA