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The map label for this gene is rhtC [H]

Identifier: 34498695

GI number: 34498695

Start: 3520702

End: 3521325

Strand: Direct

Name: rhtC [H]

Synonym: CV_3240

Alternate gene names: 34498695

Gene position: 3520702-3521325 (Clockwise)

Preceding gene: 34498694

Following gene: 34498696

Centisome position: 74.1

GC content: 71.96

Gene sequence:

>624_bases
ATGACCTGGACCATTTGGCTGCAATTCGCCGGCGTGTGCATGCTGGGCGCGATGTCGCCCGGCCCCAGCCTGGCGATGGT
ATTGCAGCAGACCGCCCGCGGCGGACGCGGCGGCGGCCTGGCCGCCGCGATGGGCCACGCGCTGGGCGTGGGCCTGTACG
CGTTGGCCGCCGCCCAGGGGCTGGCGATGGTGATGGCGGCACATCCGCTGCTGTTCAAGATCATCTCCAGCCTCGGCGCC
GCCTATCTGGTGTGGCTGGGCGTGCAGGGCCTGCGGGCGGCGTCCCGCCCGGCGCGGGCCGCCAGCGGCGAAACCGCCGC
CGCCGCGCCGACCTCGGCCTGGCGCGCCGCGCGCACCGGCCTGGCCGTGTCGCTGTCCAACCCTCATTTGGCGGTGATGT
TCGTCGCCCTGCTCAGCCAGTTCGTCACTGCCGACATGCCCGCCAGCGGCCAAGCGCTGCTGATCGCCACCGCGATGGGG
CTGGACTTCGGCTGGTACGCGCTGCTGACGCTGCTGATTTCCCACCCGTCCATCCTGAGCGGCCTGCACCGCAAGAGCCG
GTGGATAGACGGCTGCGGCGGCGCGCTGATGCTGCTGCTGGGCCTGCGCATCCTAGTGGTGTGA

Upstream 100 bases:

>100_bases
CGGGGGACGCATAGCGGCTATCCGCCGATGGCGGTTCTGCCCGCCGCGTCCGCGCCATAGACTTTGTCCTGATTGTCATC
GAGCAAATAAGGAGAAAGTC

Downstream 100 bases:

>100_bases
CGATGACGGAGAAAACGATGGCATGGAATCCGCAAACCTTCGCCGCGCTGGCCGTGCGCCACGGCGGCGAGGTGCTGGAA
CACGACAAGCCGCTGCGCTC

Product: threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTWTIWLQFAGVCMLGAMSPGPSLAMVLQQTARGGRGGGLAAAMGHALGVGLYALAAAQGLAMVMAAHPLLFKIISSLGA
AYLVWLGVQGLRAASRPARAASGETAAAAPTSAWRAARTGLAVSLSNPHLAVMFVALLSQFVTADMPASGQALLIATAMG
LDFGWYALLTLLISHPSILSGLHRKSRWIDGCGGALMLLLGLRILVV

Sequences:

>Translated_207_residues
MTWTIWLQFAGVCMLGAMSPGPSLAMVLQQTARGGRGGGLAAAMGHALGVGLYALAAAQGLAMVMAAHPLLFKIISSLGA
AYLVWLGVQGLRAASRPARAASGETAAAAPTSAWRAARTGLAVSLSNPHLAVMFVALLSQFVTADMPASGQALLIATAMG
LDFGWYALLTLLISHPSILSGLHRKSRWIDGCGGALMLLLGLRILVV
>Mature_206_residues
TWTIWLQFAGVCMLGAMSPGPSLAMVLQQTARGGRGGGLAAAMGHALGVGLYALAAAQGLAMVMAAHPLLFKIISSLGAA
YLVWLGVQGLRAASRPARAASGETAAAAPTSAWRAARTGLAVSLSNPHLAVMFVALLSQFVTADMPASGQALLIATAMGL
DFGWYALLTLLISHPSILSGLHRKSRWIDGCGGALMLLLGLRILVV

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=202, Percent_Identity=27.2277227722772, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788099, Length=182, Percent_Identity=28.021978021978, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786522, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21247; Mature: 21115

Theoretical pI: Translated: 11.33; Mature: 11.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWTIWLQFAGVCMLGAMSPGPSLAMVLQQTARGGRGGGLAAAMGHALGVGLYALAAAQG
CEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAMVMAAHPLLFKIISSLGAAYLVWLGVQGLRAASRPARAASGETAAAAPTSAWRAARTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
LAVSLSNPHLAVMFVALLSQFVTADMPASGQALLIATAMGLDFGWYALLTLLISHPSILS
EEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCCHHHH
GLHRKSRWIDGCGGALMLLLGLRILVV
HHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TWTIWLQFAGVCMLGAMSPGPSLAMVLQQTARGGRGGGLAAAMGHALGVGLYALAAAQG
EEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAMVMAAHPLLFKIISSLGAAYLVWLGVQGLRAASRPARAASGETAAAAPTSAWRAARTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
LAVSLSNPHLAVMFVALLSQFVTADMPASGQALLIATAMGLDFGWYALLTLLISHPSILS
EEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCCHHHH
GLHRKSRWIDGCGGALMLLLGLRILVV
HHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]