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The map label for this gene is leuO [H]

Identifier: 34498609

GI number: 34498609

Start: 3439677

End: 3440615

Strand: Reverse

Name: leuO [H]

Synonym: CV_3154

Alternate gene names: 34498609

Gene position: 3440615-3439677 (Counterclockwise)

Preceding gene: 34498614

Following gene: 34498607

Centisome position: 72.42

GC content: 71.78

Gene sequence:

>939_bases
ATGAAGAATATTCATCCCGGTCTGCGCGGCCTGGATCTCAACCTGTTGCTGCTGCTGGACGCGCTGTTCCGAGCCGGCTC
GGTGCAGGGCGCGGCGGACAGTCTGGCGATCAGCGCCTCCGCCTGCAGCCACGCGCTGGCGCGTCTGCGCCTGGCTTTGG
GCGACCAGCTGTTCGTGCGGGTGGGCGGCGGGATGCGGCCGACGCCGAGGGCGGAACAGCTGGCGCCGCTGGTGGAGGCG
GCATTGGCATTGCTGTCCGACGGCCTGGCGCGGGGCGCGGAGTTCGATCCGGCCCGCAGCGAGCGCCGCTTCGTGCTGGC
CGCCACCGACTACACCGCTTTCGCCGTATTGCCGCGCTTCCTGAACCGGATGCAGTCGCTGGCGCCGGCGCTGAGCTTTC
GCGTGCTGCAGGCGGAGCGCAAGGTGCCGCTGGATGCGCTGCTGGCCGGCAGCATCGATTTCGCGCTCGGCTACTCGGAG
GAAGACGGGCCGCCGCCGGCGGATATCGAGGAGTTCGATTGGCCGGAGGAGGAGTACGTGGCGATCGCCAGCCGCGATCA
TCCGCGCATCCGGGGCCGGCTGAGCCTGGAGGCCTACCTGGCGGAGCGCCATGCGGTGGTGACGCCGTGGAGCGAGCCGC
GCGGGGTGGTGGACCTGGTGTTGGAGAGGATGGGCCTGGCGCGGAGCGTGGCGCTGCAGCTGCCGTCGGTGCTGGCGGCG
CCCTTCGTCATCGGCGGCAGCGAGCTGATCATGACGCTGCCCAGGCGCGCGGCGCAGCGCTTGGCCGAAGCCGCGGGGGT
GCGGCTGTATCCGGCGCCCTTCGCCATTCCGCCGTACCGGCTGAAACTGTACCGCCATCGCCGGCACGCGGGCTCGGCCG
CGCACGACTGGGTGTGGCGGCAGCTGGCGGCCTGCGGGCCGGAAGCGCGTTCCCCATGA

Upstream 100 bases:

>100_bases
AAATCTGCATGCGTCGTTTCCCGTGGATGGTCGAAATGTCGGTTTCGGACATCTTAGTGCAAGCATTAAAATGCAAACAG
TGCATTGTTTTCAGGTAAAA

Downstream 100 bases:

>100_bases
AAAAGGCCGGCATGGCCGGCCCGGTTGAAGAGGCGTTGGGGATCAGCCGGCCAGCCAGCTGCCGGGATGGGATTCCAGCC
AGGTCCTGATGTTCTTGGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKNIHPGLRGLDLNLLLLLDALFRAGSVQGAADSLAISASACSHALARLRLALGDQLFVRVGGGMRPTPRAEQLAPLVEA
ALALLSDGLARGAEFDPARSERRFVLAATDYTAFAVLPRFLNRMQSLAPALSFRVLQAERKVPLDALLAGSIDFALGYSE
EDGPPPADIEEFDWPEEEYVAIASRDHPRIRGRLSLEAYLAERHAVVTPWSEPRGVVDLVLERMGLARSVALQLPSVLAA
PFVIGGSELIMTLPRRAAQRLAEAAGVRLYPAPFAIPPYRLKLYRHRRHAGSAAHDWVWRQLAACGPEARSP

Sequences:

>Translated_312_residues
MKNIHPGLRGLDLNLLLLLDALFRAGSVQGAADSLAISASACSHALARLRLALGDQLFVRVGGGMRPTPRAEQLAPLVEA
ALALLSDGLARGAEFDPARSERRFVLAATDYTAFAVLPRFLNRMQSLAPALSFRVLQAERKVPLDALLAGSIDFALGYSE
EDGPPPADIEEFDWPEEEYVAIASRDHPRIRGRLSLEAYLAERHAVVTPWSEPRGVVDLVLERMGLARSVALQLPSVLAA
PFVIGGSELIMTLPRRAAQRLAEAAGVRLYPAPFAIPPYRLKLYRHRRHAGSAAHDWVWRQLAACGPEARSP
>Mature_312_residues
MKNIHPGLRGLDLNLLLLLDALFRAGSVQGAADSLAISASACSHALARLRLALGDQLFVRVGGGMRPTPRAEQLAPLVEA
ALALLSDGLARGAEFDPARSERRFVLAATDYTAFAVLPRFLNRMQSLAPALSFRVLQAERKVPLDALLAGSIDFALGYSE
EDGPPPADIEEFDWPEEEYVAIASRDHPRIRGRLSLEAYLAERHAVVTPWSEPRGVVDLVLERMGLARSVALQLPSVLAA
PFVIGGSELIMTLPRRAAQRLAEAAGVRLYPAPFAIPPYRLKLYRHRRHAGSAAHDWVWRQLAACGPEARSP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=308, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33967; Mature: 33967

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIHPGLRGLDLNLLLLLDALFRAGSVQGAADSLAISASACSHALARLRLALGDQLFVR
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHHCCEEEEE
VGGGMRPTPRAEQLAPLVEAALALLSDGLARGAEFDPARSERRFVLAATDYTAFAVLPRF
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
LNRMQSLAPALSFRVLQAERKVPLDALLAGSIDFALGYSEEDGPPPADIEEFDWPEEEYV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCHHHEE
AIASRDHPRIRGRLSLEAYLAERHAVVTPWSEPRGVVDLVLERMGLARSVALQLPSVLAA
EEECCCCCCHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PFVIGGSELIMTLPRRAAQRLAEAAGVRLYPAPFAIPPYRLKLYRHRRHAGSAAHDWVWR
CHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
QLAACGPEARSP
HHHHCCCCCCCC
>Mature Secondary Structure
MKNIHPGLRGLDLNLLLLLDALFRAGSVQGAADSLAISASACSHALARLRLALGDQLFVR
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHHCCEEEEE
VGGGMRPTPRAEQLAPLVEAALALLSDGLARGAEFDPARSERRFVLAATDYTAFAVLPRF
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
LNRMQSLAPALSFRVLQAERKVPLDALLAGSIDFALGYSEEDGPPPADIEEFDWPEEEYV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCHHHEE
AIASRDHPRIRGRLSLEAYLAERHAVVTPWSEPRGVVDLVLERMGLARSVALQLPSVLAA
EEECCCCCCHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PFVIGGSELIMTLPRRAAQRLAEAAGVRLYPAPFAIPPYRLKLYRHRRHAGSAAHDWVWR
CHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
QLAACGPEARSP
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]