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The map label for this gene is nhaR [H]

Identifier: 34498565

GI number: 34498565

Start: 3397868

End: 3398749

Strand: Direct

Name: nhaR [H]

Synonym: CV_3110

Alternate gene names: 34498565

Gene position: 3397868-3398749 (Clockwise)

Preceding gene: 34498560

Following gene: 34498566

Centisome position: 71.52

GC content: 67.91

Gene sequence:

>882_bases
ATGGACAGGATCAATTACAAGCATCTGCACTATTTCTGGCATGTGGCGCGCGCCGGCAGCGTCACCCGCGCCGCCGGCCA
GTTGAACGTCAGCATGCAGACCATCAGCGGACAGATCACCAAGCTGGAACAGCAACTGGGACGTTCGCTGTTCCGCCAGC
AGGGCCGCGGCCTGGCATTGACCGAGGCCGGCCGGCTGGCGCTGGATTACGCCGACCGCATCTTCCTGCTGGGGGAAGAA
CTGGAGACGGCGCTGGCCGACCCGCTGCTGGACCAGACGCTGAGATTGGCCGCCGGCATTTCCGATGTCGTGCCCAAAGG
CATCGCCAGCCGGCTGCTGCGGCCGGCGCTGCGCACCAACGGCCGTTTGCGGCTCAGCTGCGGCGAAGGCGACTTCGATG
AGCTGATCGGCGAACTGGGCCGCCACCGGCTGGACCTGGTGCTGGCGGACCGCCCCGTGGCCAGCGGCGAGCAACAGCAG
TTCCAATCCTGGCCGCTGCTGCGCTGCCCGGTGCAGCTGCTGGCCGCGCCGGAGTTGCACGCCCGCTGCCAGGCCGGATT
CCCGGCCAGCCTGGAACAGGCGCCGCTGCTGCTGCCCAGCCGGGACAACGTGCTGCGCCGGCAACTGGAGCACTGGTTCG
ACGCGAACGGCGTCCGGCCCGACCTTGTCGGCGAATTCGATGATCATGCGTTGATGGAAACATTCGCCCGCCAGGGACTG
GGATTGTTGCCGGCGCCGGTTTCGCCCGACGGCGAAGCCGACCATCCCGGCCTGTTGCCGCTGGGCGCGCTGGACGGCGT
GTGGGAGCACTATTACGTCACCGCCAGCCGCCGCAAGCTGCAGCACCCCGCGCTGCAGGCGATTTTGCAAGCCTGGACAT
GA

Upstream 100 bases:

>100_bases
GGCCCGGTCTTGCGCCGGAGCCATGCTGCAGTGTATGACAGATAAAGCATCGAAAAAATAAAGTATTATCTGAATAATTC
TTCGAAATTTTCGAATAGAC

Downstream 100 bases:

>100_bases
GCCGCTGTGCCATGCAGGCGACAGACGGACCCGGCGGGCGGACCAGCGGCGGCGGCGGCGATTCCGCCGCGGGGAGTCTT
GGCTGATAATGGATTGAAGC

Product: transcriptional activator protein NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDRINYKHLHYFWHVARAGSVTRAAGQLNVSMQTISGQITKLEQQLGRSLFRQQGRGLALTEAGRLALDYADRIFLLGEE
LETALADPLLDQTLRLAAGISDVVPKGIASRLLRPALRTNGRLRLSCGEGDFDELIGELGRHRLDLVLADRPVASGEQQQ
FQSWPLLRCPVQLLAAPELHARCQAGFPASLEQAPLLLPSRDNVLRRQLEHWFDANGVRPDLVGEFDDHALMETFARQGL
GLLPAPVSPDGEADHPGLLPLGALDGVWEHYYVTASRRKLQHPALQAILQAWT

Sequences:

>Translated_293_residues
MDRINYKHLHYFWHVARAGSVTRAAGQLNVSMQTISGQITKLEQQLGRSLFRQQGRGLALTEAGRLALDYADRIFLLGEE
LETALADPLLDQTLRLAAGISDVVPKGIASRLLRPALRTNGRLRLSCGEGDFDELIGELGRHRLDLVLADRPVASGEQQQ
FQSWPLLRCPVQLLAAPELHARCQAGFPASLEQAPLLLPSRDNVLRRQLEHWFDANGVRPDLVGEFDDHALMETFARQGL
GLLPAPVSPDGEADHPGLLPLGALDGVWEHYYVTASRRKLQHPALQAILQAWT
>Mature_293_residues
MDRINYKHLHYFWHVARAGSVTRAAGQLNVSMQTISGQITKLEQQLGRSLFRQQGRGLALTEAGRLALDYADRIFLLGEE
LETALADPLLDQTLRLAAGISDVVPKGIASRLLRPALRTNGRLRLSCGEGDFDELIGELGRHRLDLVLADRPVASGEQQQ
FQSWPLLRCPVQLLAAPELHARCQAGFPASLEQAPLLLPSRDNVLRRQLEHWFDANGVRPDLVGEFDDHALMETFARQGL
GLLPAPVSPDGEADHPGLLPLGALDGVWEHYYVTASRRKLQHPALQAILQAWT

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=35.472972972973, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI157672245, Length=259, Percent_Identity=30.8880308880309, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32455; Mature: 32455

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRINYKHLHYFWHVARAGSVTRAAGQLNVSMQTISGQITKLEQQLGRSLFRQQGRGLAL
CCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TEAGRLALDYADRIFLLGEELETALADPLLDQTLRLAAGISDVVPKGIASRLLRPALRTN
ECCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
GRLRLSCGEGDFDELIGELGRHRLDLVLADRPVASGEQQQFQSWPLLRCPVQLLAAPELH
CEEEEEECCCCHHHHHHHHCHHHEEEEEECCCCCCCCHHHHHCCCHHHCCHHHHCCCCHH
ARCQAGFPASLEQAPLLLPSRDNVLRRQLEHWFDANGVRPDLVGEFDDHALMETFARQGL
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
GLLPAPVSPDGEADHPGLLPLGALDGVWEHYYVTASRRKLQHPALQAILQAWT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MDRINYKHLHYFWHVARAGSVTRAAGQLNVSMQTISGQITKLEQQLGRSLFRQQGRGLAL
CCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TEAGRLALDYADRIFLLGEELETALADPLLDQTLRLAAGISDVVPKGIASRLLRPALRTN
ECCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
GRLRLSCGEGDFDELIGELGRHRLDLVLADRPVASGEQQQFQSWPLLRCPVQLLAAPELH
CEEEEEECCCCHHHHHHHHCHHHEEEEEECCCCCCCCHHHHHCCCHHHCCHHHHCCCCHH
ARCQAGFPASLEQAPLLLPSRDNVLRRQLEHWFDANGVRPDLVGEFDDHALMETFARQGL
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
GLLPAPVSPDGEADHPGLLPLGALDGVWEHYYVTASRRKLQHPALQAILQAWT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]