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The map label for this gene is htpX1 [H]

Identifier: 34498564

GI number: 34498564

Start: 3396860

End: 3397741

Strand: Reverse

Name: htpX1 [H]

Synonym: CV_3109

Alternate gene names: 34498564

Gene position: 3397741-3396860 (Counterclockwise)

Preceding gene: 34498572

Following gene: 34498563

Centisome position: 71.52

GC content: 66.55

Gene sequence:

>882_bases
ATGAAACGGGTGATTTTGCTGATTGTGACCAACATCGCGGTGATGCTGGTTCTGAGCCTGAGCGTGCGATTGCTGGGCCT
GGATCGCTTCGTCACCGCCGGCGGCCTGAACCTGGGCATGCTGCTGATGTTCTCGGCGGTGCTGGGTTTCGGCGGCGCTT
TCATTTCCCTGGCCCTGTCCAAGACCATGGCCAAATGGAGCACCGGCGCGCGGGTGATCACGCAGCCGTCCGGCCAGACC
GAAGCCTGGCTGCTGAACACTGTGCGCAAGCTGGCCGACCGCGCCGGCCTGCCGATGCCGGAGGTGGCGGTGTACGAGGG
CGAGCCCAATGCTTTCGCCACCGGCCCCAGCCGCGCCAACTCGCTGGTGGCGGTGTCCACCGGCTTGCTGGCCAATATGA
ATGAGGAGGAAGTGGAGGCGGTGCTGGCGCACGAGATCGCCCACATCCGCAACGGCGATATGGTGACGCTGACGCTGATC
CAGGGCGTGGTCAACACCTTCGTCTATTTCCTGGCCCGGGTGGTCGGCTACCTGGTGGACAGCTGGCTGAAGCGCGACGA
GGAGAACGGTTCCGCCGGCACCGGGATCGGTTATTTCATCACGGTCATCGTCTGCGAGATCGTATTCGGCATCCTGGCTT
CCGTGGTGGTGATGTACTTCTCCCGCCAGCGCGAGTTCCGCGCCGACGCCGGCGCCGCCGAGCTGCTGGGCTCGCCCGTG
CCGATGGCCAACGCGCTGCGTCGTCTGGGCGGCATCGAGGCCGACGGCTTGCCCAAGAGCATGGCGGCTTCCGGGATCGC
CGGCGGCCGCGGCCTGCTGGGCCTGTTCGCCACCCACCCGAGCATGGAGGAGCGCATCGCCGCGCTGGAAGGCCGCGGTT
GA

Upstream 100 bases:

>100_bases
TTCAGATAATACTTTATTTTTTCGATGCTTTATCTGTCATACACTGCAGCATGGCTCCGGCGCAAGACCGGGCCGCGTTC
CACTTTTTGGAGAATGAAAC

Downstream 100 bases:

>100_bases
CGGAGCGGGCGGCGTATCCCGCCGCCCCACATTGATGAATTGAATGGAGTGTTGAAGTGATCGATTTTCTGACCGCCCCC
GCGCTGGGCTATCCGCTGTG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKRVILLIVTNIAVMLVLSLSVRLLGLDRFVTAGGLNLGMLLMFSAVLGFGGAFISLALSKTMAKWSTGARVITQPSGQT
EAWLLNTVRKLADRAGLPMPEVAVYEGEPNAFATGPSRANSLVAVSTGLLANMNEEEVEAVLAHEIAHIRNGDMVTLTLI
QGVVNTFVYFLARVVGYLVDSWLKRDEENGSAGTGIGYFITVIVCEIVFGILASVVVMYFSRQREFRADAGAAELLGSPV
PMANALRRLGGIEADGLPKSMAASGIAGGRGLLGLFATHPSMEERIAALEGRG

Sequences:

>Translated_293_residues
MKRVILLIVTNIAVMLVLSLSVRLLGLDRFVTAGGLNLGMLLMFSAVLGFGGAFISLALSKTMAKWSTGARVITQPSGQT
EAWLLNTVRKLADRAGLPMPEVAVYEGEPNAFATGPSRANSLVAVSTGLLANMNEEEVEAVLAHEIAHIRNGDMVTLTLI
QGVVNTFVYFLARVVGYLVDSWLKRDEENGSAGTGIGYFITVIVCEIVFGILASVVVMYFSRQREFRADAGAAELLGSPV
PMANALRRLGGIEADGLPKSMAASGIAGGRGLLGLFATHPSMEERIAALEGRG
>Mature_293_residues
MKRVILLIVTNIAVMLVLSLSVRLLGLDRFVTAGGLNLGMLLMFSAVLGFGGAFISLALSKTMAKWSTGARVITQPSGQT
EAWLLNTVRKLADRAGLPMPEVAVYEGEPNAFATGPSRANSLVAVSTGLLANMNEEEVEAVLAHEIAHIRNGDMVTLTLI
QGVVNTFVYFLARVVGYLVDSWLKRDEENGSAGTGIGYFITVIVCEIVFGILASVVVMYFSRQREFRADAGAAELLGSPV
PMANALRRLGGIEADGLPKSMAASGIAGGRGLLGLFATHPSMEERIAALEGRG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=293, Percent_Identity=49.1467576791809, Blast_Score=250, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31040; Mature: 31040

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVILLIVTNIAVMLVLSLSVRLLGLDRFVTAGGLNLGMLLMFSAVLGFGGAFISLALS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHH
KTMAKWSTGARVITQPSGQTEAWLLNTVRKLADRAGLPMPEVAVYEGEPNAFATGPSRAN
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCC
SLVAVSTGLLANMNEEEVEAVLAHEIAHIRNGDMVTLTLIQGVVNTFVYFLARVVGYLVD
CEEEEHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
SWLKRDEENGSAGTGIGYFITVIVCEIVFGILASVVVMYFSRQREFRADAGAAELLGSPV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
PMANALRRLGGIEADGLPKSMAASGIAGGRGLLGLFATHPSMEERIAALEGRG
CHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKRVILLIVTNIAVMLVLSLSVRLLGLDRFVTAGGLNLGMLLMFSAVLGFGGAFISLALS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHH
KTMAKWSTGARVITQPSGQTEAWLLNTVRKLADRAGLPMPEVAVYEGEPNAFATGPSRAN
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCC
SLVAVSTGLLANMNEEEVEAVLAHEIAHIRNGDMVTLTLIQGVVNTFVYFLARVVGYLVD
CEEEEHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
SWLKRDEENGSAGTGIGYFITVIVCEIVFGILASVVVMYFSRQREFRADAGAAELLGSPV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
PMANALRRLGGIEADGLPKSMAASGIAGGRGLLGLFATHPSMEERIAALEGRG
CHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA