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The map label for this gene is zur [H]

Identifier: 34498523

GI number: 34498523

Start: 3346882

End: 3347235

Strand: Reverse

Name: zur [H]

Synonym: CV_3068

Alternate gene names: 34498523

Gene position: 3347235-3346882 (Counterclockwise)

Preceding gene: 34498526

Following gene: 34498522

Centisome position: 70.45

GC content: 66.95

Gene sequence:

>354_bases
GTGCTGAAGCTGGTGCTGGGCCGCCGCGGCGTGGTCAAGGCCTACCAGGTGCTGGCCGATCTGCAGCAGCAGCGCGGCAA
CGCCGCGCCGCCGACCGTCTACCGCGCGCTGGACTTCCTGGTGGAGCACGGCCTGTTGCACAAGGTGGACGCGCTCAACG
GCTTCATCGTCTGCGATCATTTCGATTGCCAGCATGAGAGCCTGATCCTGGTGTGCGAGCAATGCGGCCGCGTCAATGAA
GTGGACGCCGCCGGAGGGCTGGCCAGCCTGCGTGAAATGGCGCAAGCCGCCGGCTTCGCGCTCAGTCCGCAAAACCTGGT
GCTGGCCGGACGCTGCCAGTCCTGTGCCGTCTGA

Upstream 100 bases:

>100_bases
CGAACCATGGCAAACCGAAATGGATTCCACCTCCTATCTCGCCGCCGCCGAGCGCCACTGCGCCGCGCGCGGCAGCAAGC
TGACCGAACTGCGCCGCCAG

Downstream 100 bases:

>100_bases
ATCTGAAGAAATCATGAACAACAAGACCAAAGTCAACCTGTTTACCGGCTTTCTGGGCGTCGGCAAGACCACCGCGCTGC
GCCACCTGATCGCCAACCGG

Product: transcriptional repressor of znuABC operon

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MLKLVLGRRGVVKAYQVLADLQQQRGNAAPPTVYRALDFLVEHGLLHKVDALNGFIVCDHFDCQHESLILVCEQCGRVNE
VDAAGGLASLREMAQAAGFALSPQNLVLAGRCQSCAV

Sequences:

>Translated_117_residues
MLKLVLGRRGVVKAYQVLADLQQQRGNAAPPTVYRALDFLVEHGLLHKVDALNGFIVCDHFDCQHESLILVCEQCGRVNE
VDAAGGLASLREMAQAAGFALSPQNLVLAGRCQSCAV
>Mature_117_residues
MLKLVLGRRGVVKAYQVLADLQQQRGNAAPPTVYRALDFLVEHGLLHKVDALNGFIVCDHFDCQHESLILVCEQCGRVNE
VDAAGGLASLREMAQAAGFALSPQNLVLAGRCQSCAV

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=116, Percent_Identity=38.7931034482759, Blast_Score=86, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 12603; Mature: 12603

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLVLGRRGVVKAYQVLADLQQQRGNAAPPTVYRALDFLVEHGLLHKVDALNGFIVCDH
CEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCEEEECC
FDCQHESLILVCEQCGRVNEVDAAGGLASLREMAQAAGFALSPQNLVLAGRCQSCAV
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLKLVLGRRGVVKAYQVLADLQQQRGNAAPPTVYRALDFLVEHGLLHKVDALNGFIVCDH
CEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCEEEECC
FDCQHESLILVCEQCGRVNEVDAAGGLASLREMAQAAGFALSPQNLVLAGRCQSCAV
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]