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The map label for this gene is mgtC [H]

Identifier: 34498476

GI number: 34498476

Start: 3298283

End: 3299032

Strand: Direct

Name: mgtC [H]

Synonym: CV_3021

Alternate gene names: 34498476

Gene position: 3298283-3299032 (Clockwise)

Preceding gene: 34498469

Following gene: 34498490

Centisome position: 69.42

GC content: 66.93

Gene sequence:

>750_bases
ATGGATCAGAGCTGGCAGCAATTGGCGGCCCTTTACTGGAGCGCGGGCAAATGGCAGATCAACCTGCTGGTGATCGCCCA
CCTGGCCGGCGGGCTGCTGCTGGGCAGCCTGCTCGGCTACGAGCGCTGGTACAACGGCCGCGCGGCCGGCATGCGCACCT
ACGGCCTGGTGTGCATGGCCTCGTCGGCGGCGATCAGCATCATCGGCTATTCCGGCTACTGGTACGGCGGCCAATCGGCC
GACATCATGCACGGCGACATGACCCGCGTGGCCCAAGGCGTGCTGACCGGCATCGGTTTCCTGGGCGCCGGCATGATCAT
GAAGGAAGGCTTGAGCATCAGCGGCCTGACGTCGGCCGCCTCGGTGTGGATGTCGTCGGTGATCGGCATCCTGATCGGCG
TCGGCTTCTACGCCGCGGCCATCGCGCTGACCGTGCTGTGCATGGTCTTCGTCACCGTGGTGAACCGCATCGAGAACATC
CTGCCGCGGCGGGTCAGCCTGTTCGTCAGCGTCAAGCTGAGCCCGGAACACGACTGGACGGTGGAGCGGTTGGCGGAACG
GCTGGCGCCGTCCGGGCTGAAGCTGCACGAGGAAAGCATCAGCGTGCGCGCCGACCCGTCCGGCGCCAGCTGGAGCTTCC
TGGTGTCCGCCCAGGACCGCCGCAGCTACATCAGCGTGGTGGACCTGGCCCGCGACATCATGATCGCCGACCACATCCTG
GAGCTGGACCTGCAGCCGGCGCGCAACTGA

Upstream 100 bases:

>100_bases
TAAGAGCGACAGCGCGCTTGGGAAAACGCCGGCCGTTATGCCATGATGCCGGCTTGAACGAACAGACATCGAACGCGCCC
GATGGCGGCGGAGGAAGGCA

Downstream 100 bases:

>100_bases
GCGCGCGCGGGCCCCTTACAGCGCCACGCCCGGCGGCGGCTGGTCGTGGCTTTGCGTCATCGACTGGTGCGGCAGCTCCA
GATAACTCTTGGACTGCATC

Product: Mg(2+) transport ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MDQSWQQLAALYWSAGKWQINLLVIAHLAGGLLLGSLLGYERWYNGRAAGMRTYGLVCMASSAAISIIGYSGYWYGGQSA
DIMHGDMTRVAQGVLTGIGFLGAGMIMKEGLSISGLTSAASVWMSSVIGILIGVGFYAAAIALTVLCMVFVTVVNRIENI
LPRRVSLFVSVKLSPEHDWTVERLAERLAPSGLKLHEESISVRADPSGASWSFLVSAQDRRSYISVVDLARDIMIADHIL
ELDLQPARN

Sequences:

>Translated_249_residues
MDQSWQQLAALYWSAGKWQINLLVIAHLAGGLLLGSLLGYERWYNGRAAGMRTYGLVCMASSAAISIIGYSGYWYGGQSA
DIMHGDMTRVAQGVLTGIGFLGAGMIMKEGLSISGLTSAASVWMSSVIGILIGVGFYAAAIALTVLCMVFVTVVNRIENI
LPRRVSLFVSVKLSPEHDWTVERLAERLAPSGLKLHEESISVRADPSGASWSFLVSAQDRRSYISVVDLARDIMIADHIL
ELDLQPARN
>Mature_249_residues
MDQSWQQLAALYWSAGKWQINLLVIAHLAGGLLLGSLLGYERWYNGRAAGMRTYGLVCMASSAAISIIGYSGYWYGGQSA
DIMHGDMTRVAQGVLTGIGFLGAGMIMKEGLSISGLTSAASVWMSSVIGILIGVGFYAAAIALTVLCMVFVTVVNRIENI
LPRRVSLFVSVKLSPEHDWTVERLAERLAPSGLKLHEESISVRADPSGASWSFLVSAQDRRSYISVVDLARDIMIADHIL
ELDLQPARN

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=120, Percent_Identity=35, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 26968; Mature: 26968

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSWQQLAALYWSAGKWQINLLVIAHLAGGLLLGSLLGYERWYNGRAAGMRTYGLVCMA
CCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEE
SSAAISIIGYSGYWYGGQSADIMHGDMTRVAQGVLTGIGFLGAGMIMKEGLSISGLTSAA
CCCEEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SVWMSSVIGILIGVGFYAAAIALTVLCMVFVTVVNRIENILPRRVSLFVSVKLSPEHDWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCH
VERLAERLAPSGLKLHEESISVRADPSGASWSFLVSAQDRRSYISVVDLARDIMIADHIL
HHHHHHHHCCCCCEEECCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ELDLQPARN
HCCCCCCCC
>Mature Secondary Structure
MDQSWQQLAALYWSAGKWQINLLVIAHLAGGLLLGSLLGYERWYNGRAAGMRTYGLVCMA
CCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEE
SSAAISIIGYSGYWYGGQSADIMHGDMTRVAQGVLTGIGFLGAGMIMKEGLSISGLTSAA
CCCEEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SVWMSSVIGILIGVGFYAAAIALTVLCMVFVTVVNRIENILPRRVSLFVSVKLSPEHDWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCH
VERLAERLAPSGLKLHEESISVRADPSGASWSFLVSAQDRRSYISVVDLARDIMIADHIL
HHHHHHHHCCCCCEEECCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ELDLQPARN
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA