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The map label for this gene is rbsK [H]

Identifier: 34498475

GI number: 34498475

Start: 3297107

End: 3297997

Strand: Reverse

Name: rbsK [H]

Synonym: CV_3020

Alternate gene names: 34498475

Gene position: 3297997-3297107 (Counterclockwise)

Preceding gene: 34498477

Following gene: 34498474

Centisome position: 69.42

GC content: 72.17

Gene sequence:

>891_bases
ATGACTCGGGTGCTGGTAGTCGGCAGTATCAATATGGACCTGGTGGTCACCGCCAGGCGGATGCCGAAACTGGGCGAAAC
GCTGCTGGGCGACGGTTTCGCCACCCATCCGGGCGGCAAGGGCGCCAATCAGGCGGTGGCCGCCGCCCGGCTCGGCGCCG
AGGTGGCGCTGCTGGGCTGCGTCGGCGACGACGCCTTCGGCCGCGATCTGCGCGCCCATCTGGAGCGGGAGGGCGTGGAT
TGCCGCGGCGTGGCGACCGTGCCCGGCCCCACCGGCATCGCCGCCATTACCGTCAGCGGCGGCGACAACGCCATCCTGGT
GGTGCCGGGCGCCAACCACCAGCTGACGCCGGCGCATCTGGACGCCGCCGAGCAGGCCTTCATCGACGCCGACGTGGTGC
TGACCCAGCTGGAAATTCCGCTGGCCGCGGTGCGCCGCGCCGCCGAACTGGCCGCCCGCCACAAGAAGCCGCTGCTGCTG
AATCCGGCGCCGGCGGTGCCGCTGCCGGAAGAGCTGCTGCAGCGCGTGACGCTGCTAACCCCCAACGAACACGAATTCCT
GACCATGCTGGCCCAGCCCGACGCCGACTGGCGCGCGCTCTTGGCCGAGCGCCCGGGCAAGTTGGTGATGACCCACGGCA
AGCACGGCGCCTATTTCGCGCTGGCGCGCGGCCAGTTGCGCCACCAGCCCGGCTTCGAGGTCCAGGCGGTGGACAGCACC
GGCGCCGGCGACACCTTCAACGGCGCGCTGGCGGCCTTCCTGCCGCTGGGCCTGGAAGAGGCGGTGCGCCGCGCCAACGC
GGCCGGCGCGCTGTCGGTCACCCGGCCGGGCGCGCAGGGCGGCATGCCGACGCTGGCCGAGCTGGAAGCCTTCCTGGAGA
ACAAAGCATGA

Upstream 100 bases:

>100_bases
GGCGCAGGCCAACTCTGCTATAAATCGGTGCTGATCACGTTTTAGCAAGAAAAACGCTATTTGTGCGCTGCAATGTAGCA
AAGGTACACAAGGAGACGGC

Downstream 100 bases:

>100_bases
AGAAGCACGGCCATCTGAACCGCGACATCGCCCGCATTCTGGCGTCCATGGGCCATACCGACAGCCTGGTGATCGCCGAC
TGCGGCCTGCCCATCCCGCC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTRVLVVGSINMDLVVTARRMPKLGETLLGDGFATHPGGKGANQAVAAARLGAEVALLGCVGDDAFGRDLRAHLEREGVD
CRGVATVPGPTGIAAITVSGGDNAILVVPGANHQLTPAHLDAAEQAFIDADVVLTQLEIPLAAVRRAAELAARHKKPLLL
NPAPAVPLPEELLQRVTLLTPNEHEFLTMLAQPDADWRALLAERPGKLVMTHGKHGAYFALARGQLRHQPGFEVQAVDST
GAGDTFNGALAAFLPLGLEEAVRRANAAGALSVTRPGAQGGMPTLAELEAFLENKA

Sequences:

>Translated_296_residues
MTRVLVVGSINMDLVVTARRMPKLGETLLGDGFATHPGGKGANQAVAAARLGAEVALLGCVGDDAFGRDLRAHLEREGVD
CRGVATVPGPTGIAAITVSGGDNAILVVPGANHQLTPAHLDAAEQAFIDADVVLTQLEIPLAAVRRAAELAARHKKPLLL
NPAPAVPLPEELLQRVTLLTPNEHEFLTMLAQPDADWRALLAERPGKLVMTHGKHGAYFALARGQLRHQPGFEVQAVDST
GAGDTFNGALAAFLPLGLEEAVRRANAAGALSVTRPGAQGGMPTLAELEAFLENKA
>Mature_295_residues
TRVLVVGSINMDLVVTARRMPKLGETLLGDGFATHPGGKGANQAVAAARLGAEVALLGCVGDDAFGRDLRAHLEREGVDC
RGVATVPGPTGIAAITVSGGDNAILVVPGANHQLTPAHLDAAEQAFIDADVVLTQLEIPLAAVRRAAELAARHKKPLLLN
PAPAVPLPEELLQRVTLLTPNEHEFLTMLAQPDADWRALLAERPGKLVMTHGKHGAYFALARGQLRHQPGFEVQAVDSTG
AGDTFNGALAAFLPLGLEEAVRRANAAGALSVTRPGAQGGMPTLAELEAFLENKA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=37.1621621621622, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=41.9141914191419, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=32.013201320132, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789432, Length=315, Percent_Identity=29.8412698412698, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788491, Length=306, Percent_Identity=24.5098039215686, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=38.3333333333333, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=31.8181818181818, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=39.0728476821192, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=32.7868852459016, Blast_Score=121, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30848; Mature: 30717

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLVVGSINMDLVVTARRMPKLGETLLGDGFATHPGGKGANQAVAAARLGAEVALLGC
CCEEEEEECCCCEEEEEEHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEE
VGDDAFGRDLRAHLEREGVDCRGVATVPGPTGIAAITVSGGDNAILVVPGANHQLTPAHL
ECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHH
DAAEQAFIDADVVLTQLEIPLAAVRRAAELAARHKKPLLLNPAPAVPLPEELLQRVTLLT
CHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHEECC
PNEHEFLTMLAQPDADWRALLAERPGKLVMTHGKHGAYFALARGQLRHQPGFEVQAVDST
CCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCC
GAGDTFNGALAAFLPLGLEEAVRRANAAGALSVTRPGAQGGMPTLAELEAFLENKA
CCCCCCCCHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TRVLVVGSINMDLVVTARRMPKLGETLLGDGFATHPGGKGANQAVAAARLGAEVALLGC
CEEEEEECCCCEEEEEEHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEE
VGDDAFGRDLRAHLEREGVDCRGVATVPGPTGIAAITVSGGDNAILVVPGANHQLTPAHL
ECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHH
DAAEQAFIDADVVLTQLEIPLAAVRRAAELAARHKKPLLLNPAPAVPLPEELLQRVTLLT
CHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHEECC
PNEHEFLTMLAQPDADWRALLAERPGKLVMTHGKHGAYFALARGQLRHQPGFEVQAVDST
CCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCC
GAGDTFNGALAAFLPLGLEEAVRRANAAGALSVTRPGAQGGMPTLAELEAFLENKA
CCCCCCCCHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]